Protein Description

Gene Symbol COG2
Entrez ID 22796
Uniprot ID Q14746
Description component of oligomeric golgi complex 2
Chromosomal Location chr1: 230,642,489-230,693,982
Ontology GO ID GO Term Definition Evidence

BP

GO:0006888

ER to Golgi vesicle-mediated transport

The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.

TAS

BP

GO:0006891

intra-Golgi vesicle-mediated transport

The directed movement of substances within the Golgi, mediated by small transport vesicles. These either fuse with the cis-Golgi or with each other to form the membrane stacks known as the cis-Golgi reticulum (network).

IMP

BP

GO:0007030

Golgi organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus.

IMP

BP

GO:0015031

protein transport

The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

IEA

CC

GO:0000139

Golgi membrane

The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

TAS

CC

GO:0005795

Golgi stack

The set of thin, flattened membrane-bounded compartments, called cisternae, that form the central portion of the Golgi complex. The stack usually comprises cis, medial, and trans cisternae; the cis- and trans-Golgi networks are not considered part of the stack.

IDA

CC

GO:0005829

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

IEA

CC

GO:0017119

Golgi transport complex

A multisubunit tethering complex of the CATCHR family (complexes associated with tethering containing helical rods) that has a role in tethering vesicles to the Golgi prior to fusion. In yeast, this complex is called the Sec34/35 complex and is composed of eight subunits (Sec34p, Sec35p, Dor1p, Cod1p, Cod2p, Cod3p, Cod4p, and Cod5p). In mammals the subunits are named COG1-8.

IDA|IMP

CC

GO:0032588

trans-Golgi network membrane

The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network.

TAS

MF

GO:0008565

protein transporter activity

Enables the directed movement of proteins into, out of or within a cell, or between cells.

IMP

MF

GO:0032403

protein complex binding

Interacting selectively and non-covalently with any protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IEA

Domain ID Description

IPR009316

COG complex component, COG2

IPR024602

Conserved oligomeric Golgi complex, subunit 2, N-terminal

IPR024603

COG complex component, COG2, C-terminal

No pathways found.

No diseases found.

No tissues found.

Database Name

DISEASES

No sources found.

Gene Symbol Entrez ID Uniprot ID Score

COG5

10466

Q9UP83

0.59

COG6

57511

Q9Y2V7

0.59

COG8

84342

Q96MW5

0.59

COG7

91949

P83436

0.59

MTUS2

23281

Q5JR59

0.63

ATP6V1A

523

P38606

0.49

COG1

9382

Q8WTW3

0.59

BSG

682

P35613

0.63

NTRK1

4914

P04629

0.63

SCN2B

6327

O60939

0.63

VSIG2

23584

Q96IQ7

0.63

CA14

23632

Q9ULX7

0.63

CD274

29126

Q9NZQ7

0.63

COMTD1

118881

Q86VU5

0.63

TEKT4

150483

Q8WW24

0.63

HNRNPD

3184

Q14103

0.72

MAPK8

5599

P45983

0.72

NUP58

9818

Q9BVL2

0.72

RNASEH2A

10535

O75792

0.72

COG4

25839

Q9H9E3

0.89

COG3

83548

Q96JB2

0.90