| Gene Symbol | LRRC8B |
| Entrez ID | 23507 |
| Uniprot ID | Q6P9F7 |
| Description | leucine-rich repeat containing 8 family member B |
| Chromosomal Location | chr1: 89,524,836-89,597,864 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0098656 |
anion transmembrane transport |
A process in which an anion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. |
IMP |
|
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
IDA |
|
CC |
GO:0005789 |
endoplasmic reticulum membrane |
The lipid bilayer surrounding the endoplasmic reticulum. |
IEA |
|
CC |
GO:0005886 |
plasma membrane |
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
IDA |
|
CC |
GO:0016021 |
integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IEA |
|
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
| Domain ID | Description |
|---|---|
|
IPR001611 |
Leucine-rich repeat |
|
IPR003591 |
Leucine-rich repeat, typical subtype |
|
IPR021040 |
LRRC8, pannexin-like TM region |
|
IPR026906 |
Leucine rich repeat 5 |
|
IPR032675 |
Leucine-rich repeat domain, L domain-like |
| Tissue | Cell Type |
|---|---|
|
caudate |
neuronal cells |
|
cerebellum |
Purkinje cells |
|
cerebral cortex |
neuronal cells |
|
colon |
endothelial cells |
|
colon |
peripheral nerve/ganglion |
|
hippocampus |
neuronal cells |
|
placenta |
decidual cells |
|
skin |
fibroblasts |
|
skin |
epidermal cells |
|
soft tissue |
fibroblasts |
|
testis |
cells in seminiferous ducts |
|
tonsil |
squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
CUL3 |
8452 |
Q13618 |
0.63 |