BP

GO:0000902

cell morphogenesis

The developmental process in which the size or shape of a cell is generated and organized.

ISS

BP

GO:0001946

lymphangiogenesis

Lymph vessel formation when new vessels emerge from the proliferation of pre-existing vessels.

ISS

BP

GO:0006693

prostaglandin metabolic process

The chemical reactions and pathways involving prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities.

IEA

BP

GO:0007165

signal transduction

The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.

IEA

BP

GO:0008283

cell proliferation

The multiplication or reproduction of cells, resulting in the expansion of a cell population.

IEA

BP

GO:0008360

regulation of cell shape

Any process that modulates the surface configuration of a cell.

IEA

BP

GO:0016337

single organismal cell-cell adhesion

The attachment of one cell to another cell via adhesion molecules, where both cells are part of the same organism.

IEA

BP

GO:0030168

platelet activation

A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.

TAS

BP

GO:0030324

lung development

The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.

ISS

BP

GO:0048286

lung alveolus development

The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways.

IEA

BP

GO:0048870

cell motility

Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.

IBA

BP

GO:0051272

positive regulation of cellular component movement

Any process that activates or increases the frequency, rate or extent of the movement of a cellular component.

ISS

BP

GO:2000045

regulation of G1/S transition of mitotic cell cycle

Any cell cycle regulatory process that controls the commitment of a cell from G1 to S phase of the mitotic cell cycle.

IEA

CC

GO:0001726

ruffle

Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork.

ISS

CC

GO:0005886

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

ISS|TAS

CC

GO:0005887

integral component of plasma membrane

The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

TAS

CC

GO:0009897

external side of plasma membrane

The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.

IEA

CC

GO:0030027

lamellipodium

A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.

ISS

CC

GO:0030175

filopodium

Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft.

ISS

CC

GO:0031258

lamellipodium membrane

The portion of the plasma membrane surrounding a lamellipodium.

IEA

CC

GO:0031527

filopodium membrane

The portion of the plasma membrane surrounding a filopodium.

IEA

CC

GO:0031528

microvillus membrane

The portion of the plasma membrane surrounding a microvillus.

IEA

CC

GO:0032587

ruffle membrane

The portion of the plasma membrane surrounding a ruffle.

IEA