Gene Symbol | STARD3 |
Entrez ID | 10948 |
Uniprot ID | Q14849 |
Description | StAR related lipid transfer domain containing 3 |
Chromosomal Location | chr17: 39,637,065-39,663,484 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006629 |
lipid metabolic process |
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids. |
TAS |
BP |
GO:0006701 |
progesterone biosynthetic process |
The chemical reactions and pathways resulting in the formation of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants. |
IEA |
BP |
GO:0006839 |
mitochondrial transport |
Transport of substances into, out of or within a mitochondrion. |
TAS |
BP |
GO:0006869 |
lipid transport |
The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. |
IEA |
BP |
GO:0008202 |
steroid metabolic process |
The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. |
TAS |
BP |
GO:0008203 |
cholesterol metabolic process |
The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues. |
TAS |
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
TAS |
CC |
GO:0005739 |
mitochondrion |
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
IBA |
CC |
GO:0005765 |
lysosomal membrane |
The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm. |
IDA |
CC |
GO:0016021 |
integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IEA |
CC |
GO:0031902 |
late endosome membrane |
The lipid bilayer surrounding a late endosome. |
IEA |
MF |
GO:0015485 |
cholesterol binding |
Interacting selectively and non-covalently with cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. |
IDA |
Domain ID | Description |
---|---|
IPR000799 |
Steroidogenic acute regulatory protein-like |
IPR002913 |
START domain |
IPR019498 |
MENTAL domain |
IPR023393 |
START-like domain |
IPR029867 |
StAR-related lipid transfer protein 3 |
UMLS CUI | UMLS Term |
---|---|
C0033578 |
Prostatic Neoplasms |
Tissue | Cell Type |
---|---|
adrenal gland |
glandular cells |
appendix |
glandular cells |
bone marrow |
hematopoietic cells |
bronchus |
respiratory epithelial cells |
caudate |
neuronal cells |
cerebellum |
Purkinje cells |
cerebral cortex |
neuronal cells |
duodenum |
glandular cells |
endometrium |
glandular cells |
epididymis |
glandular cells |
fallopian tube |
glandular cells |
gallbladder |
glandular cells |
heart muscle |
myocytes |
hippocampus |
neuronal cells |
kidney |
cells in tubules |
liver |
bile duct cells |
lymph node |
germinal center cells |
pancreas |
exocrine glandular cells |
parathyroid gland |
glandular cells |
placenta |
trophoblastic cells |
prostate |
glandular cells |
seminal vesicle |
glandular cells |
skeletal muscle |
myocytes |
small intestine |
glandular cells |
spleen |
cells in white pulp |
stomach |
glandular cells |
testis |
cells in seminiferous ducts |
tonsil |
germinal center cells |
tonsil |
non-germinal center cells |
urinary bladder |
urothelial cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
GOPC |
57120 |
Q9HD26 |
0.63 |
VAPA |
9218 |
Q9P0L0 |
0.74 |
CREB3 |
10488 |
O43889 |
0.63 |
SDF4 |
51150 |
Q9BRK5 |
0.63 |
ERGIC3 |
51614 |
Q9Y282 |
0.63 |
SPACA1 |
81833 |
Q9HBV2 |
0.63 |
HEPACAM2 |
253012 |
A8MVW5 |
0.63 |
VAPB |
9217 |
O95292 |
0.83 |