| Gene Symbol | DUS4L |
| Entrez ID | 11062 |
| Uniprot ID | O95620 |
| Description | dihydrouridine synthase 4-like |
| Chromosomal Location | chr7: 107,563,484-107,578,464 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0002943 |
tRNA dihydrouridine synthesis |
The process whereby a uridine in a transfer RNA is converted to dihydrouridine. |
IEA |
|
BP |
GO:0055114 |
oxidation-reduction process |
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons. |
IEA |
|
CC |
GO:0005829 |
cytosol |
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
IBA |
|
MF |
GO:0017150 |
tRNA dihydrouridine synthase activity |
Catalysis of the reaction: tRNA-uracil + acceptor = tRNA-dihydrouridine + reduced acceptor. |
IBA |
|
MF |
GO:0050660 |
flavin adenine dinucleotide binding |
Interacting selectively and non-covalently with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2. |
IEA |
| Domain ID | Description |
|---|---|
|
IPR001269 |
tRNA-dihydrouridine synthase |
|
IPR013785 |
Aldolase-type TIM barrel |
|
IPR018517 |
tRNA-dihydrouridine synthase, conserved site |
| UMLS CUI | UMLS Term |
|---|---|
|
C0029408 |
Degenerative Polyarthritis |
| Tissue | Cell Type |
|---|---|
|
bronchus |
respiratory epithelial cells |
|
nasopharynx |
respiratory epithelial cells |
|
skin |
keratinocytes |
|
smooth muscle |
smooth muscle cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
17148555 |
Wood et al. |
2007 |
Molecular Abnormalities in Oocytes from Women with Polycystic Ovary Syndrome Revealed by Microarray Analysis |
|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
FANCA |
2175 |
O15360 |
0.63 |