Gene Symbol | MYL9 |
Entrez ID | 10398 |
Uniprot ID | P24844 |
Description | myosin light chain 9 |
Chromosomal Location | chr20: 36,541,484-36,551,447 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006936 |
muscle contraction |
A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. |
TAS |
BP |
GO:0006937 |
regulation of muscle contraction |
Any process that modulates the frequency, rate or extent of muscle contraction. |
TAS |
BP |
GO:0070527 |
platelet aggregation |
The adhesion of one platelet to one or more other platelets via adhesion molecules. |
IMP |
CC |
GO:0001725 |
stress fiber |
A contractile actin filament bundle that consists of short actin filaments with alternating polarity, cross-linked by alpha-actinin and possibly other actin bundling proteins, and with myosin present in a periodic distribution along the fiber. |
IEA |
CC |
GO:0005829 |
cytosol |
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
TAS |
CC |
GO:0005859 |
muscle myosin complex |
A filament of myosin found in a muscle cell of any type. |
TAS |
CC |
GO:0030018 |
Z disc |
Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached. |
IEA |
MF |
GO:0005509 |
calcium ion binding |
Interacting selectively and non-covalently with calcium ions (Ca2+). |
IEA |
MF |
GO:0008307 |
structural constituent of muscle |
The action of a molecule that contributes to the structural integrity of a muscle fiber. |
TAS |
MF |
GO:0032036 |
myosin heavy chain binding |
Interacting selectively and non-covalently with a heavy chain of a myosin complex. |
IEA |
Domain ID | Description |
---|---|
IPR002048 |
EF-hand domain |
IPR011992 |
EF-hand domain pair |
IPR018247 |
EF-Hand 1, calcium-binding site |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa04022 |
cGMP-PKG signaling pathway |
KEGG |
hsa04024 |
cAMP signaling pathway |
KEGG |
hsa04270 |
Vascular smooth muscle contraction |
KEGG |
hsa04510 |
Focal adhesion |
KEGG |
hsa04530 |
Tight junction |
KEGG |
hsa04670 |
Leukocyte transendothelial migration |
KEGG |
hsa04810 |
Regulation of actin cytoskeleton |
KEGG |
hsa04921 |
Oxytocin signaling pathway |
KEGG |
WP383 |
Striated Muscle Contraction |
WikiPathways |
UMLS CUI | UMLS Term |
---|---|
C0042373 |
Vascular Diseases |
C1527311 |
Brain Edema |
Tissue | Cell Type |
---|---|
skin |
epidermal cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
19141577 |
Kim et al. |
2009 |
Transcriptional Profiling with a Pathway-Oriented Analysis Identifies Dysregulated Molecular Phenotypes in the Endometrium of Patients with Polycystic Ovary Syndrome |
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
PIP4K2B |
8396 |
P78356 |
0.49 |
EIF3I |
8668 |
Q13347 |
0.49 |
EIF2S2 |
8894 |
P20042 |
0.49 |
PIP4K2C |
79837 |
Q8TBX8 |
0.49 |
CDC42BPA |
8476 |
Q5VT25 |
0.52 |
HSPB1 |
3315 |
P04792 |
0.63 |
MCM2 |
4171 |
P49736 |
0.63 |
SP1 |
6667 |
P08047 |
0.63 |
TP53 |
7157 |
P04637 |
0.63 |
TP73 |
7161 |
O15350 |
0.63 |
TP63 |
8626 |
Q9H3D4 |
0.63 |
MYL12A |
10627 |
P19105 |
0.63 |
FBXO25 |
26260 |
Q8TCJ0 |
0.63 |
MYH14 |
79784 |
Q7Z406 |
0.63 |
FOXD3 |
27022 |
Q9UJU5 |
0.72 |
FOXP1 |
27086 |
Q9H334 |
0.72 |
MYH9 |
4627 |
P35579 |
0.82 |
LRRK2 |
120892 |
Q5S007 |
0.82 |