Gene Symbol | MORC3 |
Entrez ID | 23515 |
Uniprot ID | Q14149 |
Description | MORC family CW-type zinc finger 3 |
Chromosomal Location | chr21: 36,320,189-36,386,148 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006468 |
protein phosphorylation |
The process of introducing a phosphate group on to a protein. |
IDA |
BP |
GO:0007569 |
cell aging |
An aging process that has as participant a cell after a cell has stopped dividing. Cell aging may occur when a cell has temporarily stopped dividing through cell cycle arrest (GO:0007050) or when a cell has permanently stopped dividing, in which case it is undergoing cellular senescence (GO:0090398). May precede cell death (GO:0008219) and succeed cell maturation (GO:0048469). |
IDA |
BP |
GO:0009791 |
post-embryonic development |
The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development. |
IEA |
BP |
GO:0016032 |
viral process |
A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle. |
IEA |
BP |
GO:0018105 |
peptidyl-serine phosphorylation |
The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine. |
IDA |
BP |
GO:0048147 |
negative regulation of fibroblast proliferation |
Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells. |
IDA |
BP |
GO:0050821 |
protein stabilization |
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation. |
IDA |
BP |
GO:0051457 |
maintenance of protein location in nucleus |
Any process in which a protein is maintained in the nucleus and prevented from moving elsewhere. These include sequestration within the nucleus, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the nucleus. |
IDA|IMP |
CC |
GO:0005654 |
nucleoplasm |
That part of the nuclear content other than the chromosomes or the nucleolus. |
IDA |
CC |
GO:0016363 |
nuclear matrix |
The dense fibrillar network lying on the inner side of the nuclear membrane. |
IEA |
CC |
GO:0016605 |
PML body |
A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection. |
IDA |
MF |
GO:0003723 |
RNA binding |
Interacting selectively and non-covalently with an RNA molecule or a portion thereof. |
IEA |
MF |
GO:0008270 |
zinc ion binding |
Interacting selectively and non-covalently with zinc (Zn) ions. |
IEA |
Domain ID | Description |
---|---|
IPR003594 |
Histidine kinase-like ATPase, C-terminal domain |
IPR011124 |
Zinc finger, CW-type |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
WP2916 |
Interactome of polycomb repressive complex 2 (PRC2) |
WikiPathways |
UMLS CUI | UMLS Term |
---|---|
C0013080 |
Down Syndrome |
C0151786 |
Muscle Weakness |
Tissue | Cell Type |
---|---|
adrenal gland |
glandular cells |
bone marrow |
hematopoietic cells |
breast |
glandular cells |
bronchus |
respiratory epithelial cells |
caudate |
neuronal cells |
cerebellum |
cells in molecular layer |
cerebellum |
Purkinje cells |
cerebral cortex |
neuronal cells |
cerebral cortex |
neuropil |
colon |
endothelial cells |
colon |
peripheral nerve/ganglion |
duodenum |
glandular cells |
endometrium |
glandular cells |
gallbladder |
glandular cells |
heart muscle |
myocytes |
hippocampus |
neuronal cells |
kidney |
cells in tubules |
lung |
pneumocytes |
lymph node |
non-germinal center cells |
nasopharynx |
respiratory epithelial cells |
pancreas |
exocrine glandular cells |
parathyroid gland |
glandular cells |
placenta |
decidual cells |
placenta |
trophoblastic cells |
prostate |
glandular cells |
skin |
fibroblasts |
skin |
epidermal cells |
small intestine |
glandular cells |
soft tissue |
adipocytes |
soft tissue |
fibroblasts |
spleen |
cells in red pulp |
spleen |
cells in white pulp |
stomach |
glandular cells |
tonsil |
germinal center cells |
tonsil |
non-germinal center cells |
tonsil |
squamous epithelial cells |
urinary bladder |
urothelial cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
RDH10 |
157506 |
Q8IZV5 |
0.63 |
HTT |
3064 |
P42858 |
0.72 |
SNTB1 |
6641 |
Q13884 |
0.72 |
MOGS |
7841 |
Q13724 |
0.72 |
DYNLL1 |
8655 |
P63167 |
0.72 |
CRIPT |
9419 |
Q9P021 |
0.72 |
TRIB1 |
10221 |
Q96RU8 |
0.72 |
SYNE2 |
23224 |
Q8WXH0 |
0.72 |
DEPDC1 |
55635 |
Q5TB30 |
0.72 |
DOCK8 |
81704 |
Q8NF50 |
0.72 |
HIST1H2BC; HIST1H2BE; HIST1H2BF; HIST1H2BG; HIST1H2BI |
8339 |
P62807 |
0.49 |
HIST1H3A |
8350 |
P68431 |
0.49 |
KPNA2 |
3838 |
P52292 |
0.63 |
RAD23A |
5886 |
P54725 |
0.63 |
ROR1 |
4919 |
Q01973 |
0.72 |
SUMO2 |
6613 |
P61956 |
0.74 |