Gene Symbol | RRP1B |
Entrez ID | 23076 |
Uniprot ID | Q14684 |
Description | ribosomal RNA processing 1B |
Chromosomal Location | chr21: 43,659,548-43,696,079 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006364 |
rRNA processing |
Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. |
IBA |
BP |
GO:0010923 |
negative regulation of phosphatase activity |
Any process that decreases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate. |
IDA |
CC |
GO:0000791 |
euchromatin |
A dispersed and relatively uncompacted form of chromatin. |
IEA |
CC |
GO:0000792 |
heterochromatin |
A compact and highly condensed form of chromatin. |
IEA |
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
IDA |
CC |
GO:0005730 |
nucleolus |
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
IDA |
CC |
GO:0005829 |
cytosol |
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
IDA |
CC |
GO:0030687 |
preribosome, large subunit precursor |
A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit. |
IBA |
CC |
GO:0030688 |
preribosome, small subunit precursor |
A preribosomal complex consisting of 20S pre-rRNA, ribosomal proteins including late-associating small subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic small ribosomal subunit. |
IEA |
MF |
GO:0044822 |
poly(A) RNA binding |
Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases. |
IDA |
Domain ID | Description |
---|---|
IPR010301 |
Nucleolar, Nop52 |
UMLS CUI | UMLS Term |
---|---|
C0341106 |
Eosinophilic Esophagitis |
Tissue | Cell Type |
---|---|
adrenal gland |
glandular cells |
breast |
glandular cells |
bronchus |
respiratory epithelial cells |
cerebellum |
cells in granular layer |
cerebellum |
cells in molecular layer |
cerebellum |
Purkinje cells |
cerebral cortex |
neuronal cells |
cervix, uterine |
glandular cells |
cervix, uterine |
squamous epithelial cells |
endometrium |
glandular cells |
esophagus |
squamous epithelial cells |
fallopian tube |
glandular cells |
gallbladder |
glandular cells |
hippocampus |
glial cells |
kidney |
cells in tubules |
nasopharynx |
respiratory epithelial cells |
placenta |
decidual cells |
placenta |
trophoblastic cells |
rectum |
glandular cells |
salivary gland |
glandular cells |
skeletal muscle |
myocytes |
skin |
epidermal cells |
testis |
cells in seminiferous ducts |
thyroid gland |
glandular cells |
tonsil |
squamous epithelial cells |
urinary bladder |
urothelial cells |
vagina |
squamous epithelial cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
SRSF1 |
6426 |
Q07955 |
0.63 |
SRSF6 |
6431 |
Q13247 |
0.63 |
LSM1 |
27257 |
O15116 |
0.63 |
CSNK2A1 |
1457 |
P68400 |
0.70 |
PARP1 |
142 |
P09874 |
0.72 |
IGKC |
3514 |
P01834 |
0.72 |
ILF3 |
3609 |
Q12906 |
0.72 |
NCL |
4691 |
P19338 |
0.72 |
RPL10A |
4736 |
P62906 |
0.72 |
NPM1 |
4869 |
P06748 |
0.72 |
RPL4 |
6124 |
P36578 |
0.72 |
RPL5 |
6125 |
P46777 |
0.72 |
RPLP0 |
6175 |
P05388 |
0.72 |
TOP1 |
7150 |
P11387 |
0.72 |
CUBN |
8029 |
O60494 |
0.72 |
YBX3 |
8531 |
P16989 |
0.72 |
PRPF4B |
8899 |
Q13523 |
0.72 |
H1FX |
8971 |
Q92522 |
0.72 |
DDX21 |
9188 |
Q9NR30 |
0.72 |
ALYREF |
10189 |
Q86V81 |
0.72 |
RRP1B |
23076 |
Q14684 |
0.72 |
LARP1 |
23367 |
Q6PKG0 |
0.72 |
SDF2L1 |
23753 |
Q9HCN8 |
0.72 |
RSL1D1 |
26156 |
O76021 |
0.72 |
IGKV2-40 |
28916 |
N/A |
0.72 |
LUC7L2 |
51631 |
Q9Y383 |
0.72 |
LUC7L3 |
51747 |
O95232 |
0.72 |
SLC22A11 |
55867 |
Q9NSA0 |
0.72 |
HNRNPA1 |
3178 |
P09651 |
0.82 |
NUP107 |
57122 |
P57740 |
0.49 |
SRPK2 |
6733 |
P78362 |
0.52 |
TRIM28 |
10155 |
Q13263 |
0.52 |
CBX5 |
23468 |
P45973 |
0.52 |
ESR2 |
2100 |
Q92731 |
0.55 |
SUMO1 |
7341 |
P63165 |
0.56 |
ELAVL1 |
1994 |
Q15717 |
0.63 |
IFI16 |
3428 |
Q16666 |
0.63 |
ILF2 |
3608 |
Q12905 |
0.63 |
JUN |
3725 |
P05412 |
0.63 |
MNDA |
4332 |
P41218 |
0.63 |
MPG |
4350 |
P29372 |
0.63 |
MYC |
4609 |
P01106 |
0.63 |
NTRK1 |
4914 |
P04629 |
0.63 |
PPP1R3A |
5506 |
Q16821 |
0.63 |
RNF2 |
6045 |
Q99496 |
0.63 |
ABCE1 |
6059 |
P61221 |
0.63 |
SUMO2 |
6613 |
P61956 |
0.63 |
TARBP2 |
6895 |
Q15633 |
0.63 |
TP53 |
7157 |
P04637 |
0.63 |
CUL3 |
8452 |
Q13618 |
0.63 |
RPL14 |
9045 |
P50914 |
0.63 |
KIAA0101 |
9768 |
Q15004 |
0.63 |
CUL7 |
9820 |
Q14999 |
0.63 |
SMNDC1 |
10285 |
O75940 |
0.63 |
OBSL1 |
23363 |
O75147 |
0.63 |
SIRT7 |
51547 |
Q9NRC8 |
0.63 |
PINX1 |
54984 |
Q96BK5 |
0.63 |
LYAR |
55646 |
Q9NX58 |
0.63 |
CCDC8 |
83987 |
Q9H0W5 |
0.63 |
ESR1 |
2099 |
P03372 |
0.67 |
APOA1 |
335 |
P02647 |
0.72 |
MAPK14 |
1432 |
Q16539 |
0.72 |
CSNK2A2 |
1459 |
P19784 |
0.72 |
HDGF |
3068 |
P51858 |
0.72 |
HNRNPU |
3192 |
Q00839 |
0.72 |
SORT1 |
6272 |
Q99523 |
0.72 |
BAG6 |
7917 |
P46379 |
0.72 |
SRPK3 |
26576 |
Q9UPE1 |
0.72 |
PPP1CC |
5501 |
P36873 |
0.87 |
PPP1CA |
5499 |
P62136 |
0.89 |