Gene Symbol | TSPAN12 |
Entrez ID | 23554 |
Uniprot ID | O95859 |
Description | tetraspanin 12 |
Chromosomal Location | chr7: 120,787,320-120,858,402 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0001525 |
angiogenesis |
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels. |
IEA |
BP |
GO:0007166 |
cell surface receptor signaling pathway |
A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription. |
IBA|ISS |
BP |
GO:0010842 |
retina layer formation |
The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia. |
ISS |
BP |
GO:0045765 |
regulation of angiogenesis |
Any process that modulates the frequency, rate or extent of angiogenesis. |
ISS |
CC |
GO:0005887 |
integral component of plasma membrane |
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IBA|ISS |
CC |
GO:0016020 |
membrane |
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
TAS |
CC |
GO:0016021 |
integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
TAS |
Domain ID | Description |
---|---|
IPR000301 |
Tetraspanin |
IPR008952 |
Tetraspanin, EC2 domain |
IPR018499 |
Tetraspanin/Peripherin |
IPR018503 |
Tetraspanin, conserved site |
Tissue | Cell Type |
---|---|
lung |
macrophages |
placenta |
decidual cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
FZD4 |
8322 |
Q9ULV1 |
0.52 |
NDP |
4693 |
Q00604 |
0.63 |
TFCP2 |
7024 |
Q12800 |
0.63 |