Gene Symbol | SLC35A3 |
Entrez ID | 23443 |
Uniprot ID | Q9Y2D2 |
Description | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 |
Chromosomal Location | chr1: 99,969,351-100,035,637 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006047 |
UDP-N-acetylglucosamine metabolic process |
The chemical reactions and pathways involving UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate. |
TAS |
BP |
GO:0008643 |
carbohydrate transport |
The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are any of a group of organic compounds based of the general formula Cx(H2O)y. |
IEA |
BP |
GO:0015788 |
UDP-N-acetylglucosamine transport |
The directed movement of UDP-N-acetylglucosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. N-acetylglucosamine is a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate. |
IMP |
BP |
GO:0015992 |
proton transport |
The directed movement of protons (hydrogen ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
IEA |
BP |
GO:1990569 |
UDP-N-acetylglucosamine transmembrane transport |
The directed movement of UDP-N-acetylglucosamine across a membrane. |
IEA |
CC |
GO:0000139 |
Golgi membrane |
The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
TAS |
CC |
GO:0005794 |
Golgi apparatus |
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions. |
TAS |
CC |
GO:0016021 |
integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IEA |
MF |
GO:0005351 |
sugar:proton symporter activity |
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sugar(out) + H+(out) = sugar(in) + H+(in). |
IEA |
MF |
GO:0005462 |
UDP-N-acetylglucosamine transmembrane transporter activity |
Enables the transfer of a UDP-N-acetylglucosamine from one side of the membrane to the other. N-acetylglucosamine is a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate. |
TAS |
Domain ID | Description |
---|---|
IPR007271 |
Nucleotide-sugar transporter |
Tissue | Cell Type |
---|---|
placenta |
decidual cells |
rectum |
glandular cells |
skeletal muscle |
myocytes |
skin |
Langerhans |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
SLC35A3 |
23443 |
Q9Y2D2 |
0.65 |
TP63 |
8626 |
Q9H3D4 |
0.63 |
CRADD |
8738 |
P78560 |
0.63 |
SLC35A2 |
7355 |
P78381 |
0.73 |