| Gene Symbol | HMG20A |
| Entrez ID | 10363 |
| Uniprot ID | Q9NP66 |
| Description | high mobility group 20A |
| Chromosomal Location | chr15: 77,420,412-77,485,607 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter. |
IEA |
|
BP |
GO:0006325 |
chromatin organization |
Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin. |
NAS |
|
BP |
GO:0006351 |
transcription, DNA-templated |
The cellular synthesis of RNA on a template of DNA. |
IEA |
|
BP |
GO:0006355 |
regulation of transcription, DNA-templated |
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
NAS |
|
BP |
GO:0016569 |
chromatin modification |
The alteration of DNA or protein in chromatin by the covalent addition or removal of chemical groups. |
IEA |
|
BP |
GO:0045665 |
negative regulation of neuron differentiation |
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation. |
IEA |
|
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
NAS |
|
MF |
GO:0003677 |
DNA binding |
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
NAS |
|
MF |
GO:0003700 |
transcription factor activity, sequence-specific DNA binding |
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex. |
NAS |
|
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
|
MF |
GO:0046982 |
protein heterodimerization activity |
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer. |
IEA |
| Domain ID | Description |
|---|---|
|
IPR009071 |
High mobility group box domain |
| UMLS CUI | UMLS Term |
|---|---|
|
C0011860 |
Diabetes Mellitus, Non-Insulin-Dependent |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
appendix |
glandular cells |
|
bone marrow |
hematopoietic cells |
|
breast |
glandular cells |
|
caudate |
glial cells |
|
caudate |
neuronal cells |
|
cerebellum |
cells in granular layer |
|
cerebellum |
cells in molecular layer |
|
cerebellum |
Purkinje cells |
|
cerebral cortex |
endothelial cells |
|
cerebral cortex |
glial cells |
|
cerebral cortex |
neuronal cells |
|
cervix, uterine |
glandular cells |
|
colon |
glandular cells |
|
duodenum |
glandular cells |
|
endometrium |
cells in endometrial stroma |
|
endometrium |
glandular cells |
|
esophagus |
squamous epithelial cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
heart muscle |
myocytes |
|
hippocampus |
glial cells |
|
hippocampus |
neuronal cells |
|
kidney |
cells in glomeruli |
|
lung |
macrophages |
|
lung |
pneumocytes |
|
lymph node |
germinal center cells |
|
nasopharynx |
respiratory epithelial cells |
|
oral mucosa |
squamous epithelial cells |
|
ovary |
ovarian stroma cells |
|
pancreas |
exocrine glandular cells |
|
pancreas |
islets of Langerhans |
|
parathyroid gland |
glandular cells |
|
placenta |
decidual cells |
|
placenta |
trophoblastic cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
skin |
fibroblasts |
|
skin |
keratinocytes |
|
skin |
melanocytes |
|
small intestine |
glandular cells |
|
soft tissue |
adipocytes |
|
spleen |
cells in red pulp |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
thyroid gland |
glandular cells |
|
tonsil |
squamous epithelial cells |
|
urinary bladder |
urothelial cells |
|
vagina |
squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
12734205 |
Wood et al. |
2003 |
The Molecular Phenotype of Polycystic Ovary Syndrome (PCOS) Theca Cells and New Candidate PCOS Genes Defined by Microarray Analysis |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
RPP30 |
10556 |
P78346 |
0.63 |
|
GTF2A1L |
11036 |
Q9UNN4 |
0.63 |
|
RCOR1 |
23186 |
Q9UKL0 |
0.63 |
|
CCDC136 |
64753 |
Q96JN2 |
0.63 |
|
SCNM1 |
79005 |
Q9BWG6 |
0.63 |
|
SYTL4 |
94121 |
Q96C24 |
0.63 |
|
CFAP53 |
220136 |
Q96M91 |
0.63 |
|
RSPH9 |
221421 |
Q9H1X1 |
0.63 |
|
HSPD1 |
3329 |
P10809 |
0.72 |
|
PAWR |
5074 |
Q96IZ0 |
0.72 |
|
RAD51 |
5888 |
Q06609 |
0.72 |
|
RBBP7 |
5931 |
Q16576 |
0.72 |
|
TRIM27 |
5987 |
P14373 |
0.72 |
|
TCF20 |
6942 |
Q9UGU0 |
0.72 |
|
MBD2 |
8932 |
Q9UBB5 |
0.72 |
|
MTA2 |
9219 |
O94776 |
0.72 |
|
PHF14 |
9678 |
O94880 |
0.72 |
|
RAI1 |
10743 |
Q7Z5J4 |
0.72 |
|
GSE1 |
23199 |
Q14687 |
0.72 |
|
HP1BP3 |
50809 |
Q5SSJ5 |
0.72 |
|
PHF21A |
51317 |
Q96BD5 |
0.72 |
|
GATAD2A |
54815 |
Q86YP4 |
0.72 |
|
BCOR |
54880 |
Q6W2J9 |
0.72 |
|
UHRF1BP1 |
54887 |
Q6BDS2 |
0.72 |
|
RCOR3 |
55758 |
Q9P2K3 |
0.72 |
|
GATAD2B |
57459 |
Q8WXI9 |
0.72 |
|
HMG20A |
10363 |
Q9NP66 |
0.73 |
|
ADD1 |
118 |
P35611 |
0.63 |
|
FMNL1 |
752 |
O95466 |
0.63 |
|
ELAVL1 |
1994 |
Q15717 |
0.63 |
|
FGF1 |
2246 |
P05230 |
0.63 |
|
KPNA2 |
3838 |
P52292 |
0.63 |
|
MOV10 |
4343 |
Q9HCE1 |
0.63 |
|
PTH2R |
5746 |
P49190 |
0.63 |
|
SHMT2 |
6472 |
P34897 |
0.63 |
|
SNAI1 |
6615 |
O95863 |
0.63 |
|
RBM7 |
10179 |
Q9Y580 |
0.63 |
|
MAGOHB |
55110 |
Q96A72 |
0.63 |
|
DOK4 |
55715 |
Q8TEW6 |
0.63 |
|
MTA3 |
57504 |
Q9BTC8 |
0.63 |
|
HECW2 |
57520 |
Q9P2P5 |
0.63 |
|
HIST1H2BA |
255626 |
Q96A08 |
0.63 |
|
HTT |
3064 |
P42858 |
0.72 |
|
CDK2AP1 |
8099 |
O14519 |
0.72 |
|
HEMGN |
55363 |
Q9BXL5 |
0.72 |
|
SMAD4 |
4089 |
Q13485 |
0.73 |
|
CCNK |
8812 |
O75909 |
0.73 |
|
HPCAL1 |
3241 |
P37235 |
0.74 |
|
TESC |
54997 |
Q96BS2 |
0.77 |
|
BRAP |
8315 |
Q7Z569 |
0.82 |
|
HMG20B |
10362 |
Q9P0W2 |
0.82 |
|
DTNB |
1838 |
O60941 |
0.85 |
|
HDAC1 |
3065 |
Q13547 |
0.87 |
|
HDAC2 |
3066 |
Q92769 |
0.87 |
|
KDM1A |
23028 |
O60341 |
0.87 |