BP

GO:0006351

transcription, DNA-templated

The cellular synthesis of RNA on a template of DNA.

IEA

BP

GO:0006355

regulation of transcription, DNA-templated

Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

IEA

BP

GO:0010977

negative regulation of neuron projection development

Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).

IDA

BP

GO:0030177

positive regulation of Wnt signaling pathway

Any process that activates or increases the frequency, rate or extent of Wnt signal transduction.

IDA

BP

GO:0030336

negative regulation of cell migration

Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.

IMP

BP

GO:0030837

negative regulation of actin filament polymerization

Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization.

IDA

BP

GO:0035024

negative regulation of Rho protein signal transduction

Any process that stops, prevents, or reduces the frequency, rate or extent of Rho protein signal transduction.

IMP

BP

GO:0035413

positive regulation of catenin import into nucleus

Any process that increases the rate, frequency or extent of the directed movement of a catenin protein from the cytoplasm into the nucleus.

IMP

BP

GO:0046627

negative regulation of insulin receptor signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling.

IMP

BP

GO:0090303

positive regulation of wound healing

Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.

IMP

BP

GO:1900025

negative regulation of substrate adhesion-dependent cell spreading

Any process that stops, prevents or reduces the frequency, rate or extent of substrate adhesion-dependent cell spreading.

IDA

BP

GO:1900028

negative regulation of ruffle assembly

Any process that stops, prevents or reduces the frequency, rate or extent of ruffle assembly.

IDA

BP

GO:2000114

regulation of establishment of cell polarity

Any process that modulates the frequency, rate or extent of establishment of cell polarity.

IMP

BP

GO:2000393

negative regulation of lamellipodium morphogenesis

Any process that stops, prevents or reduces the frequency, rate or extent of lamellipodium morphogenesis.

IDA

CC

GO:0005634

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

IEA

CC

GO:0005737

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

IEA

CC

GO:0005886

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

IDA

CC

GO:0032587

ruffle membrane

The portion of the plasma membrane surrounding a ruffle.

IDA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0008013

beta-catenin binding

Interacting selectively and non-covalently with the beta subunit of the catenin complex.

IDA