Protein Description

Gene Symbol CLSTN1
Entrez ID 22883
Uniprot ID O94985
Description calsyntenin 1
Chromosomal Location chr1: 9,729,026-9,824,526
Ontology GO ID GO Term Definition Evidence

BP

GO:0001558

regulation of cell growth

Any process that modulates the frequency, rate, extent or direction of cell growth.

IEA

BP

GO:0007155

cell adhesion

The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.

TAS

BP

GO:0007156

homophilic cell adhesion via plasma membrane adhesion molecules

The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell.

IEA

BP

GO:0050806

positive regulation of synaptic transmission

Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.

IEA

BP

GO:0051965

positive regulation of synapse assembly

Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.

IEA

CC

GO:0000139

Golgi membrane

The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

IEA

CC

GO:0005634

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

IEA

CC

GO:0005789

endoplasmic reticulum membrane

The lipid bilayer surrounding the endoplasmic reticulum.

IEA

CC

GO:0009986

cell surface

The external part of the cell wall and/or plasma membrane.

IEA

CC

GO:0016021

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

IEA

CC

GO:0030054

cell junction

A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.

IEA

CC

GO:0042995

cell projection

A prolongation or process extending from a cell, e.g. a flagellum or axon.

IEA

CC

GO:0045211

postsynaptic membrane

A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.

IEA

CC

GO:0070062

extracellular exosome

A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.

IDA

MF

GO:0001540

beta-amyloid binding

Interacting selectively and non-covalently with beta-amyloid peptide/protein and/or its precursor.

IDA

MF

GO:0005509

calcium ion binding

Interacting selectively and non-covalently with calcium ions (Ca2+).

IEA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0019894

kinesin binding

Interacting selectively and non-covalently and stoichiometrically with kinesin, a member of a superfamily of microtubule-based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation.

IPI

MF

GO:0042988

X11-like protein binding

Interacting selectively and non-covalently with X11-like protein, a neuron-specific adaptor protein.

IPI

Domain ID Description

IPR002126

Cadherin

IPR013320

Concanavalin A-like lectin/glucanase domain

IPR015919

Cadherin-like

IPR026914

Calsyntenin

No pathways found.

No diseases found.

Tissue Cell Type

cerebellum

cells in granular layer

cerebellum

Purkinje cells

cerebral cortex

neuronal cells

cerebral cortex

neuropil

colon

glandular cells

pancreas

exocrine glandular cells

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol Entrez ID Uniprot ID Score

KIF2A

3796

O00139

0.52

PRNP

5621

P04156

0.52

MDM2

4193

Q00987

0.56

FLNB

2317

O75369

0.63

FLNC

2318

Q14315

0.63

MCM3AP

8888

O60318

0.63

TRIP12

9320

Q14669

0.63

SETDB1

9869

Q15047

0.63

TOPBP1

11073

Q92547

0.63

CLSTN1

22883

O94985

0.63

KLC2

64837

Q9H0B6

0.65

KLC1

3831

Q07866

0.67

PSEN1

5663

P49768

0.72

APBB1

322

O00213

0.76

APP

351

P05067

0.82

APBA2

321

Q99767

0.89

GTF2F2

2963

P13984

0.49

PAX8

7849

Q06710

0.49

COL17A1

1308

Q9UMD9

0.63

MYC

4609

P01106

0.63

SLK

9748

Q9H2G2

0.63

CD96

10225

P40200

0.63

BAHCC1

57597

Q9P281

0.63

CHST8

64377

Q9H2A9

0.63

PVRIG

79037

Q6DKI7

0.63

TM2D3

80213

Q9BRN9

0.63

GINM1

116254

Q9NU53

0.63