| Gene Symbol | NUP50 |
| Entrez ID | 10762 |
| Uniprot ID | Q9UKX7 |
| Description | nucleoporin 50kDa |
| Chromosomal Location | chr22: 45,163,841-45,188,015 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0006406 |
mRNA export from nucleus |
The directed movement of mRNA from the nucleus to the cytoplasm. |
TAS |
|
BP |
GO:0006409 |
tRNA export from nucleus |
The directed movement of tRNA from the nucleus to the cytoplasm. |
TAS |
|
BP |
GO:0006606 |
protein import into nucleus |
The directed movement of a protein from the cytoplasm to the nucleus. |
IBA |
|
BP |
GO:0007077 |
mitotic nuclear envelope disassembly |
The cell cycle process in which the controlled breakdown of the nuclear envelope during mitotic cell division occurs. |
TAS |
|
BP |
GO:0010827 |
regulation of glucose transport |
Any process that modulates the frequency, rate or extent of glucose transport. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
TAS |
|
BP |
GO:0016032 |
viral process |
A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle. |
TAS |
|
BP |
GO:0016925 |
protein sumoylation |
The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxyl terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein. |
TAS |
|
BP |
GO:0019083 |
viral transcription |
The process by which a viral genome, or part of a viral genome, is transcribed within the host cell. |
TAS |
|
BP |
GO:0031047 |
gene silencing by RNA |
Any process in which RNA molecules inactivate expression of target genes. |
TAS |
|
BP |
GO:0075733 |
intracellular transport of virus |
The directed movement of a virus, or part of a virus, within the host cell. |
TAS |
|
BP |
GO:1900034 |
regulation of cellular response to heat |
Any process that modulates the frequency, rate or extent of cellular response to heat. |
TAS |
|
CC |
GO:0005643 |
nuclear pore |
Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined. |
IEA |
|
CC |
GO:0005654 |
nucleoplasm |
That part of the nuclear content other than the chromosomes or the nucleolus. |
IDA|TAS |
|
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
IDA |
|
CC |
GO:0031965 |
nuclear membrane |
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space. |
IDA |
|
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
|
MF |
GO:0008536 |
Ran GTPase binding |
Interacting selectively and non-covalently with Ran, a conserved Ras-like GTP-binding protein, implicated in nucleocytoplasmic transport, cell cycle progression, spindle assembly, nuclear organization and nuclear envelope (NE) assembly. |
IBA |
| Domain ID | Description |
|---|---|
|
IPR000156 |
Ran binding domain |
|
IPR011993 |
PH domain-like |
|
IPR015007 |
Nuclear pore complex, NUP2/50/61 |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
|
hsa03013 |
RNA transport |
KEGG |
| Tissue | Cell Type |
|---|---|
|
appendix |
glandular cells |
|
appendix |
lymphoid tissue |
|
breast |
glandular cells |
|
bronchus |
respiratory epithelial cells |
|
caudate |
neuronal cells |
|
cerebellum |
Purkinje cells |
|
cerebral cortex |
neuronal cells |
|
cervix, uterine |
glandular cells |
|
cervix, uterine |
squamous epithelial cells |
|
colon |
glandular cells |
|
duodenum |
glandular cells |
|
endometrium |
glandular cells |
|
epididymis |
glandular cells |
|
esophagus |
squamous epithelial cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
hippocampus |
neuronal cells |
|
kidney |
cells in glomeruli |
|
kidney |
cells in tubules |
|
lung |
macrophages |
|
lung |
pneumocytes |
|
lymph node |
non-germinal center cells |
|
nasopharynx |
respiratory epithelial cells |
|
oral mucosa |
squamous epithelial cells |
|
ovary |
follicle cells |
|
pancreas |
exocrine glandular cells |
|
pancreas |
islets of Langerhans |
|
placenta |
decidual cells |
|
placenta |
trophoblastic cells |
|
prostate |
glandular cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
seminal vesicle |
glandular cells |
|
skin |
fibroblasts |
|
skin |
keratinocytes |
|
skin |
Langerhans |
|
skin |
melanocytes |
|
skin |
epidermal cells |
|
small intestine |
glandular cells |
|
soft tissue |
fibroblasts |
|
spleen |
cells in red pulp |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
testis |
Leydig cells |
|
tonsil |
germinal center cells |
|
tonsil |
non-germinal center cells |
|
tonsil |
squamous epithelial cells |
|
urinary bladder |
urothelial cells |
|
vagina |
squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
FLNB |
2317 |
O75369 |
0.49 |
|
GMFB |
2764 |
P60983 |
0.49 |
|
IMPDH2 |
3615 |
P12268 |
0.49 |
|
NARS |
4677 |
O43776 |
0.49 |
|
PFDN4 |
5203 |
Q9NQP4 |
0.49 |
|
PLEC |
5339 |
Q15149 |
0.49 |
|
PRKAA1 |
5562 |
Q13131 |
0.49 |
|
RANBP1 |
5902 |
P43487 |
0.49 |
|
STXBP1 |
6812 |
P61764 |
0.49 |
|
PSME3 |
10197 |
P61289 |
0.49 |
|
PAIP1 |
10605 |
Q9H074 |
0.49 |
|
HSPBP1 |
23640 |
Q9NZL4 |
0.49 |
|
TOR1AIP1 |
26092 |
Q5JTV8 |
0.49 |
|
CCDC22 |
28952 |
O60826 |
0.49 |
|
SBDS |
51119 |
Q9Y3A5 |
0.49 |
|
UBAP2 |
55833 |
Q5T6F2 |
0.49 |
|
RAN |
5901 |
P62826 |
0.55 |
|
XPO1 |
7514 |
O14980 |
0.55 |
|
APP |
351 |
P05067 |
0.56 |
|
ACACA |
31 |
Q13085 |
0.63 |
|
EPB41L1 |
2036 |
Q9H4G0 |
0.63 |
|
KIF5B |
3799 |
P33176 |
0.63 |
|
KIFC1 |
3833 |
Q9BW19 |
0.63 |
|
RANBP2 |
5903 |
P49792 |
0.63 |
|
SMARCC2 |
6601 |
Q8TAQ2 |
0.63 |
|
SMARCD1 |
6602 |
Q96GM5 |
0.63 |
|
SMARCD2 |
6603 |
Q92925 |
0.63 |
|
SMARCD3 |
6604 |
Q6STE5 |
0.63 |
|
TAF4 |
6874 |
O00268 |
0.63 |
|
TP53BP1 |
7158 |
Q12888 |
0.63 |
|
SPOP |
8405 |
O43791 |
0.63 |
|
RNGTT |
8732 |
O60942 |
0.63 |
|
TSC22D1 |
8848 |
Q15714 |
0.63 |
|
BCL7B |
9275 |
Q9BQE9 |
0.63 |
|
TTI1 |
9675 |
O43156 |
0.63 |
|
SETD1A |
9739 |
O15047 |
0.63 |
|
WDHD1 |
11169 |
O75717 |
0.63 |
|
FBXO28 |
23219 |
Q9NVF7 |
0.63 |
|
KIAA1033 |
23325 |
Q2M389 |
0.63 |
|
BRD7 |
29117 |
Q9NPI1 |
0.63 |
|
CXXC1 |
30827 |
Q9P0U4 |
0.63 |
|
PBRM1 |
55193 |
Q86U86 |
0.63 |
|
MRGBP |
55257 |
Q9NV56 |
0.63 |
|
PHF10 |
55274 |
Q8WUB8 |
0.63 |
|
KLHL7 |
55975 |
Q8IXQ5 |
0.63 |
|
KIF18B |
146909 |
Q86Y91 |
0.63 |
|
CDCA2 |
157313 |
Q69YH5 |
0.63 |
|
ARID2 |
196528 |
Q68CP9 |
0.63 |
|
BOD1L1 |
259282 |
Q8NFC6 |
0.63 |
|
CDKN1B |
1027 |
P46527 |
0.78 |
|
KPNA6 |
23633 |
O60684 |
0.82 |
|
NUP153 |
9972 |
P49790 |
0.87 |
|
KPNB1 |
3837 |
Q14974 |
0.89 |
|
KPNA2 |
3838 |
P52292 |
0.94 |
|
AP2B1 |
163 |
P63010 |
0.49 |
|
ASNS |
440 |
P08243 |
0.49 |
|
EIF4G1 |
1981 |
Q04637 |
0.49 |
|
GARS |
2617 |
P41250 |
0.49 |
|
LDHB |
3945 |
P07195 |
0.49 |
|
PFDN2 |
5202 |
Q9UHV9 |
0.49 |
|
DYNLT1 |
6993 |
P63172 |
0.49 |
|
KHSRP |
8570 |
Q92945 |
0.49 |
|
NUP160 |
23279 |
Q12769 |
0.49 |
|
CDV3 |
55573 |
Q9UKY7 |
0.49 |
|
NUP133 |
55746 |
Q8WUM0 |
0.49 |
|
NUP85 |
79902 |
Q9BW27 |
0.49 |
|
B9D2 |
80776 |
Q9BPU9 |
0.49 |
|
NUP35 |
129401 |
Q8NFH5 |
0.49 |
|
TCTE1 |
202500 |
Q5JU00 |
0.49 |
|
NUP43 |
348995 |
Q8NFH3 |
0.49 |
|
LMNA |
4000 |
P02545 |
0.59 |
|
IFI16 |
3428 |
Q16666 |
0.63 |
|
KPNA4 |
3839 |
O00629 |
0.63 |
|
NPM1 |
4869 |
P06748 |
0.63 |
|
NTRK1 |
4914 |
P04629 |
0.63 |
|
PPP1CC |
5501 |
P36873 |
0.63 |
|
PPP1R3A |
5506 |
Q16821 |
0.63 |
|
IKBKAP |
8518 |
O95163 |
0.63 |
|
SART3 |
9733 |
Q15020 |
0.63 |
|
KIAA0101 |
9768 |
Q15004 |
0.63 |
|
PTBP3 |
9991 |
O95758 |
0.63 |
|
FBXW11 |
23291 |
Q9UKB1 |
0.63 |
|
LRRK2 |
120892 |
Q5S007 |
0.63 |
|
SRPK2 |
6733 |
P78362 |
0.70 |
|
HDAC6 |
10013 |
Q9UBN7 |
0.72 |
|
CUL3 |
8452 |
Q13618 |
0.73 |
|
IPO13 |
9670 |
O94829 |
0.75 |
|
SLX4 |
84464 |
Q8IY92 |
0.76 |
|
KPNA3 |
3840 |
O00505 |
0.82 |
|
KPNA5 |
3841 |
O15131 |
0.82 |
|
NUP107 |
57122 |
P57740 |
0.82 |
|
KPNA1 |
3836 |
P52294 |
0.87 |