| Gene Symbol | SEPHS1 |
| Entrez ID | 22929 |
| Uniprot ID | P49903 |
| Description | selenophosphate synthetase 1 |
| Chromosomal Location | chr10: 13,317,424-13,348,298 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0006464 |
cellular protein modification process |
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). |
TAS |
|
BP |
GO:0016310 |
phosphorylation |
The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. |
IEA |
|
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
IEA |
|
CC |
GO:0005886 |
plasma membrane |
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
IEA |
|
CC |
GO:0031965 |
nuclear membrane |
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space. |
IEA |
|
MF |
GO:0004756 |
selenide, water dikinase activity |
Catalysis of the reaction: ATP + H(2)O + hydrogen selenide = AMP + 3 H(+) + phosphate + selenophosphorate. |
IEA |
|
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
|
MF |
GO:0005524 |
ATP binding |
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
IEA |
|
MF |
GO:0005525 |
GTP binding |
Interacting selectively and non-covalently with GTP, guanosine triphosphate. |
TAS |
|
MF |
GO:0042802 |
identical protein binding |
Interacting selectively and non-covalently with an identical protein or proteins. |
IPI |
| Domain ID | Description |
|---|---|
|
IPR004536 |
Selenophosphate synthetase |
|
IPR010918 |
AIR synthase-related protein, C-terminal domain |
|
IPR016188 |
PurM-like, N-terminal domain |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
|
hsa00450 |
Selenocompound metabolism |
KEGG |
|
hsa01100 |
Metabolic pathways |
KEGG |
|
WP28 |
Selenium Metabolism and Selenoproteins |
WikiPathways |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
breast |
adipocytes |
|
breast |
glandular cells |
|
breast |
myoepithelial cells |
|
bronchus |
respiratory epithelial cells |
|
cerebral cortex |
neuronal cells |
|
cervix, uterine |
glandular cells |
|
cervix, uterine |
squamous epithelial cells |
|
colon |
endothelial cells |
|
colon |
glandular cells |
|
duodenum |
glandular cells |
|
endometrium |
glandular cells |
|
endometrium |
cells in endometrial stroma |
|
epididymis |
glandular cells |
|
esophagus |
squamous epithelial cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
nasopharynx |
respiratory epithelial cells |
|
oral mucosa |
squamous epithelial cells |
|
pancreas |
exocrine glandular cells |
|
placenta |
decidual cells |
|
placenta |
trophoblastic cells |
|
prostate |
glandular cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
seminal vesicle |
glandular cells |
|
skin |
fibroblasts |
|
skin |
keratinocytes |
|
skin |
Langerhans |
|
skin |
melanocytes |
|
skin |
epidermal cells |
|
small intestine |
glandular cells |
|
soft tissue |
adipocytes |
|
soft tissue |
fibroblasts |
|
soft tissue |
peripheral nerve |
|
soft tissue |
chondrocytes |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
testis |
Leydig cells |
|
thyroid gland |
glandular cells |
|
tonsil |
non-germinal center cells |
|
urinary bladder |
urothelial cells |
|
vagina |
squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
ACADS |
35 |
P16219 |
0.49 |
|
CRKL |
1399 |
P46109 |
0.49 |
|
G6PD |
2539 |
P11413 |
0.49 |
|
HSPB1 |
3315 |
P04792 |
0.49 |
|
SEC13 |
6396 |
P55735 |
0.49 |
|
TPD52 |
7163 |
P55327 |
0.49 |
|
TUFM |
7284 |
P49411 |
0.49 |
|
PDCD6 |
10016 |
O75340 |
0.49 |
|
SUGT1 |
10910 |
Q9Y2Z0 |
0.49 |
|
XPO7 |
23039 |
Q9UIA9 |
0.49 |
|
RTCB |
51493 |
Q9Y3I0 |
0.49 |
|
DDX19A |
55308 |
Q9NUU7 |
0.49 |
|
MCFD2 |
90411 |
Q8NI22 |
0.49 |
|
WDR12 |
55759 |
Q9GZL7 |
0.59 |
|
CRMP1 |
1400 |
Q14194 |
0.63 |
|
C14orf1 |
11161 |
Q9UKR5 |
0.63 |
|
QRICH1 |
54870 |
Q2TAL8 |
0.63 |
|
SLC35F6 |
54978 |
Q8N357 |
0.63 |
|
IGSF21 |
84966 |
Q96ID5 |
0.63 |
|
DEPDC7 |
91614 |
Q96QD5 |
0.63 |
|
GBP7 |
388646 |
Q8N8V2 |
0.63 |
|
ZBTB25 |
7597 |
P24278 |
0.73 |
|
SEPHS1 |
22929 |
P49903 |
0.74 |
|
CLIC1 |
1192 |
O00299 |
0.49 |
|
ECH1 |
1891 |
Q13011 |
0.49 |
|
FDPS |
2224 |
P14324 |
0.49 |
|
PTPRF |
5792 |
P10586 |
0.49 |
|
UMPS |
7372 |
P11172 |
0.49 |
|
XPO1 |
7514 |
O14980 |
0.49 |
|
COPS2 |
9318 |
P61201 |
0.49 |
|
AHCYL1 |
10768 |
O43865 |
0.49 |
|
DIS3 |
22894 |
Q9Y2L1 |
0.49 |
|
HYPK |
25764 |
Q9NX55 |
0.49 |
|
CLIC4 |
25932 |
Q9Y696 |
0.49 |
|
REXO2 |
25996 |
Q9Y3B8 |
0.49 |
|
MAT2B |
27430 |
Q9NZL9 |
0.49 |
|
PPIL3 |
53938 |
Q9H2H8 |
0.49 |
|
PIPSL |
266971 |
A2A3N6 |
0.49 |
|
GART |
2618 |
P22102 |
0.59 |
|
PFAS |
5198 |
O15067 |
0.59 |
|
PUM1 |
9698 |
Q14671 |
0.59 |
|
CNN3 |
1266 |
Q15417 |
0.63 |
|
ELAVL1 |
1994 |
Q15717 |
0.63 |
|
GBP2 |
2634 |
P32456 |
0.63 |
|
SAT1 |
6303 |
P21673 |
0.63 |
|
SOX2 |
6657 |
P48431 |
0.63 |
|
CUL3 |
8452 |
Q13618 |
0.63 |
|
TNFRSF10D |
8793 |
Q9UBN6 |
0.63 |
|
UNC119 |
9094 |
Q13432 |
0.63 |
|
EIF1B |
10289 |
O60739 |
0.63 |
|
SPACA9 |
11092 |
Q96E40 |
0.63 |
|
CDCA4 |
55038 |
Q9BXL8 |
0.63 |
|
CCDC130 |
81576 |
P13994 |
0.63 |
|
TAS2R41 |
259287 |
P59536 |
0.63 |