Gene Symbol | NSA2 |
Entrez ID | 10412 |
Uniprot ID | O95478 |
Description | NSA2, ribosome biogenesis homolog |
Chromosomal Location | chr5: 74,766,991-74,780,113 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0000460 |
maturation of 5.8S rRNA |
Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule. |
IBA |
BP |
GO:0000470 |
maturation of LSU-rRNA |
Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule. |
IBA |
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
IDA |
CC |
GO:0005730 |
nucleolus |
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
IBA|IDA |
CC |
GO:0030687 |
preribosome, large subunit precursor |
A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit. |
IBA |
MF |
GO:0044822 |
poly(A) RNA binding |
Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases. |
IDA |
Domain ID | Description |
---|---|
IPR022309 |
Ribosomal protein S8e/ribosomal biogenesis NSA2 |
UMLS CUI | UMLS Term |
---|---|
C0023892 |
Biliary Cirrhosis |
Tissue | Cell Type |
---|---|
cerebellum |
Purkinje cells |
esophagus |
squamous epithelial cells |
gallbladder |
glandular cells |
kidney |
cells in tubules |
placenta |
trophoblastic cells |
rectum |
glandular cells |
skin |
Langerhans |
stomach |
glandular cells |
testis |
Leydig cells |
tonsil |
squamous epithelial cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
15291743 |
Diao et al. |
2004 |
The molecular characteristics of polycystic ovary syndrome (PCOS) ovary defined by human ovary cDNA microarray |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
RPL27 |
6155 |
P61353 |
0.49 |
NOC2L |
26155 |
Q9Y3T9 |
0.56 |
SDAD1 |
55153 |
Q9NVU7 |
0.56 |
NPM1 |
4869 |
P06748 |
0.63 |
RPS8 |
6202 |
P62241 |
0.63 |
PABPC4 |
8761 |
Q13310 |
0.63 |
ZNF646 |
9726 |
O15015 |
0.63 |
RRS1 |
23212 |
Q15050 |
0.63 |
RPL26L1 |
51121 |
Q9UNX3 |
0.63 |
PTCD3 |
55037 |
Q96EY7 |
0.63 |
MRPS9 |
64965 |
P82933 |
0.63 |
CCDC86 |
79080 |
Q9H6F5 |
0.63 |
TYW5 |
129450 |
A2RUC4 |
0.63 |
LIN28B |
389421 |
Q6ZN17 |
0.63 |
MAGEA9; MAGEA9B |
4108 |
P43362 |
0.63 |
GNL2 |
29889 |
Q13823 |
0.70 |
RSL24D1 |
51187 |
Q9UHA3 |
0.70 |
NLE1 |
54475 |
Q9NVX2 |
0.70 |
RPF2 |
84154 |
Q9H7B2 |
0.73 |
GTPBP4 |
23560 |
Q9BZE4 |
0.79 |
MRTO4 |
51154 |
Q9UKD2 |
0.79 |
RPL5 |
6125 |
P46777 |
0.49 |
EIF2S2 |
8894 |
P20042 |
0.49 |
EBNA1BP2 |
10969 |
Q99848 |
0.49 |
BRIX1 |
55299 |
Q8TDN6 |
0.49 |
DDX24 |
57062 |
Q9GZR7 |
0.49 |
NIFK |
84365 |
Q9BYG3 |
0.49 |
TMEM67 |
91147 |
Q5HYA8 |
0.49 |
CNTROB |
116840 |
Q8N137 |
0.49 |
FTSJ3 |
117246 |
Q8IY81 |
0.49 |
SPICE1 |
152185 |
Q8N0Z3 |
0.49 |
TMEM17 |
200728 |
Q86X19 |
0.49 |
NOP2 |
4839 |
P46087 |
0.56 |
DDX18 |
8886 |
Q9NVP1 |
0.56 |
PUM3 |
9933 |
Q15397 |
0.56 |
NOP56 |
10528 |
O00567 |
0.56 |
PES1 |
23481 |
O00541 |
0.56 |
HIST1H1A |
3024 |
Q02539 |
0.63 |
MNDA |
4332 |
P41218 |
0.63 |
RNF2 |
6045 |
Q99496 |
0.63 |
IRAK3 |
11213 |
Q9Y616 |
0.63 |
ZC3H3 |
23144 |
Q8IXZ2 |
0.63 |
SIRT7 |
51547 |
Q9NRC8 |
0.63 |
PRR11 |
55771 |
Q96HE9 |
0.63 |
NOL12 |
79159 |
Q9UGY1 |
0.63 |
CAMKK1 |
84254 |
Q8N5S9 |
0.72 |
RPL13 |
6137 |
P26373 |
0.73 |
IFI16 |
3428 |
Q16666 |
0.82 |