Gene Symbol | ATP11B |
Entrez ID | 23200 |
Uniprot ID | Q9Y2G3 |
Description | ATPase, class VI, type 11B |
Chromosomal Location | chr3: 182,793,500-182,921,635 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006811 |
ion transport |
The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
NAS |
BP |
GO:0015917 |
aminophospholipid transport |
The directed movement of aminophospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aminophospholipids contain phosphoric acid as a mono- or diester and an amino (NH2) group. |
TAS |
BP |
GO:0034220 |
ion transmembrane transport |
A process in which an ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. |
TAS |
BP |
GO:0045332 |
phospholipid translocation |
The movement of a phospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet. |
NAS |
CC |
GO:0005637 |
nuclear inner membrane |
The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope. |
NAS |
CC |
GO:0005769 |
early endosome |
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways. |
IEA |
CC |
GO:0005783 |
endoplasmic reticulum |
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
IDA |
CC |
GO:0005794 |
Golgi apparatus |
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions. |
IEA |
CC |
GO:0005886 |
plasma membrane |
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
IBA|TAS |
CC |
GO:0016020 |
membrane |
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
IDA |
CC |
GO:0016021 |
integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IEA |
CC |
GO:0055037 |
recycling endosome |
An organelle consisting of a network of tubules that functions in targeting molecules, such as receptors transporters and lipids, to the plasma membrane. |
IDA |
CC |
GO:0055038 |
recycling endosome membrane |
The lipid bilayer surrounding a recycling endosome. |
IEA |
MF |
GO:0000287 |
magnesium ion binding |
Interacting selectively and non-covalently with magnesium (Mg) ions. |
IEA |
MF |
GO:0004012 |
phospholipid-translocating ATPase activity |
Catalysis of the movement of phospholipids from one membrane bilayer leaflet to the other, driven by the hydrolysis of ATP. |
TAS |
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
MF |
GO:0005524 |
ATP binding |
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
IEA |
MF |
GO:0015075 |
ion transmembrane transporter activity |
Enables the transfer of an ion from one side of a membrane to the other. |
NAS |
Domain ID | Description |
---|---|
IPR001757 |
P-type ATPase |
IPR006539 |
P-type ATPase, subfamily IV |
IPR008250 |
P-type ATPase, A domain |
IPR018303 |
P-type ATPase, phosphorylation site |
IPR023214 |
HAD-like domain |
IPR023299 |
P-type ATPase, cytoplasmic domain N |
IPR030362 |
Probable phospholipid-transporting ATPase IF |
IPR032630 |
P-type ATPase, C-terminal |
IPR032631 |
P-type ATPase, N-terminal |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
TMEM30A |
55754 |
Q9NV96 |
0.63 |