Gene Symbol | ZNHIT1 |
Entrez ID | 10467 |
Uniprot ID | O43257 |
Description | zinc finger, HIT-type containing 1 |
Chromosomal Location | chr7: 101,217,668-101,224,190 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0031063 |
regulation of histone deacetylation |
Any process that modulates the frequency, rate or extent of the removal of acetyl groups from histones. |
IBA |
BP |
GO:0043486 |
histone exchange |
The replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits. |
IBA |
CC |
GO:0000812 |
Swr1 complex |
A multisubunit protein complex that is involved in chromatin remodeling. It is required for the incorporation of the histone variant H2AZ into chromatin. In S. cerevisiae, the complex contains Swr1p, a Swi2/Snf2-related ATPase, and 12 additional subunits. |
IBA |
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
IDA |
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
MF |
GO:0031491 |
nucleosome binding |
Interacting selectively and non-covalently with a nucleosome, a complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures. |
IBA |
MF |
GO:0042826 |
histone deacetylase binding |
Interacting selectively and non-covalently with the enzyme histone deacetylase. |
IBA |
MF |
GO:0046872 |
metal ion binding |
Interacting selectively and non-covalently with any metal ion. |
IEA |
Domain ID | Description |
---|---|
IPR007529 |
Zinc finger, HIT-type |
Tissue | Cell Type |
---|---|
adrenal gland |
glandular cells |
appendix |
glandular cells |
bronchus |
respiratory epithelial cells |
cerebellum |
Purkinje cells |
cerebral cortex |
neuronal cells |
colon |
endothelial cells |
colon |
glandular cells |
duodenum |
glandular cells |
esophagus |
squamous epithelial cells |
gallbladder |
glandular cells |
lymph node |
non-germinal center cells |
nasopharynx |
respiratory epithelial cells |
pancreas |
exocrine glandular cells |
parathyroid gland |
glandular cells |
placenta |
decidual cells |
placenta |
trophoblastic cells |
rectum |
glandular cells |
skin |
melanocytes |
small intestine |
glandular cells |
thyroid gland |
glandular cells |
urinary bladder |
urothelial cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
TP53 |
7157 |
P04637 |
0.62 |
DAPP1 |
27071 |
Q9UN19 |
0.63 |
KRTAP10-7 |
386675 |
P60409 |
0.63 |
CSNK2B |
1460 |
P67870 |
0.73 |
H2AFZ |
3015 |
P0C0S5 |
0.76 |
MAPK11 |
5600 |
Q15759 |
0.76 |
VPS72 |
6944 |
Q15906 |
0.82 |
RUVBL1 |
8607 |
Q9Y265 |
0.82 |
SRCAP |
10847 |
Q6ZRS2 |
0.82 |
RUVBL2 |
10856 |
Q9Y230 |
0.82 |
DMAP1 |
55929 |
Q9NPF5 |
0.82 |
ACTL6A |
86 |
O96019 |
0.86 |
YEATS4 |
8089 |
O95619 |
0.87 |
ACTR6 |
64431 |
Q9GZN1 |
0.87 |
MAPK14 |
1432 |
Q16539 |
0.88 |
GRB7 |
2886 |
Q14451 |
0.63 |
SH2D1A |
4068 |
O60880 |
0.63 |
UBC |
7316 |
P0CG48 |
0.63 |
TNIP1 |
10318 |
Q15025 |
0.63 |
HINFP |
25988 |
Q9BQA5 |
0.63 |
HIST1H2BA |
255626 |
Q96A08 |
0.63 |
TP53BP1 |
7158 |
Q12888 |
0.68 |
LCA5 |
167691 |
Q86VQ0 |
0.72 |