Gene Symbol | CLSTN1 |
Entrez ID | 22883 |
Uniprot ID | O94985 |
Description | calsyntenin 1 |
Chromosomal Location | chr1: 9,729,026-9,824,526 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0001558 |
regulation of cell growth |
Any process that modulates the frequency, rate, extent or direction of cell growth. |
IEA |
BP |
GO:0007155 |
cell adhesion |
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. |
TAS |
BP |
GO:0007156 |
homophilic cell adhesion via plasma membrane adhesion molecules |
The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell. |
IEA |
BP |
GO:0050806 |
positive regulation of synaptic transmission |
Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. |
IEA |
BP |
GO:0051965 |
positive regulation of synapse assembly |
Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse. |
IEA |
CC |
GO:0000139 |
Golgi membrane |
The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
IEA |
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
IEA |
CC |
GO:0005789 |
endoplasmic reticulum membrane |
The lipid bilayer surrounding the endoplasmic reticulum. |
IEA |
CC |
GO:0009986 |
cell surface |
The external part of the cell wall and/or plasma membrane. |
IEA |
CC |
GO:0016021 |
integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IEA |
CC |
GO:0030054 |
cell junction |
A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix. |
IEA |
CC |
GO:0042995 |
cell projection |
A prolongation or process extending from a cell, e.g. a flagellum or axon. |
IEA |
CC |
GO:0045211 |
postsynaptic membrane |
A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane. |
IEA |
CC |
GO:0070062 |
extracellular exosome |
A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. |
IDA |
MF |
GO:0001540 |
beta-amyloid binding |
Interacting selectively and non-covalently with beta-amyloid peptide/protein and/or its precursor. |
IDA |
MF |
GO:0005509 |
calcium ion binding |
Interacting selectively and non-covalently with calcium ions (Ca2+). |
IEA |
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
MF |
GO:0019894 |
kinesin binding |
Interacting selectively and non-covalently and stoichiometrically with kinesin, a member of a superfamily of microtubule-based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation. |
IPI |
MF |
GO:0042988 |
X11-like protein binding |
Interacting selectively and non-covalently with X11-like protein, a neuron-specific adaptor protein. |
IPI |
Domain ID | Description |
---|---|
IPR002126 |
Cadherin |
IPR013320 |
Concanavalin A-like lectin/glucanase domain |
IPR015919 |
Cadherin-like |
IPR026914 |
Calsyntenin |
Tissue | Cell Type |
---|---|
cerebellum |
cells in granular layer |
cerebellum |
Purkinje cells |
cerebral cortex |
neuronal cells |
cerebral cortex |
neuropil |
colon |
glandular cells |
pancreas |
exocrine glandular cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
KIF2A |
3796 |
O00139 |
0.52 |
PRNP |
5621 |
P04156 |
0.52 |
MDM2 |
4193 |
Q00987 |
0.56 |
FLNB |
2317 |
O75369 |
0.63 |
FLNC |
2318 |
Q14315 |
0.63 |
MCM3AP |
8888 |
O60318 |
0.63 |
TRIP12 |
9320 |
Q14669 |
0.63 |
SETDB1 |
9869 |
Q15047 |
0.63 |
TOPBP1 |
11073 |
Q92547 |
0.63 |
CLSTN1 |
22883 |
O94985 |
0.63 |
KLC2 |
64837 |
Q9H0B6 |
0.65 |
KLC1 |
3831 |
Q07866 |
0.67 |
PSEN1 |
5663 |
P49768 |
0.72 |
APBB1 |
322 |
O00213 |
0.76 |
APP |
351 |
P05067 |
0.82 |
APBA2 |
321 |
Q99767 |
0.89 |
GTF2F2 |
2963 |
P13984 |
0.49 |
PAX8 |
7849 |
Q06710 |
0.49 |
COL17A1 |
1308 |
Q9UMD9 |
0.63 |
MYC |
4609 |
P01106 |
0.63 |
SLK |
9748 |
Q9H2G2 |
0.63 |
CD96 |
10225 |
P40200 |
0.63 |
BAHCC1 |
57597 |
Q9P281 |
0.63 |
CHST8 |
64377 |
Q9H2A9 |
0.63 |
PVRIG |
79037 |
Q6DKI7 |
0.63 |
TM2D3 |
80213 |
Q9BRN9 |
0.63 |
GINM1 |
116254 |
Q9NU53 |
0.63 |