| Gene Symbol | LARP1 |
| Entrez ID | 23367 |
| Uniprot ID | Q6PKG0 |
| Description | La ribonucleoprotein domain family member 1 |
| Chromosomal Location | chr5: 154,712,902-154,817,607 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0006413 |
translational initiation |
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA. |
IMP |
|
BP |
GO:0008283 |
cell proliferation |
The multiplication or reproduction of cells, resulting in the expansion of a cell population. |
IMP |
|
BP |
GO:0016239 |
positive regulation of macroautophagy |
Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation. |
IMP |
|
BP |
GO:0031929 |
TOR signaling |
A series of molecular signals mediated by TOR (Target of rapamycin) proteins, members of the phosphoinositide (PI) 3-kinase related kinase (PIKK) family that act as serine/threonine kinases in response to nutrient availability or growth factors. |
IMP |
|
BP |
GO:0045070 |
positive regulation of viral genome replication |
Any process that activates or increases the frequency, rate or extent of viral genome replication. |
IMP |
|
BP |
GO:0045727 |
positive regulation of translation |
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA. |
IEA |
|
BP |
GO:0098609 |
cell-cell adhesion |
The attachment of one cell to another cell via adhesion molecules. |
IEA |
|
CC |
GO:0005654 |
nucleoplasm |
That part of the nuclear content other than the chromosomes or the nucleolus. |
IDA |
|
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
IDA |
|
CC |
GO:0005913 |
cell-cell adherens junction |
An adherens junction which connects a cell to another cell. |
IDA |
|
CC |
GO:0016020 |
membrane |
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
IDA |
|
CC |
GO:0031931 |
TORC1 complex |
A protein complex that contains at least TOR (target of rapamycin) and Raptor (regulatory-associated protein of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of S6K. In Saccharomyces, the complex contains Kog1p, Lst8p, Tco89p, and either Tor1p or Tor2p. |
IDA |
|
MF |
GO:0000339 |
RNA cap binding |
Interacting selectively and non-covalently with a 7-methylguanosine (m7G) group or derivative located at the 5' end of an RNA molecule. |
IDA |
|
MF |
GO:0003730 |
mRNA 3'-UTR binding |
Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule. |
IDA |
|
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
|
MF |
GO:0008190 |
eukaryotic initiation factor 4E binding |
Interacting selectively and non-covalently with eukaryotic initiation factor 4E, a polypeptide factor involved in the initiation of ribosome-mediated translation. |
IPI |
|
MF |
GO:0008494 |
translation activator activity |
Any of a group of soluble proteins functioning in the activation of ribosome-mediated translation of mRNA into a polypeptide. |
IMP |
|
MF |
GO:0031369 |
translation initiation factor binding |
Interacting selectively and non-covalently with a translation initiation factor, any polypeptide factor involved in the initiation of ribosome-mediated translation. |
IDA |
|
MF |
GO:0044822 |
poly(A) RNA binding |
Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases. |
IDA |
|
MF |
GO:0048027 |
mRNA 5'-UTR binding |
Interacting selectively and non-covalently with the 5' untranslated region of an mRNA molecule. |
IDA |
|
MF |
GO:0098641 |
cadherin binding involved in cell-cell adhesion |
Any cadherin binding that occurs as part of the process of cell-cell adhesion. |
IDA |
| Domain ID | Description |
|---|---|
|
IPR006607 |
Protein of unknown function DM15 |
|
IPR006630 |
RNA-binding protein Lupus La |
|
IPR011991 |
Winged helix-turn-helix DNA-binding domain |
| Tissue | Cell Type |
|---|---|
|
appendix |
glandular cells |
|
cerebellum |
Purkinje cells |
|
cerebral cortex |
neuronal cells |
|
colon |
glandular cells |
|
duodenum |
glandular cells |
|
endometrium |
glandular cells |
|
esophagus |
squamous epithelial cells |
|
fallopian tube |
glandular cells |
|
lymph node |
germinal center cells |
|
lymph node |
non-germinal center cells |
|
oral mucosa |
squamous epithelial cells |
|
pancreas |
exocrine glandular cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
skin |
epidermal cells |
|
stomach |
glandular cells |
|
tonsil |
germinal center cells |
|
tonsil |
squamous epithelial cells |
|
vagina |
squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
CALM2 |
805 |
P62158 |
0.63 |
|
CALM3 |
808 |
P62158 |
0.63 |
|
CLCN6 |
1185 |
P51797 |
0.63 |
|
CSH1|CSH2 |
1442 |
P0DML2|P0DML3 |
0.63 |
|
DDX3X |
1654 |
O00571 |
0.63 |
|
DDX6 |
1656 |
P26196 |
0.63 |
|
EEF1A1 |
1915 |
P68104 |
0.63 |
|
GAPDH |
2597 |
P04406 |
0.63 |
|
GOLGA4 |
2803 |
Q13439 |
0.63 |
|
GOLGB1 |
2804 |
Q14789 |
0.63 |
|
GPI |
2821 |
P06744 |
0.63 |
|
HSPA8 |
3312 |
P11142 |
0.63 |
|
IK |
3550 |
Q13123 |
0.63 |
|
ILF3 |
3609 |
Q12906 |
0.63 |
|
KIF5A |
3798 |
Q12840 |
0.63 |
|
KIF5C |
3800 |
O60282 |
0.63 |
|
KPNA4 |
3839 |
O00629 |
0.63 |
|
RPSA |
3921 |
P08865 |
0.63 |
|
MT1JP |
4498 |
N/A |
0.63 |
|
NACA |
4666 |
Q13765 |
0.63 |
|
NAP1L1 |
4673 |
P55209 |
0.63 |
|
NEFM |
4741 |
P07197 |
0.63 |
|
P4HB |
5034 |
P07237 |
0.63 |
|
PNN |
5411 |
Q9H307 |
0.63 |
|
PTMA |
5757 |
P06454 |
0.63 |
|
SGTA |
6449 |
O43765 |
0.63 |
|
SHMT2 |
6472 |
P34897 |
0.63 |
|
SLC25A1 |
6576 |
P53007 |
0.63 |
|
TOP2B |
7155 |
Q02880 |
0.63 |
|
VWF |
7450 |
P04275 |
0.63 |
|
WARS |
7453 |
P23381 |
0.63 |
|
PABPN1 |
8106 |
Q86U42 |
0.63 |
|
SPARCL1 |
8404 |
Q14515 |
0.63 |
|
LMO4 |
8543 |
P61968 |
0.63 |
|
PIAS1 |
8554 |
O75925 |
0.63 |
|
DDX3Y |
8653 |
O15523 |
0.63 |
|
EIF3B |
8662 |
P55884 |
0.63 |
|
RABEP1 |
9135 |
Q15276 |
0.63 |
|
SF3A1 |
10291 |
Q15459 |
0.63 |
|
CCT7 |
10574 |
Q99832 |
0.63 |
|
IGF2BP2 |
10644 |
Q9Y6M1 |
0.63 |
|
CEP250 |
11190 |
Q9BV73 |
0.63 |
|
RPL35 |
11224 |
P42766 |
0.63 |
|
NACAD |
23148 |
O15069 |
0.63 |
|
MAPK8IP3 |
23162 |
Q9UPT6 |
0.63 |
|
SYNM |
23336 |
O15061 |
0.63 |
|
PSD3 |
23362 |
Q9NYI0 |
0.63 |
|
LARP1 |
23367 |
Q6PKG0 |
0.63 |
|
APPL1 |
26060 |
Q9UKG1 |
0.63 |
|
PABPC1 |
26986 |
P11940 |
0.63 |
|
HIPK2 |
28996 |
Q9H2X6 |
0.63 |
|
ANKRD11 |
29123 |
Q6UB99 |
0.63 |
|
DNTTIP2 |
30836 |
Q5QJE6 |
0.63 |
|
GAR1 |
54433 |
Q9NY12 |
0.63 |
|
PPP1R9A |
55607 |
Q9ULJ8 |
0.63 |
|
SYBU |
55638 |
Q9NX95 |
0.63 |
|
PNMAL2 |
57469 |
Q9ULN7 |
0.63 |
|
SIPA1L2 |
57568 |
Q9P2F8 |
0.63 |
|
EPS8L2 |
64787 |
Q9H6S3 |
0.63 |
|
ZNF655 |
79027 |
Q8N720 |
0.63 |
|
TNIP2 |
79155 |
Q8NFZ5 |
0.63 |
|
CHD9 |
80205 |
Q3L8U1 |
0.63 |
|
SRCIN1 |
80725 |
Q9C0H9 |
0.63 |
|
PPP1R9B |
84687 |
Q96SB3 |
0.63 |
|
TUBA1C |
84790 |
Q9BQE3 |
0.63 |
|
CIPC |
85457 |
Q9C0C6 |
0.63 |
|
CCDC155 |
147872 |
Q8N6L0 |
0.63 |
|
TTC14 |
151613 |
Q96N46 |
0.63 |
|
NIPAL4 |
348938 |
Q0D2K0 |
0.63 |
|
MYO18A |
399687 |
Q92614 |
0.63 |
|
CSNK2A1 |
1457 |
P68400 |
0.70 |
|
ILF2 |
3608 |
Q12905 |
0.82 |
|
RPL6 |
6128 |
Q02878 |
0.82 |
|
RPS3 |
6188 |
P23396 |
0.82 |
|
YWHAG |
7532 |
P61981 |
0.90 |
|
SLC25A10 |
1468 |
Q9UBX3 |
0.49 |
|
NLRP2 |
55655 |
Q9NX02 |
0.49 |
|
CDCA5 |
113130 |
Q96FF9 |
0.49 |
|
CD247 |
919 |
P20963 |
0.56 |
|
SUMO1 |
7341 |
P63165 |
0.56 |
|
BARD1 |
580 |
Q99728 |
0.63 |
|
BCL2L1 |
598 |
Q07817 |
0.63 |
|
C1QBP |
708 |
Q07021 |
0.63 |
|
CCNG1 |
900 |
P51959 |
0.63 |
|
CCNG2 |
901 |
Q16589 |
0.63 |
|
CCNT2 |
905 |
O60583 |
0.63 |
|
DDX5 |
1655 |
P17844 |
0.63 |
|
DHX9 |
1660 |
Q08211 |
0.63 |
|
ECT2 |
1894 |
Q9H8V3 |
0.63 |
|
ELAVL1 |
1994 |
Q15717 |
0.63 |
|
ELF1 |
1997 |
P32519 |
0.63 |
|
ESR1 |
2099 |
P03372 |
0.63 |
|
ESR2 |
2100 |
Q92731 |
0.63 |
|
EZH2 |
2146 |
Q15910 |
0.63 |
|
GRK5 |
2869 |
P34947 |
0.63 |
|
HIST1H1A |
3024 |
Q02539 |
0.63 |
|
IFI16 |
3428 |
Q16666 |
0.63 |
|
INSR |
3643 |
P06213 |
0.63 |
|
EIF3E |
3646 |
P60228 |
0.63 |
|
ITGA4 |
3676 |
P13612 |
0.63 |
|
JUN |
3725 |
P05412 |
0.63 |
|
MNDA |
4332 |
P41218 |
0.63 |
|
MYO10 |
4651 |
Q9HD67 |
0.63 |
|
NFX1 |
4799 |
Q12986 |
0.63 |
|
NTRK1 |
4914 |
P04629 |
0.63 |
|
PLXNB1 |
5364 |
O43157 |
0.63 |
|
PSMC1 |
5700 |
P62191 |
0.63 |
|
RNF2 |
6045 |
Q99496 |
0.63 |
|
RPS3A |
6189 |
P61247 |
0.63 |
|
RPS4X |
6191 |
P62701 |
0.63 |
|
RPS5 |
6193 |
P46782 |
0.63 |
|
RPS8 |
6202 |
P62241 |
0.63 |
|
RPS9 |
6203 |
P46781 |
0.63 |
|
RPS10 |
6204 |
P46783 |
0.63 |
|
RPS12 |
6206 |
P25398 |
0.63 |
|
RPS13 |
6207 |
P62277 |
0.63 |
|
RPS14 |
6208 |
P62263 |
0.63 |
|
RPS16 |
6217 |
P62249 |
0.63 |
|
RPS18 |
6222 |
P62269 |
0.63 |
|
RPS29 |
6235 |
P62273 |
0.63 |
|
SMPD1 |
6609 |
P17405 |
0.63 |
|
SOX2 |
6657 |
P48431 |
0.63 |
|
AURKA |
6790 |
O14965 |
0.63 |
|
SURF2 |
6835 |
Q15527 |
0.63 |
|
TNNT1 |
7138 |
P13805 |
0.63 |
|
TSG101 |
7251 |
Q99816 |
0.63 |
|
VCAM1 |
7412 |
P19320 |
0.63 |
|
YWHAH |
7533 |
Q04917 |
0.63 |
|
CUL5 |
8065 |
Q93034 |
0.63 |
|
CUL4B |
8450 |
Q13620 |
0.63 |
|
CUL3 |
8452 |
Q13618 |
0.63 |
|
CUL2 |
8453 |
Q13617 |
0.63 |
|
CUL1 |
8454 |
Q13616 |
0.63 |
|
EIF3A |
8661 |
Q14152 |
0.63 |
|
EIF3C |
8663 |
Q99613 |
0.63 |
|
NCOR2 |
9612 |
Q9Y618 |
0.63 |
|
KIAA0101 |
9768 |
Q15004 |
0.63 |
|
ARHGEF11 |
9826 |
O15085 |
0.63 |
|
HNRNPDL |
9987 |
O14979 |
0.63 |
|
EIF1B |
10289 |
O60739 |
0.63 |
|
IVNS1ABP |
10625 |
Q9Y6Y0 |
0.63 |
|
TCERG1 |
10915 |
O14776 |
0.63 |
|
CCNI |
10983 |
Q14094 |
0.63 |
|
COPS5 |
10987 |
Q92905 |
0.63 |
|
HNRNPUL1 |
11100 |
Q9BUJ2 |
0.63 |
|
GABARAP |
11337 |
O95166 |
0.63 |
|
GABARAPL2 |
11345 |
P60520 |
0.63 |
|
PAXIP1 |
22976 |
Q6ZW49 |
0.63 |
|
ZC3H3 |
23144 |
Q8IXZ2 |
0.63 |
|
VPS39 |
23339 |
Q96JC1 |
0.63 |
|
TARDBP |
23435 |
Q13148 |
0.63 |
|
SUZ12 |
23512 |
Q15022 |
0.63 |
|
MKRN1 |
23608 |
Q9UHC7 |
0.63 |
|
ANKRD1 |
27063 |
Q15327 |
0.63 |
|
EIF3K |
27335 |
Q9UBQ5 |
0.63 |
|
TRA2A |
29896 |
Q13595 |
0.63 |
|
ITSN2 |
50618 |
Q9NZM3 |
0.63 |
|
EIF3L |
51386 |
Q9Y262 |
0.63 |
|
SIRT7 |
51547 |
Q9NRC8 |
0.63 |
|
LUC7L2 |
51631 |
Q9Y383 |
0.63 |
|
POLE3 |
54107 |
Q9NRF9 |
0.63 |
|
LUC7L |
55692 |
Q9NQ29 |
0.63 |
|
PRR11 |
55771 |
Q96HE9 |
0.63 |
|
RIOK2 |
55781 |
Q9BVS4 |
0.63 |
|
CAND1 |
55832 |
Q86VP6 |
0.63 |
|
CTNNBL1 |
56259 |
Q8WYA6 |
0.63 |
|
NOL12 |
79159 |
Q9UGY1 |
0.63 |
|
LIN28A |
79727 |
Q9H9Z2 |
0.63 |
|
SNIP1 |
79753 |
Q8TAD8 |
0.63 |
|
NIFK |
84365 |
Q9BYG3 |
0.63 |
|
NEXN |
91624 |
Q0ZGT2 |
0.63 |
|
SRPK1 |
6732 |
Q96SB4 |
0.70 |
|
FOXL2 |
668 |
P58012 |
0.72 |
|
CLK3 |
1198 |
P49761 |
0.72 |
|
FOXG1 |
2290 |
P55316 |
0.72 |
|
HNRNPU |
3192 |
Q00839 |
0.72 |
|
CNOT2 |
4848 |
Q9NZN8 |
0.72 |
|
NPM1 |
4869 |
P06748 |
0.72 |
|
RPL10 |
6134 |
P27635 |
0.72 |
|
NOP56 |
10528 |
O00567 |
0.72 |
|
RRP1B |
23076 |
Q14684 |
0.72 |
|
FOXQ1 |
94234 |
Q9C009 |
0.72 |
|
HNRNPA1 |
3178 |
P09651 |
0.73 |
|
YWHAE |
7531 |
P62258 |
0.73 |
|
YBX1 |
4904 |
P67809 |
0.82 |
|
YWHAQ |
10971 |
P27348 |
0.88 |
|
YWHAB |
7529 |
P31946 |
0.90 |
|
YWHAZ |
7534 |
P63104 |
0.90 |