| Gene Symbol | ILVBL |
| Entrez ID | 10994 |
| Uniprot ID | A1L0T0 |
| Description | ilvB (bacterial acetolactate synthase)-like |
| Chromosomal Location | chr19: 15,114,984-15,125,785 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
BP | GO:0008150 | biological_process |
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. | ND |
CC | GO:0016020 | membrane |
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. | IDA |
CC | GO:0016021 | integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. | IEA |
MF | GO:0000287 | magnesium ion binding |
Interacting selectively and non-covalently with magnesium (Mg) ions. | IEA |
MF | GO:0003674 | molecular_function |
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions. | ND |
MF | GO:0016740 | transferase activity |
Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. | IEA |
MF | GO:0030976 | thiamine pyrophosphate binding |
Interacting selectively and non-covalently with thiamine pyrophosphate, the diphosphoric ester of thiamine. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases. | IEA |
| Domain ID | Description |
|---|---|
IPR000399 | TPP-binding enzyme, conserved site |
IPR011766 | Thiamine pyrophosphate enzyme, C-terminal TPP-binding |
IPR012000 | Thiamine pyrophosphate enzyme, central domain |
IPR012001 | Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain |
IPR029035 | DHS-like NAD/FAD-binding domain |
IPR029061 | Thiamin diphosphate-binding fold |
| Tissue | Cell Type |
|---|---|
adrenal gland | glandular cells |
appendix | glandular cells |
appendix | lymphoid tissue |
bone marrow | hematopoietic cells |
breast | glandular cells |
breast | myoepithelial cells |
bronchus | respiratory epithelial cells |
caudate | glial cells |
caudate | neuronal cells |
cerebellum | cells in granular layer |
cerebellum | Purkinje cells |
cerebral cortex | endothelial cells |
cerebral cortex | neuronal cells |
cervix, uterine | glandular cells |
colon | endothelial cells |
colon | glandular cells |
duodenum | glandular cells |
endometrium | cells in endometrial stroma |
endometrium | glandular cells |
fallopian tube | glandular cells |
gallbladder | glandular cells |
kidney | cells in tubules |
lung | macrophages |
lung | pneumocytes |
lymph node | germinal center cells |
lymph node | non-germinal center cells |
nasopharynx | respiratory epithelial cells |
pancreas | exocrine glandular cells |
pancreas | islets of Langerhans |
placenta | trophoblastic cells |
prostate | glandular cells |
rectum | glandular cells |
salivary gland | glandular cells |
seminal vesicle | glandular cells |
skeletal muscle | myocytes |
skin | fibroblasts |
skin | keratinocytes |
skin | melanocytes |
skin | epidermal cells |
small intestine | glandular cells |
smooth muscle | smooth muscle cells |
soft tissue | chondrocytes |
soft tissue | fibroblasts |
soft tissue | adipocytes |
spleen | cells in red pulp |
spleen | cells in white pulp |
stomach | glandular cells |
testis | cells in seminiferous ducts |
testis | Leydig cells |
thyroid gland | glandular cells |
tonsil | germinal center cells |
tonsil | non-germinal center cells |
vagina | squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
22951915 | Haozi et al. | 2012 | Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
ATP1B1 | 481 | P05026 | 0.49 |
CYC1 | 1537 | P08574 | 0.49 |
NDUFS3 | 4722 | O75489 | 0.49 |
RAB1A | 5861 | P62820 | 0.49 |
SRSF1 | 6426 | Q07955 | 0.49 |
UQCRFS1 | 7386 | P47985 | 0.49 |
MTCH1 | 23787 | Q9NZJ7 | 0.49 |
HSD17B14 | 51171 | Q9BPX1 | 0.49 |
RAB14 | 51552 | P61106 | 0.49 |
XRCC6 | 2547 | P12956 | 0.63 |
ATXN1 | 6310 | P54253 | 0.63 |
TOM1 | 10043 | O60784 | 0.63 |
CEP76 | 79959 | Q8TAP6 | 0.63 |
ACAT1 | 38 | P24752 | 0.49 |
HNRNPC | 3183 | P07910 | 0.49 |
SLC25A3 | 5250 | Q00325 | 0.49 |
SDHB | 6390 | P21912 | 0.49 |
VDAC2 | 7417 | P45880 | 0.49 |
VDAC3 | 7419 | Q9Y277 | 0.49 |
PICALM | 8301 | Q13492 | 0.49 |
FLOT1 | 10211 | O75955 | 0.49 |
ATP5L | 10632 | O75964 | 0.49 |
RPGRIP1L | 23322 | Q68CZ1 | 0.49 |
TCTN3 | 26123 | Q6NUS6 | 0.49 |
UQCRQ | 27089 | O14949 | 0.49 |
ADRB2 | 154 | P07550 | 0.63 |
CLN3 | 1201 | Q13286 | 0.63 |
ECT2 | 1894 | Q9H8V3 | 0.63 |
NTRK1 | 4914 | P04629 | 0.63 |
SUMO2 | 6613 | P61956 | 0.63 |
STK4 | 6789 | Q13043 | 0.63 |
UBL4A | 8266 | P11441 | 0.63 |
CUL3 | 8452 | Q13618 | 0.63 |
MMS19 | 64210 | Q96T76 | 0.63 |
ILK | 3611 | Q13418 | 0.72 |
KIF11 | 3832 | P52732 | 0.72 |
MYC | 4609 | P01106 | 0.72 |
PPP6R2 | 9701 | O75170 | 0.72 |
PPP6R1 | 22870 | Q9UPN7 | 0.72 |
GBA2 | 57704 | Q9HCG7 | 0.72 |
SKA1 | 220134 | Q96BD8 | 0.72 |
EGFR | 1956 | P00533 | 0.82 |