| Gene Symbol | LRRC8B |
| Entrez ID | 23507 |
| Uniprot ID | Q6P9F7 |
| Description | leucine-rich repeat containing 8 family member B |
| Chromosomal Location | chr1: 89,524,836-89,597,864 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
BP | GO:0098656 | anion transmembrane transport |
A process in which an anion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. | IMP |
CC | GO:0005737 | cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. | IDA |
CC | GO:0005789 | endoplasmic reticulum membrane |
The lipid bilayer surrounding the endoplasmic reticulum. | IEA |
CC | GO:0005886 | plasma membrane |
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. | IDA |
CC | GO:0016021 | integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. | IEA |
MF | GO:0005515 | protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). | IPI |
| Domain ID | Description |
|---|---|
IPR001611 | Leucine-rich repeat |
IPR003591 | Leucine-rich repeat, typical subtype |
IPR021040 | LRRC8, pannexin-like TM region |
IPR026906 | Leucine rich repeat 5 |
IPR032675 | Leucine-rich repeat domain, L domain-like |
| Tissue | Cell Type |
|---|---|
caudate | neuronal cells |
cerebellum | Purkinje cells |
cerebral cortex | neuronal cells |
colon | endothelial cells |
colon | peripheral nerve/ganglion |
hippocampus | neuronal cells |
placenta | decidual cells |
skin | fibroblasts |
skin | epidermal cells |
soft tissue | fibroblasts |
testis | cells in seminiferous ducts |
tonsil | squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
22617121 | Ouandaogo et al. | 2012 | Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
CUL3 | 8452 | Q13618 | 0.63 |