BP

GO:0006338

chromatin remodeling

Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.

IDA

BP

GO:0009117

nucleotide metabolic process

The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates).

NAS

BP

GO:0009191

ribonucleoside diphosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.

IDA

BP

GO:0019303

D-ribose catabolic process

The chemical reactions and pathways resulting in the breakdown of D-ribose (ribo-pentose).

IDA|NAS

BP

GO:0034656

nucleobase-containing small molecule catabolic process

The chemical reactions and pathways resulting in the breakdown of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.

TAS

BP

GO:1990966

ATP generation from poly-ADP-D-ribose

The process of generating ATP in the nucleus from poly-ADP-D-ribose. Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming.

IDA

CC

GO:0005622

intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

NAS

CC

GO:0005634

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

IDA

CC

GO:0005829

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

TAS

CC

GO:0070062

extracellular exosome

A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.

IDA

MF

GO:0000287

magnesium ion binding

Interacting selectively and non-covalently with magnesium (Mg) ions.

IDA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0016779

nucleotidyltransferase activity

Catalysis of the transfer of a nucleotidyl group to a reactant.

IDA

MF

GO:0019144

ADP-sugar diphosphatase activity

Catalysis of the reaction: ADP-sugar + H2O = AMP + sugar 1-phosphate.

IDA

MF

GO:0030515

snoRNA binding

Interacting selectively and non-covalently with small nucleolar RNA.

ISS

MF

GO:0042803

protein homodimerization activity

Interacting selectively and non-covalently with an identical protein to form a homodimer.

IDA

MF

GO:0044715

8-oxo-dGDP phosphatase activity

Catalysis of the reaction 8-oxo-dGDP + H2O = 8-oxo-dGMP + phosphate.

IDA

MF

GO:0047631

ADP-ribose diphosphatase activity

Catalysis of the reaction: ADP-ribose + H2O = AMP + D-ribose 5-phosphate.

EXP|IDA