Protein Description

Gene Symbol STARD3
Entrez ID 10948
Uniprot ID Q14849
Description StAR related lipid transfer domain containing 3
Chromosomal Location chr17: 39,637,065-39,663,484
Ontology GO ID GO Term Definition Evidence

BP

GO:0006629

lipid metabolic process

The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.

TAS

BP

GO:0006701

progesterone biosynthetic process

The chemical reactions and pathways resulting in the formation of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.

IEA

BP

GO:0006839

mitochondrial transport

Transport of substances into, out of or within a mitochondrion.

TAS

BP

GO:0006869

lipid transport

The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.

IEA

BP

GO:0008202

steroid metabolic process

The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.

TAS

BP

GO:0008203

cholesterol metabolic process

The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues.

TAS

CC

GO:0005737

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

TAS

CC

GO:0005739

mitochondrion

A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

IBA

CC

GO:0005765

lysosomal membrane

The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.

IDA

CC

GO:0016021

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

IEA

CC

GO:0031902

late endosome membrane

The lipid bilayer surrounding a late endosome.

IEA

MF

GO:0015485

cholesterol binding

Interacting selectively and non-covalently with cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.

IDA

Domain ID Description

IPR000799

Steroidogenic acute regulatory protein-like

IPR002913

START domain

IPR019498

MENTAL domain

IPR023393

START-like domain

IPR029867

StAR-related lipid transfer protein 3

No pathways found.

UMLS CUI UMLS Term

C0033578

Prostatic Neoplasms

Tissue Cell Type

adrenal gland

glandular cells

appendix

glandular cells

bone marrow

hematopoietic cells

bronchus

respiratory epithelial cells

caudate

neuronal cells

cerebellum

Purkinje cells

cerebral cortex

neuronal cells

duodenum

glandular cells

endometrium

glandular cells

epididymis

glandular cells

fallopian tube

glandular cells

gallbladder

glandular cells

heart muscle

myocytes

hippocampus

neuronal cells

kidney

cells in tubules

liver

bile duct cells

lymph node

germinal center cells

pancreas

exocrine glandular cells

parathyroid gland

glandular cells

placenta

trophoblastic cells

prostate

glandular cells

seminal vesicle

glandular cells

skeletal muscle

myocytes

small intestine

glandular cells

spleen

cells in white pulp

stomach

glandular cells

testis

cells in seminiferous ducts

tonsil

germinal center cells

tonsil

non-germinal center cells

urinary bladder

urothelial cells

No databases found.

Pubmed ID Author Year Title

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

GOPC

57120

Q9HD26

0.63

VAPA

9218

Q9P0L0

0.74

CREB3

10488

O43889

0.63

SDF4

51150

Q9BRK5

0.63

ERGIC3

51614

Q9Y282

0.63

SPACA1

81833

Q9HBV2

0.63

HEPACAM2

253012

A8MVW5

0.63

VAPB

9217

O95292

0.83