| Gene Symbol | ILVBL |
| Entrez ID | 10994 |
| Uniprot ID | A1L0T0 |
| Description | ilvB (bacterial acetolactate synthase)-like |
| Chromosomal Location | chr19: 15,114,984-15,125,785 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0008150 |
biological_process |
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. |
ND |
|
CC |
GO:0016020 |
membrane |
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
IDA |
|
CC |
GO:0016021 |
integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IEA |
|
MF |
GO:0000287 |
magnesium ion binding |
Interacting selectively and non-covalently with magnesium (Mg) ions. |
IEA |
|
MF |
GO:0003674 |
molecular_function |
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions. |
ND |
|
MF |
GO:0016740 |
transferase activity |
Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. |
IEA |
|
MF |
GO:0030976 |
thiamine pyrophosphate binding |
Interacting selectively and non-covalently with thiamine pyrophosphate, the diphosphoric ester of thiamine. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases. |
IEA |
| Domain ID | Description |
|---|---|
|
IPR000399 |
TPP-binding enzyme, conserved site |
|
IPR011766 |
Thiamine pyrophosphate enzyme, C-terminal TPP-binding |
|
IPR012000 |
Thiamine pyrophosphate enzyme, central domain |
|
IPR012001 |
Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain |
|
IPR029035 |
DHS-like NAD/FAD-binding domain |
|
IPR029061 |
Thiamin diphosphate-binding fold |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
appendix |
glandular cells |
|
appendix |
lymphoid tissue |
|
bone marrow |
hematopoietic cells |
|
breast |
glandular cells |
|
breast |
myoepithelial cells |
|
bronchus |
respiratory epithelial cells |
|
caudate |
glial cells |
|
caudate |
neuronal cells |
|
cerebellum |
cells in granular layer |
|
cerebellum |
Purkinje cells |
|
cerebral cortex |
endothelial cells |
|
cerebral cortex |
neuronal cells |
|
cervix, uterine |
glandular cells |
|
colon |
endothelial cells |
|
colon |
glandular cells |
|
duodenum |
glandular cells |
|
endometrium |
cells in endometrial stroma |
|
endometrium |
glandular cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
kidney |
cells in tubules |
|
lung |
macrophages |
|
lung |
pneumocytes |
|
lymph node |
germinal center cells |
|
lymph node |
non-germinal center cells |
|
nasopharynx |
respiratory epithelial cells |
|
pancreas |
exocrine glandular cells |
|
pancreas |
islets of Langerhans |
|
placenta |
trophoblastic cells |
|
prostate |
glandular cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
seminal vesicle |
glandular cells |
|
skeletal muscle |
myocytes |
|
skin |
fibroblasts |
|
skin |
keratinocytes |
|
skin |
melanocytes |
|
skin |
epidermal cells |
|
small intestine |
glandular cells |
|
smooth muscle |
smooth muscle cells |
|
soft tissue |
chondrocytes |
|
soft tissue |
fibroblasts |
|
soft tissue |
adipocytes |
|
spleen |
cells in red pulp |
|
spleen |
cells in white pulp |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
testis |
Leydig cells |
|
thyroid gland |
glandular cells |
|
tonsil |
germinal center cells |
|
tonsil |
non-germinal center cells |
|
vagina |
squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
ATP1B1 |
481 |
P05026 |
0.49 |
|
CYC1 |
1537 |
P08574 |
0.49 |
|
NDUFS3 |
4722 |
O75489 |
0.49 |
|
RAB1A |
5861 |
P62820 |
0.49 |
|
SRSF1 |
6426 |
Q07955 |
0.49 |
|
UQCRFS1 |
7386 |
P47985 |
0.49 |
|
MTCH1 |
23787 |
Q9NZJ7 |
0.49 |
|
HSD17B14 |
51171 |
Q9BPX1 |
0.49 |
|
RAB14 |
51552 |
P61106 |
0.49 |
|
XRCC6 |
2547 |
P12956 |
0.63 |
|
ATXN1 |
6310 |
P54253 |
0.63 |
|
TOM1 |
10043 |
O60784 |
0.63 |
|
CEP76 |
79959 |
Q8TAP6 |
0.63 |
|
ACAT1 |
38 |
P24752 |
0.49 |
|
HNRNPC |
3183 |
P07910 |
0.49 |
|
SLC25A3 |
5250 |
Q00325 |
0.49 |
|
SDHB |
6390 |
P21912 |
0.49 |
|
VDAC2 |
7417 |
P45880 |
0.49 |
|
VDAC3 |
7419 |
Q9Y277 |
0.49 |
|
PICALM |
8301 |
Q13492 |
0.49 |
|
FLOT1 |
10211 |
O75955 |
0.49 |
|
ATP5L |
10632 |
O75964 |
0.49 |
|
RPGRIP1L |
23322 |
Q68CZ1 |
0.49 |
|
TCTN3 |
26123 |
Q6NUS6 |
0.49 |
|
UQCRQ |
27089 |
O14949 |
0.49 |
|
ADRB2 |
154 |
P07550 |
0.63 |
|
CLN3 |
1201 |
Q13286 |
0.63 |
|
ECT2 |
1894 |
Q9H8V3 |
0.63 |
|
NTRK1 |
4914 |
P04629 |
0.63 |
|
SUMO2 |
6613 |
P61956 |
0.63 |
|
STK4 |
6789 |
Q13043 |
0.63 |
|
UBL4A |
8266 |
P11441 |
0.63 |
|
CUL3 |
8452 |
Q13618 |
0.63 |
|
MMS19 |
64210 |
Q96T76 |
0.63 |
|
ILK |
3611 |
Q13418 |
0.72 |
|
KIF11 |
3832 |
P52732 |
0.72 |
|
MYC |
4609 |
P01106 |
0.72 |
|
PPP6R2 |
9701 |
O75170 |
0.72 |
|
PPP6R1 |
22870 |
Q9UPN7 |
0.72 |
|
GBA2 |
57704 |
Q9HCG7 |
0.72 |
|
SKA1 |
220134 |
Q96BD8 |
0.72 |
|
EGFR |
1956 |
P00533 |
0.82 |