Gene Symbol | CHKB |
Entrez ID | 1120 |
Uniprot ID | Q9Y259 |
Description | choline kinase beta |
Chromosomal Location | chr22: 50,578,949-50,601,455 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006646 |
phosphatidylethanolamine biosynthetic process |
The chemical reactions and pathways resulting in the formation of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine. |
IDA|IEA|TAS |
BP |
GO:0006656 |
phosphatidylcholine biosynthetic process |
The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. |
TAS |
BP |
GO:0006657 |
CDP-choline pathway |
The phosphatidylcholine biosynthetic process that begins with the phosphorylation of choline and ends with the combination of CDP-choline with diacylglycerol to form phosphatidylcholine. |
IEA |
BP |
GO:0016310 |
phosphorylation |
The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. |
IEA |
CC |
GO:0005829 |
cytosol |
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
TAS |
MF |
GO:0004103 |
choline kinase activity |
Catalysis of the reaction: ATP + choline = ADP + choline phosphate + 2 H(+). |
IDA|TAS |
MF |
GO:0004305 |
ethanolamine kinase activity |
Catalysis of the reaction: ATP + ethanolamine = ADP + 2 H(+) + phosphoethanolamine. |
IDA|TAS |
MF |
GO:0005524 |
ATP binding |
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
IEA |
Domain ID | Description |
---|---|
IPR011009 |
Protein kinase-like domain |
IPR026712 |
Choline/Ethanolamine kinase |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa00564 |
Glycerophospholipid metabolism |
KEGG |
hsa01100 |
Metabolic pathways |
KEGG |
hsa05231 |
Choline metabolism in cancer |
KEGG |
WP2533 |
Glycerophospholipid Biosynthetic Pathway |
WikiPathways |
WP143 |
Fatty Acid Beta Oxidation |
WikiPathways |
WP3933 |
Kennedy pathway |
WikiPathways |
WP3940 |
One carbon metabolism and related pathways |
WikiPathways |
UMLS CUI | UMLS Term |
---|---|
C0027404 |
Narcolepsy |
Tissue | Cell Type |
---|---|
pancreas |
exocrine glandular cells |
placenta |
decidual cells |
placenta |
trophoblastic cells |
smooth muscle |
smooth muscle cells |
thyroid gland |
glandular cells |
tonsil |
non-germinal center cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
ALB |
213 |
P02768 |
0.72 |