| Gene Symbol | PITPNB |
| Entrez ID | 23760 |
| Uniprot ID | P48739 |
| Description | phosphatidylinositol transfer protein beta |
| Chromosomal Location | chr22: 27,851,669-27,920,134 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
BP | GO:0006629 | lipid metabolic process |
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids. | NAS |
BP | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER |
The directed movement of substances from the Golgi back to the endoplasmic reticulum, mediated by vesicles bearing specific protein coats such as COPI or COG. | TAS |
BP | GO:0006997 | nucleus organization |
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus. | TAS |
BP | GO:0015914 | phospholipid transport |
The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester. | TAS |
CC | GO:0000139 | Golgi membrane |
The lipid bilayer surrounding any of the compartments of the Golgi apparatus. | TAS |
CC | GO:0005789 | endoplasmic reticulum membrane |
The lipid bilayer surrounding the endoplasmic reticulum. | TAS |
CC | GO:0070062 | extracellular exosome |
A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. | IDA |
MF | GO:0008289 | lipid binding |
Interacting selectively and non-covalently with a lipid. | IEA |
| Domain ID | Description |
|---|---|
IPR001666 | Phosphatidylinositol transfer protein |
IPR023393 | START-like domain |
| Tissue | Cell Type |
|---|---|
epididymis | glandular cells |
oral mucosa | squamous epithelial cells |
skin | epidermal cells |
tonsil | squamous epithelial cells |
urinary bladder | urothelial cells |
vagina | squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
22951915 | Haozi et al. | 2012 | Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
LMO4 | 8543 | P61968 | 0.63 |
ACO2 | 50 | Q99798 | 0.49 |
ADK | 132 | P55263 | 0.49 |
ESD | 2098 | P10768 | 0.49 |
ETFB | 2109 | P38117 | 0.49 |
GOT1 | 2805 | P17174 | 0.49 |
HSPB1 | 3315 | P04792 | 0.49 |
ALDH6A1 | 4329 | Q02252 | 0.49 |
MPI | 4351 | P34949 | 0.49 |
OAT | 4942 | P04181 | 0.49 |
PCBP1 | 5093 | Q15365 | 0.49 |
SOD1 | 6647 | P00441 | 0.49 |
TALDO1 | 6888 | P37837 | 0.49 |
TIA1 | 7072 | P31483 | 0.49 |
TKT | 7086 | P29401 | 0.49 |
GLRX2 | 51022 | Q9NS18 | 0.49 |
PGM2L1 | 283209 | Q6PCE3 | 0.49 |
ELAVL1 | 1994 | Q15717 | 0.63 |
ENO1 | 2023 | P06733 | 0.63 |
MOV10 | 4343 | Q9HCE1 | 0.63 |
NTRK1 | 4914 | P04629 | 0.63 |
VHL | 7428 | P40337 | 0.63 |
USP7 | 7874 | Q93009 | 0.63 |
IKBKE | 9641 | Q14164 | 0.63 |
NXF1 | 10482 | Q9UBU9 | 0.63 |
DNAJC11 | 55735 | Q9NVH1 | 0.72 |