Protein Description

Gene Symbol PITPNB
Entrez ID 23760
Uniprot ID P48739
Description phosphatidylinositol transfer protein beta
Chromosomal Location chr22: 27,851,669-27,920,134
Ontology GO ID GO Term Definition Evidence

BP

GO:0006629

lipid metabolic process

The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.

NAS

BP

GO:0006890

retrograde vesicle-mediated transport, Golgi to ER

The directed movement of substances from the Golgi back to the endoplasmic reticulum, mediated by vesicles bearing specific protein coats such as COPI or COG.

TAS

BP

GO:0006997

nucleus organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus.

TAS

BP

GO:0015914

phospholipid transport

The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester.

TAS

CC

GO:0000139

Golgi membrane

The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

TAS

CC

GO:0005789

endoplasmic reticulum membrane

The lipid bilayer surrounding the endoplasmic reticulum.

TAS

CC

GO:0070062

extracellular exosome

A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.

IDA

MF

GO:0008289

lipid binding

Interacting selectively and non-covalently with a lipid.

IEA

Domain ID Description

IPR001666

Phosphatidylinositol transfer protein

IPR023393

START-like domain

No pathways found.

No diseases found.

Tissue Cell Type

epididymis

glandular cells

oral mucosa

squamous epithelial cells

skin

epidermal cells

tonsil

squamous epithelial cells

urinary bladder

urothelial cells

vagina

squamous epithelial cells

No databases found.

Pubmed ID Author Year Title

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

LMO4

8543

P61968

0.63

ACO2

50

Q99798

0.49

ADK

132

P55263

0.49

ESD

2098

P10768

0.49

ETFB

2109

P38117

0.49

GOT1

2805

P17174

0.49

HSPB1

3315

P04792

0.49

ALDH6A1

4329

Q02252

0.49

MPI

4351

P34949

0.49

OAT

4942

P04181

0.49

PCBP1

5093

Q15365

0.49

SOD1

6647

P00441

0.49

TALDO1

6888

P37837

0.49

TIA1

7072

P31483

0.49

TKT

7086

P29401

0.49

GLRX2

51022

Q9NS18

0.49

PGM2L1

283209

Q6PCE3

0.49

ELAVL1

1994

Q15717

0.63

ENO1

2023

P06733

0.63

MOV10

4343

Q9HCE1

0.63

NTRK1

4914

P04629

0.63

VHL

7428

P40337

0.63

USP7

7874

Q93009

0.63

IKBKE

9641

Q14164

0.63

NXF1

10482

Q9UBU9

0.63

DNAJC11

55735

Q9NVH1

0.72