Gene Symbol | NMU |
Entrez ID | 10874 |
Uniprot ID | P48645 |
Description | neuromedin U |
Chromosomal Location | chr4: 55,595,229-55,636,698 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0001696 |
gastric acid secretion |
The regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. |
IEA |
BP |
GO:0006940 |
regulation of smooth muscle contraction |
Any process that modulates the frequency, rate or extent of smooth muscle contraction. |
TAS |
BP |
GO:0007165 |
signal transduction |
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. |
TAS |
BP |
GO:0007186 |
G-protein coupled receptor signaling pathway |
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576). |
TAS |
BP |
GO:0007218 |
neuropeptide signaling pathway |
The series of molecular signals generated as a consequence of a peptide neurotransmitter binding to a cell surface receptor. |
IEA |
BP |
GO:0007586 |
digestion |
The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. |
TAS |
BP |
GO:0009648 |
photoperiodism |
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a period of light or dark of a given length, measured relative to a particular duration known as the 'critical day length'. The critical day length varies between species. |
IEA |
BP |
GO:0019233 |
sensory perception of pain |
The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process. |
IEA |
BP |
GO:0042755 |
eating behavior |
The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue. |
IEA |
BP |
GO:0045987 |
positive regulation of smooth muscle contraction |
Any process that activates or increases the frequency, rate or extent of smooth muscle contraction. |
IEA |
BP |
GO:0046887 |
positive regulation of hormone secretion |
Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell. |
IEA |
BP |
GO:0050806 |
positive regulation of synaptic transmission |
Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. |
IEA |
CC |
GO:0005576 |
extracellular region |
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. |
TAS |
CC |
GO:0043195 |
terminal bouton |
Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it. |
IEA |
MF |
GO:0005102 |
receptor binding |
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. |
TAS |
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
MF |
GO:0042922 |
neuromedin U receptor binding |
Interacting selectively and non-covalently with one or more specific sites on a neuromedin U receptor. |
IEA |
Domain ID | Description |
---|---|
IPR008200 |
Neuromedin U, C-terminal |
IPR018070 |
Neuromedin U, amidation site |
UMLS CUI | UMLS Term |
---|---|
C0017661 |
Iga Glomerulonephritis |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
23824412 |
Piltonen et al. |
2013 |
Mesenchymal Stem/Progenitors and Other Endometrial Cell Types From Women With Polycystic Ovary Syndrome (PCOS) Display Inflammatory and Oncogenic Potential |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
TNS2 |
23371 |
Q63HR2 |
0.63 |
NOTCH2NL |
388677 |
Q7Z3S9 |
0.63 |
SNTA1 |
6640 |
Q13424 |
0.49 |
HLA-DPA1 |
3113 |
P20036 |
0.63 |
KRTAP5-9 |
3846 |
P26371 |
0.63 |
B3GALNT1 |
8706 |
O75752 |
0.63 |
IL20RB |
53833 |
Q6UXL0 |
0.63 |
GINM1 |
116254 |
Q9NU53 |
0.63 |
NMUR1 |
10316 |
Q9HB89 |
0.93 |
NMUR2 |
56923 |
Q9GZQ4 |
0.93 |