PCOSBase

Protein Description

Gene Symbol	RASSF8
Entrez ID	11228
Uniprot ID	Q8NHQ8
Description	Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
Chromosomal Location	chr12: 25,959,029-26,079,892

Ontology	GO ID	GO Term	Definition	Evidence
BP	GO:0007165	signal transduction	The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.	IEA
BP	GO:0034334	adherens junction maintenance	The maintenance of an adherens junction. An adherens junction is a cell junction at which the cytoplasmic face of the plasma membrane is attached to actin filaments.	IEA

Domain ID	Description
IPR000159	Ras-associating (RA) domain
IPR029071	Ubiquitin-related domain
IPR033593	N-terminal RASSF family
IPR033632	Ras association domain-containing protein 8

UMLS CUI	UMLS Term
C0149925	Small Cell Carcinoma Of Lung

Tissue	Cell Type
adrenal gland	glandular cells
appendix	glandular cells
cerebellum	cells in molecular layer
cerebellum	Purkinje cells
cerebral cortex	neuronal cells
colon	glandular cells
duodenum	glandular cells
endometrium	glandular cells
esophagus	squamous epithelial cells
nasopharynx	respiratory epithelial cells
pancreas	exocrine glandular cells
placenta	trophoblastic cells
rectum	glandular cells
salivary gland	glandular cells
skin	fibroblasts
skin	keratinocytes
skin	Langerhans
skin	melanocytes
skin	epidermal cells
small intestine	glandular cells
smooth muscle	smooth muscle cells
soft tissue	fibroblasts
stomach	glandular cells
thyroid gland	glandular cells

Pubmed ID	Author	Year	Title
22617121	Ouandaogo et al.	2012	Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol	Entrez ID	Uniprot ID	Score
APP	351	P05067	0.56
GOLGA2	2801	Q08379	0.63
KLC1	3831	Q07866	0.63
PCM1	5108	Q15154	0.63
POLR2H	5437	P52434	0.63
PRKCI	5584	P41743	0.63
TCOF1	6949	Q13428	0.63
POC1A	25886	Q8NBT0	0.63
ZNF639	51193	Q9UID6	0.63
ZBTB2	57621	Q8N680	0.63
GOLPH3	64083	Q9H4A6	0.63
FAAP100	80233	Q0VG06	0.63
PARP10	84875	Q53GL7	0.63
PPP1CB	5500	P62140	0.72
TRIB1	10221	Q96RU8	0.72
APPBP2	10513	Q92624	0.72
KDM1A	23028	O60341	0.72
SETD2	29072	Q9BYW2	0.72
TBC1D24	57465	Q9ULP9	0.72
NLN	57486	Q9BYT8	0.72
RAB11FIP1	80223	Q6WKZ4	0.72
PPP1CA	5499	P62136	0.82
PPP1CC	5501	P36873	0.82
PPP1R13B	23368	Q96KQ4	0.82
FRMD6	122786	Q96NE9	0.82
YWHAG	7532	P61981	0.86
YAP1	10413	P46937	0.49
NINL	22981	Q9Y2I6	0.49
CEP152	22995	O94986	0.49
ANKRD28	23243	O15084	0.49
NIN	51199	Q8N4C6	0.49
AMOT	154796	Q4VCS5	0.49
LYN	4067	P07948	0.63
PSMD4	5710	P55036	0.63
SFRP4	6424	Q6FHJ7	0.63
YWHAE	7531	P62258	0.63
TIMM13	26517	Q9Y5L4	0.63
PDK1	5163	Q15118	0.72
RAB5C	5878	P51148	0.72
PARD6A	50855	Q9NPB6	0.72
PARD6B	84612	Q9BYG5	0.82
TP53BP2	7159	Q13625	0.83
PARD3	56288	Q8TEW0	0.83
YWHAH	7533	Q04917	0.87