Protein Description

Gene Symbol MORC3
Entrez ID 23515
Uniprot ID Q14149
Description MORC family CW-type zinc finger 3
Chromosomal Location chr21: 36,320,189-36,386,148
Ontology GO ID GO Term Definition Evidence

BP

GO:0006468

protein phosphorylation

The process of introducing a phosphate group on to a protein.

IDA

BP

GO:0007569

cell aging

An aging process that has as participant a cell after a cell has stopped dividing. Cell aging may occur when a cell has temporarily stopped dividing through cell cycle arrest (GO:0007050) or when a cell has permanently stopped dividing, in which case it is undergoing cellular senescence (GO:0090398). May precede cell death (GO:0008219) and succeed cell maturation (GO:0048469).

IDA

BP

GO:0009791

post-embryonic development

The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development.

IEA

BP

GO:0016032

viral process

A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle.

IEA

BP

GO:0018105

peptidyl-serine phosphorylation

The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.

IDA

BP

GO:0048147

negative regulation of fibroblast proliferation

Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells.

IDA

BP

GO:0050821

protein stabilization

Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.

IDA

BP

GO:0051457

maintenance of protein location in nucleus

Any process in which a protein is maintained in the nucleus and prevented from moving elsewhere. These include sequestration within the nucleus, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the nucleus.

IDA|IMP

CC

GO:0005654

nucleoplasm

That part of the nuclear content other than the chromosomes or the nucleolus.

IDA

CC

GO:0016363

nuclear matrix

The dense fibrillar network lying on the inner side of the nuclear membrane.

IEA

CC

GO:0016605

PML body

A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection.

IDA

MF

GO:0003723

RNA binding

Interacting selectively and non-covalently with an RNA molecule or a portion thereof.

IEA

MF

GO:0008270

zinc ion binding

Interacting selectively and non-covalently with zinc (Zn) ions.

IEA

Domain ID Description

IPR003594

Histidine kinase-like ATPase, C-terminal domain

IPR011124

Zinc finger, CW-type

Pathway ID Pathway Term Pathway Source

WP2916

Interactome of polycomb repressive complex 2 (PRC2)

WikiPathways

UMLS CUI UMLS Term

C0013080

Down Syndrome

C0151786

Muscle Weakness

Tissue Cell Type

adrenal gland

glandular cells

bone marrow

hematopoietic cells

breast

glandular cells

bronchus

respiratory epithelial cells

caudate

neuronal cells

cerebellum

cells in molecular layer

cerebellum

Purkinje cells

cerebral cortex

neuronal cells

cerebral cortex

neuropil

colon

endothelial cells

colon

peripheral nerve/ganglion

duodenum

glandular cells

endometrium

glandular cells

gallbladder

glandular cells

heart muscle

myocytes

hippocampus

neuronal cells

kidney

cells in tubules

lung

pneumocytes

lymph node

non-germinal center cells

nasopharynx

respiratory epithelial cells

pancreas

exocrine glandular cells

parathyroid gland

glandular cells

placenta

decidual cells

placenta

trophoblastic cells

prostate

glandular cells

skin

fibroblasts

skin

epidermal cells

small intestine

glandular cells

soft tissue

adipocytes

soft tissue

fibroblasts

spleen

cells in red pulp

spleen

cells in white pulp

stomach

glandular cells

tonsil

germinal center cells

tonsil

non-germinal center cells

tonsil

squamous epithelial cells

urinary bladder

urothelial cells

No databases found.

Pubmed ID Author Year Title

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

RDH10

157506

Q8IZV5

0.63

HTT

3064

P42858

0.72

SNTB1

6641

Q13884

0.72

MOGS

7841

Q13724

0.72

DYNLL1

8655

P63167

0.72

CRIPT

9419

Q9P021

0.72

TRIB1

10221

Q96RU8

0.72

SYNE2

23224

Q8WXH0

0.72

DEPDC1

55635

Q5TB30

0.72

DOCK8

81704

Q8NF50

0.72

HIST1H2BC; HIST1H2BE; HIST1H2BF; HIST1H2BG; HIST1H2BI

8339

P62807

0.49

HIST1H3A

8350

P68431

0.49

KPNA2

3838

P52292

0.63

RAD23A

5886

P54725

0.63

ROR1

4919

Q01973

0.72

SUMO2

6613

P61956

0.74