| Gene Symbol | CHERP |
| Entrez ID | 10523 |
| Uniprot ID | Q8IWX8 |
| Description | calcium homeostasis endoplasmic reticulum protein |
| Chromosomal Location | chr19: 16,517,889-16,542,530 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0006396 |
RNA processing |
Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. |
IEA |
|
BP |
GO:0006874 |
cellular calcium ion homeostasis |
Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell. |
IDA |
|
BP |
GO:0007399 |
nervous system development |
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state. |
TAS |
|
BP |
GO:0008285 |
negative regulation of cell proliferation |
Any process that stops, prevents or reduces the rate or extent of cell proliferation. |
IDA |
|
BP |
GO:0051209 |
release of sequestered calcium ion into cytosol |
The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the cytosolic compartment. |
IMP |
|
BP |
GO:0051533 |
positive regulation of NFAT protein import into nucleus |
Any process that activates or increases the frequency, rate or extent of the movement of an NFAT protein from the cytoplasm to the nucleus. |
IMP |
|
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
IDA |
|
CC |
GO:0016020 |
membrane |
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
IDA |
|
CC |
GO:0033017 |
sarcoplasmic reticulum membrane |
The lipid bilayer surrounding the sarcoplasmic reticulum. |
ISS |
|
CC |
GO:0048471 |
perinuclear region of cytoplasm |
Cytoplasm situated near, or occurring around, the nucleus. |
IDA |
|
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
|
MF |
GO:0044325 |
ion channel binding |
Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient. |
IPI |
|
MF |
GO:0044822 |
poly(A) RNA binding |
Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases. |
IDA |
| Domain ID | Description |
|---|---|
|
IPR000061 |
SWAP/Surp |
|
IPR000467 |
G-patch domain |
|
IPR006569 |
CID domain |
|
IPR006903 |
RNA polymerase II-binding domain |
|
IPR008942 |
ENTH/VHS |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
|
hsa03040 |
Spliceosome |
KEGG |
| Tissue | Cell Type |
|---|---|
|
appendix |
glandular cells |
|
bone marrow |
hematopoietic cells |
|
breast |
glandular cells |
|
bronchus |
respiratory epithelial cells |
|
caudate |
glial cells |
|
caudate |
neuronal cells |
|
cerebellum |
cells in molecular layer |
|
cerebellum |
Purkinje cells |
|
cerebral cortex |
glial cells |
|
cerebral cortex |
neuronal cells |
|
cervix, uterine |
glandular cells |
|
cervix, uterine |
squamous epithelial cells |
|
colon |
glandular cells |
|
colon |
peripheral nerve/ganglion |
|
duodenum |
glandular cells |
|
endometrium |
glandular cells |
|
epididymis |
glandular cells |
|
esophagus |
squamous epithelial cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
hippocampus |
neuronal cells |
|
kidney |
cells in glomeruli |
|
kidney |
cells in tubules |
|
lymph node |
germinal center cells |
|
lymph node |
non-germinal center cells |
|
nasopharynx |
respiratory epithelial cells |
|
oral mucosa |
squamous epithelial cells |
|
ovary |
follicle cells |
|
pancreas |
exocrine glandular cells |
|
placenta |
decidual cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
seminal vesicle |
glandular cells |
|
skin |
epidermal cells |
|
small intestine |
glandular cells |
|
smooth muscle |
smooth muscle cells |
|
soft tissue |
fibroblasts |
|
spleen |
cells in red pulp |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
testis |
Leydig cells |
|
thyroid gland |
glandular cells |
|
tonsil |
non-germinal center cells |
|
tonsil |
squamous epithelial cells |
|
urinary bladder |
urothelial cells |
|
vagina |
squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
12734205 |
Wood et al. |
2003 |
The Molecular Phenotype of Polycystic Ovary Syndrome (PCOS) Theca Cells and New Candidate PCOS Genes Defined by Microarray Analysis |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
PDE6A |
5145 |
P16499 |
0.49 |
|
PFAS |
5198 |
O15067 |
0.49 |
|
U2SURP |
23350 |
O15042 |
0.49 |
|
ZNF827 |
152485 |
Q17R98 |
0.49 |
|
EWSR1 |
2130 |
Q01844 |
0.63 |
|
HNRNPH3 |
3189 |
P31942 |
0.63 |
|
RPL31 |
6160 |
P62899 |
0.63 |
|
SART1 |
9092 |
O43290 |
0.63 |
|
RBM39 |
9584 |
Q14498 |
0.63 |
|
RBM7 |
10179 |
Q9Y580 |
0.63 |
|
RACK1 |
10399 |
P63244 |
0.63 |
|
RNPS1 |
10921 |
Q15287 |
0.63 |
|
ARGLU1 |
55082 |
Q9NWB6 |
0.63 |
|
AGGF1 |
55109 |
Q8N302 |
0.63 |
|
RBM23 |
55147 |
Q86U06 |
0.63 |
|
CCAR1 |
55749 |
Q8IX12 |
0.63 |
|
SNIP1 |
79753 |
Q8TAD8 |
0.63 |
|
PRPF38A |
84950 |
Q8NAV1 |
0.63 |
|
PPIL4 |
85313 |
Q8WUA2 |
0.63 |
|
LRRK2 |
120892 |
Q5S007 |
0.63 |
|
TTC14 |
151613 |
Q96N46 |
0.63 |
|
SRPK2 |
6733 |
P78362 |
0.70 |
|
DHX8 |
1659 |
Q14562 |
0.76 |
|
SNRNP27 |
11017 |
Q8WVK2 |
0.76 |
|
LUC7L |
55692 |
Q9NQ29 |
0.76 |
|
FRA10AC1 |
118924 |
Q70Z53 |
0.76 |
|
BMI1 |
648 |
P35226 |
0.63 |
|
CDC5L |
988 |
Q99459 |
0.63 |
|
DHX15 |
1665 |
O43143 |
0.63 |
|
RPSA |
3921 |
P08865 |
0.63 |
|
NTRK1 |
4914 |
P04629 |
0.63 |
|
RPA1 |
6117 |
P27694 |
0.63 |
|
RPA2 |
6118 |
P15927 |
0.63 |
|
RPA3 |
6119 |
P35244 |
0.63 |
|
RPS2 |
6187 |
P15880 |
0.63 |
|
RPS8 |
6202 |
P62241 |
0.63 |
|
SUMO3 |
6612 |
P55854 |
0.63 |
|
SNRNP70 |
6625 |
P08621 |
0.63 |
|
U2AF1 |
7307 |
Q01081 |
0.63 |
|
WHSC1 |
7468 |
O96028 |
0.63 |
|
ZRSR2 |
8233 |
Q15696 |
0.63 |
|
HIST1H3A |
8350 |
P68431 |
0.63 |
|
SF3B4 |
10262 |
Q15427 |
0.63 |
|
SNW1 |
22938 |
Q13573 |
0.63 |
|
OBSL1 |
23363 |
O75147 |
0.63 |
|
DDX41 |
51428 |
Q9UJV9 |
0.63 |
|
SIRT7 |
51547 |
Q9NRC8 |
0.63 |
|
PRPF40A |
55660 |
O75400 |
0.63 |
|
WDFY2 |
115825 |
Q96P53 |
0.63 |
|
SCARNA22 |
677770 |
N/A |
0.63 |
|
APBB1 |
322 |
O00213 |
0.68 |
|
WBP4 |
11193 |
O75554 |
0.68 |
|
SRPK1 |
6732 |
Q96SB4 |
0.70 |
|
CD44 |
960 |
P16070 |
0.72 |
|
MYO1C |
4641 |
O00159 |
0.72 |
|
XRCC3 |
7517 |
O43542 |
0.72 |
|
TRIM26 |
7726 |
Q12899 |
0.72 |
|
EMC2 |
9694 |
Q15006 |
0.72 |
|
ZMYND8 |
23613 |
Q9ULU4 |
0.72 |
|
SUMO1 |
7341 |
P63165 |
0.73 |
|
SF1 |
7536 |
Q15637 |
0.75 |
|
U2AF2 |
11338 |
P26368 |
0.76 |
|
SF3A2 |
8175 |
Q15428 |
0.82 |