Gene Symbol | MGAT4B |
Entrez ID | 11282 |
Uniprot ID | Q9UQ53 |
Description | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B |
Chromosomal Location | chr5: 179,797,597-179,806,952 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006491 |
N-glycan processing |
The conversion of N-linked glycan (N = nitrogen) structures from the initially transferred oligosaccharide to a mature form, by the actions of glycosidases and glycosyltransferases. The early processing steps are conserved and play roles in glycoprotein folding and trafficking. |
TAS |
CC |
GO:0000139 |
Golgi membrane |
The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
TAS |
CC |
GO:0016021 |
integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IEA |
MF |
GO:0008454 |
alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity |
Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + (N-acetyl-beta-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,4-(N-acetyl-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R. |
TAS |
MF |
GO:0046872 |
metal ion binding |
Interacting selectively and non-covalently with any metal ion. |
IEA |
Domain ID | Description |
---|---|
IPR006759 |
Glycosyl transferase family 54 |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa00510 |
N-Glycan biosynthesis |
KEGG |
hsa01100 |
Metabolic pathways |
KEGG |
Tissue | Cell Type |
---|---|
kidney |
cells in tubules |
placenta |
trophoblastic cells |
spleen |
cells in red pulp |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
SLC26A2 |
1836 |
P50443 |
0.49 |
UQCRFS1 |
7386 |
P47985 |
0.49 |
VDAC1 |
7416 |
P21796 |
0.49 |
SYNJ2BP |
55333 |
P57105 |
0.49 |
SFXN2 |
118980 |
Q96NB2 |
0.49 |
ATP6V0A1 |
535 |
Q93050 |
0.63 |
HBB |
3043 |
P68871 |
0.63 |
LRSAM1 |
90678 |
Q6UWE0 |
0.73 |
PLAUR |
5329 |
Q03405 |
0.63 |