| Gene Symbol | RPL35 |
| Entrez ID | 11224 |
| Uniprot ID | P42766 |
| Description | ribosomal protein L35 |
| Chromosomal Location | chr9: 124,857,880-124,861,981 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0000184 |
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins. |
TAS |
|
BP |
GO:0000463 |
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript. |
IBA |
|
BP |
GO:0006364 |
rRNA processing |
Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. |
TAS |
|
BP |
GO:0006412 |
translation |
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA. Translation ends with the release of a polypeptide chain from the ribosome. |
NAS |
|
BP |
GO:0006413 |
translational initiation |
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA. |
TAS |
|
BP |
GO:0006614 |
SRP-dependent cotranslational protein targeting to membrane |
The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane. |
TAS |
|
BP |
GO:0019083 |
viral transcription |
The process by which a viral genome, or part of a viral genome, is transcribed within the host cell. |
TAS |
|
CC |
GO:0005730 |
nucleolus |
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
TAS |
|
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
IDA |
|
CC |
GO:0005829 |
cytosol |
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
TAS |
|
CC |
GO:0016020 |
membrane |
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
IDA |
|
CC |
GO:0022625 |
cytosolic large ribosomal subunit |
The large subunit of a ribosome located in the cytosol. |
IDA |
|
MF |
GO:0003729 |
mRNA binding |
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns. |
TAS |
|
MF |
GO:0003735 |
structural constituent of ribosome |
The action of a molecule that contributes to the structural integrity of the ribosome. |
NAS |
|
MF |
GO:0044822 |
poly(A) RNA binding |
Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases. |
IDA |
| Domain ID | Description |
|---|---|
|
IPR001854 |
Ribosomal protein L29/L36 |
|
IPR018254 |
Ribosomal protein L29, conserved site |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
|
hsa03010 |
Ribosome |
KEGG |
|
WP477 |
Cytoplasmic Ribosomal Proteins |
WikiPathways |
| Tissue | Cell Type |
|---|---|
|
appendix |
glandular cells |
|
breast |
glandular cells |
|
breast |
myoepithelial cells |
|
cerebral cortex |
glial cells |
|
cerebral cortex |
neuronal cells |
|
colon |
glandular cells |
|
duodenum |
glandular cells |
|
endometrium |
glandular cells |
|
fallopian tube |
glandular cells |
|
hippocampus |
neuronal cells |
|
lymph node |
non-germinal center cells |
|
nasopharynx |
respiratory epithelial cells |
|
pancreas |
exocrine glandular cells |
|
placenta |
decidual cells |
|
placenta |
trophoblastic cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
skin |
epidermal cells |
|
stomach |
glandular cells |
|
thyroid gland |
glandular cells |
|
urinary bladder |
urothelial cells |
|
vagina |
squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
RPL13 |
6137 |
P26373 |
0.49 |
|
RPL15 |
6138 |
P61313 |
0.49 |
|
RPL35A |
6165 |
P18077 |
0.49 |
|
RPLP2 |
6181 |
P05387 |
0.49 |
|
RPS24 |
6229 |
P62847 |
0.49 |
|
RPS26 |
6231 |
P62854 |
0.49 |
|
TAF9 |
6880 |
Q16594 |
0.49 |
|
RNPS1 |
10921 |
Q15287 |
0.49 |
|
PABPC1 |
26986 |
P11940 |
0.49 |
|
MAX |
4149 |
P61244 |
0.56 |
|
RPL10A |
4736 |
P62906 |
0.56 |
|
RPL12 |
6136 |
P30050 |
0.56 |
|
RPL37A |
6168 |
P61513 |
0.56 |
|
RPS2 |
6187 |
P15880 |
0.56 |
|
RPS14 |
6208 |
P62263 |
0.56 |
|
RPS23 |
6228 |
P62266 |
0.56 |
|
RPL4 |
6124 |
P36578 |
0.58 |
|
RPL8 |
6132 |
P62917 |
0.58 |
|
RPL13A |
23521 |
P40429 |
0.58 |
|
RPL9; RPL9P7; RPL9P8; RPL9P9 |
6133 |
P32969 |
0.58 |
|
RPSA |
3921 |
P08865 |
0.59 |
|
RPL6 |
6128 |
Q02878 |
0.59 |
|
RPL7 |
6129 |
P18124 |
0.59 |
|
RPL7A |
6130 |
P62424 |
0.59 |
|
RPS7 |
6201 |
P62081 |
0.59 |
|
RPS8 |
6202 |
P62241 |
0.59 |
|
RPS19 |
6223 |
P39019 |
0.59 |
|
ADH4 |
127 |
P08319 |
0.63 |
|
HNRNPU |
3192 |
Q00839 |
0.63 |
|
PRPSAP1 |
5635 |
Q14558 |
0.63 |
|
CDC42BPB |
9578 |
Q9Y5S2 |
0.63 |
|
LAMC3 |
10319 |
Q9Y6N6 |
0.63 |
|
SND1 |
27044 |
Q7KZF4 |
0.63 |
|
SGSM3 |
27352 |
Q96HU1 |
0.63 |
|
TUBB2B |
347733 |
Q9BVA1 |
0.63 |
|
EIF3CL |
728689 |
B5ME19 |
0.63 |
|
RPL38 |
6169 |
P63173 |
0.65 |
|
RPS3A |
6189 |
P61247 |
0.65 |
|
RPS20 |
6224 |
P60866 |
0.65 |
|
RPL36 |
25873 |
Q9Y3U8 |
0.65 |
|
RPS12 |
6206 |
P25398 |
0.73 |
|
RPL17 |
6139 |
P18621 |
0.79 |
|
RPS11 |
6205 |
P62280 |
0.79 |
|
RPL10 |
6134 |
P27635 |
0.91 |
|
ATP1B3 |
483 |
P54709 |
0.49 |
|
CBFB |
865 |
Q13951 |
0.49 |
|
RPL18A |
6142 |
Q02543 |
0.49 |
|
RPL22 |
6146 |
P35268 |
0.49 |
|
RPL27 |
6155 |
P61353 |
0.49 |
|
RPL28 |
6158 |
P46779 |
0.49 |
|
RPN1 |
6184 |
P04843 |
0.49 |
|
RPS9 |
6203 |
P46781 |
0.49 |
|
RPS10 |
6204 |
P46783 |
0.49 |
|
RPS13 |
6207 |
P62277 |
0.49 |
|
RPS25 |
6230 |
P62851 |
0.49 |
|
UBA52 |
7311 |
P62987 |
0.49 |
|
RPL26L1 |
51121 |
Q9UNX3 |
0.49 |
|
RPL3 |
6122 |
P39023 |
0.56 |
|
RPL21 |
6144 |
P46778 |
0.56 |
|
RPL24 |
6152 |
P83731 |
0.56 |
|
RPL34 |
6164 |
P49207 |
0.56 |
|
RPS3 |
6188 |
P23396 |
0.56 |
|
RPS4X |
6191 |
P62701 |
0.56 |
|
RPS5 |
6193 |
P46782 |
0.56 |
|
RPS6 |
6194 |
P62753 |
0.56 |
|
RPS15A |
6210 |
P62244 |
0.56 |
|
RPS16 |
6217 |
P62249 |
0.56 |
|
RPS18 |
6222 |
P62269 |
0.56 |
|
RPL5 |
6125 |
P46777 |
0.58 |
|
RPL19 |
6143 |
P84098 |
0.58 |
|
RPLP0 |
6175 |
P05388 |
0.58 |
|
RPL23 |
9349 |
P62829 |
0.58 |
|
RPL18 |
6141 |
Q07020 |
0.59 |
|
RPL30 |
6156 |
P62888 |
0.59 |
|
RPL31 |
6160 |
P62899 |
0.59 |
|
RPL14 |
9045 |
P50914 |
0.59 |
|
RPL10L |
140801 |
Q96L21 |
0.59 |
|
ACTN2 |
88 |
P35609 |
0.63 |
|
PARP1 |
142 |
P09874 |
0.63 |
|
ADRBK1 |
156 |
P25098 |
0.63 |
|
CD81 |
975 |
P60033 |
0.63 |
|
CDK4 |
1019 |
P11802 |
0.63 |
|
CDK5 |
1020 |
Q00535 |
0.63 |
|
CDK9 |
1025 |
P50750 |
0.63 |
|
CDKN1A |
1026 |
P38936 |
0.63 |
|
MAPK14 |
1432 |
Q16539 |
0.63 |
|
CSK |
1445 |
P41240 |
0.63 |
|
CSNK1A1 |
1452 |
P48729 |
0.63 |
|
CSNK1E |
1454 |
P49674 |
0.63 |
|
CSNK2A2 |
1459 |
P19784 |
0.63 |
|
SFN |
2810 |
P31947 |
0.63 |
|
GSK3B |
2932 |
P49841 |
0.63 |
|
ICAM1 |
3383 |
P05362 |
0.63 |
|
ILK |
3611 |
Q13418 |
0.63 |
|
ITGA4 |
3676 |
P13612 |
0.63 |
|
JUN |
3725 |
P05412 |
0.63 |
|
LGALS3 |
3958 |
P17931 |
0.63 |
|
MAGEB2 |
4113 |
O15479 |
0.63 |
|
NEDD8 |
4738 |
Q15843 |
0.63 |
|
PAK1 |
5058 |
Q13153 |
0.63 |
|
PHKG2 |
5261 |
P15735 |
0.63 |
|
PRKACA |
5566 |
P17612 |
0.63 |
|
PRKACB |
5567 |
P22694 |
0.63 |
|
PRKCD |
5580 |
Q05655 |
0.63 |
|
EIF2AK2 |
5610 |
P19525 |
0.63 |
|
STK4 |
6789 |
Q13043 |
0.63 |
|
TMPO |
7112 |
P42166 |
0.63 |
|
TMPO |
7112 |
P42167 |
0.63 |
|
TRAF6 |
7189 |
Q9Y4K3 |
0.63 |
|
VHL |
7428 |
P40337 |
0.63 |
|
VRK1 |
7443 |
Q99986 |
0.63 |
|
YWHAZ |
7534 |
P63104 |
0.63 |
|
CNBP |
7555 |
P62633 |
0.63 |
|
CUL5 |
8065 |
Q93034 |
0.63 |
|
HIST1H3A |
8350 |
P68431 |
0.63 |
|
STK24 |
8428 |
Q9Y6E0 |
0.63 |
|
CUL4B |
8450 |
Q13620 |
0.63 |
|
CUL3 |
8452 |
Q13618 |
0.63 |
|
CUL1 |
8454 |
Q13616 |
0.63 |
|
CAMK1 |
8536 |
Q14012 |
0.63 |
|
EIF3D |
8664 |
O15371 |
0.63 |
|
KIAA0101 |
9768 |
Q15004 |
0.63 |
|
CUL7 |
9820 |
Q14999 |
0.63 |
|
PAN2 |
9924 |
Q504Q3 |
0.63 |
|
OXSR1 |
9943 |
O95747 |
0.63 |
|
G3BP1 |
10146 |
Q13283 |
0.63 |
|
STK25 |
10494 |
O00506 |
0.63 |
|
COPS5 |
10987 |
Q92905 |
0.63 |
|
CEP250 |
11190 |
Q9BV73 |
0.63 |
|
LARP1 |
23367 |
Q6PKG0 |
0.63 |
|
TARDBP |
23435 |
Q13148 |
0.63 |
|
AGO1 |
26523 |
Q9UL18 |
0.63 |
|
AGO2 |
27161 |
Q9UKV8 |
0.63 |
|
EEF2K |
29904 |
O00418 |
0.63 |
|
LUZP4 |
51213 |
Q9P127 |
0.63 |
|
STK26 |
51765 |
Q9P289 |
0.63 |
|
PINX1 |
54984 |
Q96BK5 |
0.63 |
|
LYAR |
55646 |
Q9NX58 |
0.63 |
|
RIOK2 |
55781 |
Q9BVS4 |
0.63 |
|
CAND1 |
55832 |
Q86VP6 |
0.63 |
|
PBK |
55872 |
Q96KB5 |
0.63 |
|
TXNDC16 |
57544 |
Q9P2K2 |
0.63 |
|
IGSF8 |
93185 |
Q969P0 |
0.63 |
|
TP53RK |
112858 |
Q96S44 |
0.63 |
|
RPL27A |
6157 |
P46776 |
0.65 |
|
RPL11 |
6135 |
P62913 |
0.68 |
|
RPS6KA1 |
6195 |
Q15418 |
0.70 |
|
EIF1B |
10289 |
O60739 |
0.70 |
|
ARRB2 |
409 |
P32121 |
0.72 |
|
FN1 |
2335 |
P02751 |
0.72 |
|
HDGF |
3068 |
P51858 |
0.72 |
|
MAP3K1 |
4214 |
Q13233 |
0.72 |
|
NPM1 |
4869 |
P06748 |
0.72 |
|
MAP3K14 |
9020 |
Q99558 |
0.72 |
|
AGO4 |
192670 |
Q9HCK5 |
0.72 |
|
CDK2 |
1017 |
P24941 |
0.73 |
|
PRKAA1 |
5562 |
Q13131 |
0.73 |
|
RPS27 |
6232 |
P42677 |
0.73 |
|
PSTPIP1 |
9051 |
O43586 |
0.76 |
|
RPL26 |
6154 |
P61254 |
0.79 |
|
VCAM1 |
7412 |
P19320 |
0.82 |
|
RPL23A |
6147 |
P62750 |
0.83 |