| Gene Symbol | U2SURP |
| Entrez ID | 23350 |
| Uniprot ID | O15042 |
| Description | U2 snRNP-associated SURP domain containing |
| Chromosomal Location | chr3: 142,964,497-143,060,546 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0006396 |
RNA processing |
Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. |
IEA |
|
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
IDA |
|
CC |
GO:0005654 |
nucleoplasm |
That part of the nuclear content other than the chromosomes or the nucleolus. |
IDA |
|
MF |
GO:0000166 |
nucleotide binding |
Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. |
IEA |
|
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
|
MF |
GO:0044822 |
poly(A) RNA binding |
Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases. |
IDA |
| Domain ID | Description |
|---|---|
|
IPR000061 |
SWAP/Surp |
|
IPR000504 |
RNA recognition motif domain |
|
IPR006569 |
CID domain |
|
IPR008942 |
ENTH/VHS |
|
IPR013170 |
mRNA splicing factor Cwf21 domain |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
|
hsa03040 |
Spliceosome |
KEGG |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
appendix |
glandular cells |
|
appendix |
lymphoid tissue |
|
breast |
glandular cells |
|
breast |
myoepithelial cells |
|
bronchus |
respiratory epithelial cells |
|
caudate |
neuronal cells |
|
cerebellum |
cells in molecular layer |
|
cerebellum |
Purkinje cells |
|
cerebral cortex |
neuronal cells |
|
cervix, uterine |
glandular cells |
|
cervix, uterine |
squamous epithelial cells |
|
colon |
glandular cells |
|
duodenum |
glandular cells |
|
endometrium |
glandular cells |
|
epididymis |
glandular cells |
|
esophagus |
squamous epithelial cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
heart muscle |
myocytes |
|
hippocampus |
glial cells |
|
hippocampus |
neuronal cells |
|
kidney |
cells in tubules |
|
lung |
macrophages |
|
nasopharynx |
respiratory epithelial cells |
|
oral mucosa |
squamous epithelial cells |
|
ovary |
follicle cells |
|
pancreas |
exocrine glandular cells |
|
placenta |
trophoblastic cells |
|
prostate |
glandular cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
seminal vesicle |
glandular cells |
|
skin |
keratinocytes |
|
skin |
melanocytes |
|
skin |
epidermal cells |
|
small intestine |
glandular cells |
|
soft tissue |
chondrocytes |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
testis |
Leydig cells |
|
thyroid gland |
glandular cells |
|
tonsil |
germinal center cells |
|
tonsil |
squamous epithelial cells |
|
urinary bladder |
urothelial cells |
|
vagina |
squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
15291743 |
Diao et al. |
2004 |
The molecular characteristics of polycystic ovary syndrome (PCOS) ovary defined by human ovary cDNA microarray |
|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
TBC1D4 |
9882 |
O60343 |
0.63 |
|
DDX42 |
11325 |
Q86XP3 |
0.63 |
|
TRA2A |
29896 |
Q13595 |
0.63 |
|
CTNNBL1 |
56259 |
Q8WYA6 |
0.63 |
|
RBM10 |
8241 |
P98175 |
0.76 |
|
RBM5 |
10181 |
P52756 |
0.76 |
|
LMNA |
4000 |
P02545 |
0.49 |
|
MFAP1 |
4236 |
P55081 |
0.49 |
|
SF3A1 |
10291 |
Q15459 |
0.49 |
|
CHERP |
10523 |
Q8IWX8 |
0.49 |
|
BARD1 |
580 |
Q99728 |
0.63 |
|
CDC5L |
988 |
Q99459 |
0.63 |
|
GRK5 |
2869 |
P34947 |
0.63 |
|
HSPA9 |
3313 |
P38646 |
0.63 |
|
JUN |
3725 |
P05412 |
0.63 |
|
RPSA |
3921 |
P08865 |
0.63 |
|
NTRK1 |
4914 |
P04629 |
0.63 |
|
RPA1 |
6117 |
P27694 |
0.63 |
|
RPA2 |
6118 |
P15927 |
0.63 |
|
RPA3 |
6119 |
P35244 |
0.63 |
|
RPS2 |
6187 |
P15880 |
0.63 |
|
RPS8 |
6202 |
P62241 |
0.63 |
|
TERT |
7015 |
O14746 |
0.63 |
|
SF1 |
7536 |
Q15637 |
0.63 |
|
ZRSR2 |
8233 |
Q15696 |
0.63 |
|
HIST1H3A |
8350 |
P68431 |
0.63 |
|
CUL3 |
8452 |
Q13618 |
0.63 |
|
CUL1 |
8454 |
Q13616 |
0.63 |
|
MDC1 |
9656 |
Q14676 |
0.63 |
|
CUL7 |
9820 |
Q14999 |
0.63 |
|
COPS5 |
10987 |
Q92905 |
0.63 |
|
GABARAP |
11337 |
O95166 |
0.63 |
|
SNW1 |
22938 |
Q13573 |
0.63 |
|
PAXIP1 |
22976 |
Q6ZW49 |
0.63 |
|
SSPO |
23145 |
A2VEC9 |
0.63 |
|
OBSL1 |
23363 |
O75147 |
0.63 |
|
TARDBP |
23435 |
Q13148 |
0.63 |
|
GABARAPL1 |
23710 |
Q9H0R8 |
0.63 |
|
DROSHA |
29102 |
Q9NRR4 |
0.63 |
|
DDX41 |
51428 |
Q9UJV9 |
0.63 |
|
SIRT7 |
51547 |
Q9NRC8 |
0.63 |
|
WWOX |
51741 |
Q9NZC7 |
0.63 |
|
MED9 |
55090 |
Q9NWA0 |
0.63 |
|
MED29 |
55588 |
Q9NX70 |
0.63 |
|
PRPF40A |
55660 |
O75400 |
0.63 |
|
CAND1 |
55832 |
Q86VP6 |
0.63 |
|
RBM17 |
84991 |
Q96I25 |
0.63 |
|
WDFY2 |
115825 |
Q96P53 |
0.63 |
|
MED19 |
219541 |
A0JLT2 |
0.63 |
|
ESR1 |
2099 |
P03372 |
0.67 |
|
MYC |
4609 |
P01106 |
0.72 |
|
MYO1C |
4641 |
O00159 |
0.72 |
|
SUMO2 |
6613 |
P61956 |
0.73 |
|
SF3A2 |
8175 |
Q15428 |
0.82 |