Gene Symbol | COG2 |
Entrez ID | 22796 |
Uniprot ID | Q14746 |
Description | component of oligomeric golgi complex 2 |
Chromosomal Location | chr1: 230,642,489-230,693,982 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006888 |
ER to Golgi vesicle-mediated transport |
The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi. |
TAS |
BP |
GO:0006891 |
intra-Golgi vesicle-mediated transport |
The directed movement of substances within the Golgi, mediated by small transport vesicles. These either fuse with the cis-Golgi or with each other to form the membrane stacks known as the cis-Golgi reticulum (network). |
IMP |
BP |
GO:0007030 |
Golgi organization |
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus. |
IMP |
BP |
GO:0015031 |
protein transport |
The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
IEA |
CC |
GO:0000139 |
Golgi membrane |
The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
TAS |
CC |
GO:0005795 |
Golgi stack |
The set of thin, flattened membrane-bounded compartments, called cisternae, that form the central portion of the Golgi complex. The stack usually comprises cis, medial, and trans cisternae; the cis- and trans-Golgi networks are not considered part of the stack. |
IDA |
CC |
GO:0005829 |
cytosol |
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
IEA |
CC |
GO:0017119 |
Golgi transport complex |
A multisubunit tethering complex of the CATCHR family (complexes associated with tethering containing helical rods) that has a role in tethering vesicles to the Golgi prior to fusion. In yeast, this complex is called the Sec34/35 complex and is composed of eight subunits (Sec34p, Sec35p, Dor1p, Cod1p, Cod2p, Cod3p, Cod4p, and Cod5p). In mammals the subunits are named COG1-8. |
IDA|IMP |
CC |
GO:0032588 |
trans-Golgi network membrane |
The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network. |
TAS |
MF |
GO:0008565 |
protein transporter activity |
Enables the directed movement of proteins into, out of or within a cell, or between cells. |
IMP |
MF |
GO:0032403 |
protein complex binding |
Interacting selectively and non-covalently with any protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IEA |
Domain ID | Description |
---|---|
IPR009316 |
COG complex component, COG2 |
IPR024602 |
Conserved oligomeric Golgi complex, subunit 2, N-terminal |
IPR024603 |
COG complex component, COG2, C-terminal |
Database Name |
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DISEASES |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
COG5 |
10466 |
Q9UP83 |
0.59 |
COG6 |
57511 |
Q9Y2V7 |
0.59 |
COG8 |
84342 |
Q96MW5 |
0.59 |
COG7 |
91949 |
P83436 |
0.59 |
MTUS2 |
23281 |
Q5JR59 |
0.63 |
ATP6V1A |
523 |
P38606 |
0.49 |
COG1 |
9382 |
Q8WTW3 |
0.59 |
BSG |
682 |
P35613 |
0.63 |
NTRK1 |
4914 |
P04629 |
0.63 |
SCN2B |
6327 |
O60939 |
0.63 |
VSIG2 |
23584 |
Q96IQ7 |
0.63 |
CA14 |
23632 |
Q9ULX7 |
0.63 |
CD274 |
29126 |
Q9NZQ7 |
0.63 |
COMTD1 |
118881 |
Q86VU5 |
0.63 |
TEKT4 |
150483 |
Q8WW24 |
0.63 |
HNRNPD |
3184 |
Q14103 |
0.72 |
MAPK8 |
5599 |
P45983 |
0.72 |
NUP58 |
9818 |
Q9BVL2 |
0.72 |
RNASEH2A |
10535 |
O75792 |
0.72 |
COG4 |
25839 |
Q9H9E3 |
0.89 |
COG3 |
83548 |
Q96JB2 |
0.90 |