Gene Symbol | CDH15 |
Entrez ID | 1013 |
Uniprot ID | P55291 |
Description | cadherin 15, type 1, M-cadherin (myotubule) |
Chromosomal Location | chr16: 89,171,767-89,195,492 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0007155 |
cell adhesion |
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. |
TAS |
BP |
GO:0007156 |
homophilic cell adhesion via plasma membrane adhesion molecules |
The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell. |
IEA |
BP |
GO:0034332 |
adherens junction organization |
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an adherens junction. An adherens junction is a cell junction at which the cytoplasmic face of the plasma membrane is attached to actin filaments. |
TAS |
BP |
GO:0051149 |
positive regulation of muscle cell differentiation |
Any process that activates or increases the frequency, rate or extent of muscle cell differentiation. |
TAS |
CC |
GO:0005886 |
plasma membrane |
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
TAS |
CC |
GO:0005901 |
caveola |
A membrane raft that forms small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane. Examples include flask-shaped invaginations of the plasma membrane in adipocytes associated with caveolin proteins, and minute pits or incuppings of the cell membrane formed during pinocytosis. Caveolae may be pinched off to form free vesicles within the cytoplasm. |
IEA |
CC |
GO:0016021 |
integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IEA |
CC |
GO:0031594 |
neuromuscular junction |
The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential. |
IEA |
CC |
GO:0070062 |
extracellular exosome |
A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. |
IDA |
MF |
GO:0005509 |
calcium ion binding |
Interacting selectively and non-covalently with calcium ions (Ca2+). |
IEA |
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
Domain ID | Description |
---|---|
IPR000233 |
Cadherin, cytoplasmic domain |
IPR002126 |
Cadherin |
IPR015919 |
Cadherin-like |
IPR020894 |
Cadherin conserved site |
IPR027397 |
Catenin binding domain |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa04514 |
Cell adhesion molecules (CAMs) |
KEGG |
Tissue | Cell Type |
---|---|
skeletal muscle |
myocytes |
smooth muscle |
smooth muscle cells |
Database Name |
---|
DisGeNET |
Pubmed ID | Author | Year | Title |
---|---|---|---|
21411543 |
Savaris et al. |
2011 |
Progesterone Resistance in PCOS Endometrium: A Microarray Analysis in Clomiphene Citrate-Treated and Artificial Menstrual Cycles |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
SGTA |
6449 |
O43765 |
0.63 |
CDH7 |
1005 |
Q9ULB5 |
0.52 |
CDH9 |
1007 |
Q9ULB4 |
0.52 |
CTNNA1 |
1495 |
P35221 |
0.52 |
CTNNB1 |
1499 |
P35222 |
0.52 |
JUP |
3728 |
P14923 |
0.52 |
CDON |
50937 |
Q4KMG0 |
0.65 |
BOC |
91653 |
Q9BWV1 |
0.65 |
GNA12 |
2768 |
Q03113 |
0.78 |
ARVCF |
421 |
O00192 |
0.86 |