| Gene Symbol | NPM3 |
| Entrez ID | 10360 |
| Uniprot ID | O75607 |
| Description | nucleophosmin/nucleoplasmin 3 |
| Chromosomal Location | chr10: 101,781,325-101,783,413 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0006364 |
rRNA processing |
Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. |
IEA |
|
BP |
GO:0009303 |
rRNA transcription |
The synthesis of ribosomal RNA (rRNA), any RNA that forms part of the ribosomal structure, from a DNA template. |
IEA |
|
CC |
GO:0005730 |
nucleolus |
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
IEA |
|
MF |
GO:0044822 |
poly(A) RNA binding |
Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases. |
IDA |
| Domain ID | Description |
|---|---|
|
IPR004301 |
Nucleoplasmin family |
|
IPR024057 |
Nucleoplasmin core domain |
| Tissue | Cell Type |
|---|---|
|
bronchus |
respiratory epithelial cells |
|
caudate |
neuronal cells |
|
cerebellum |
Purkinje cells |
|
cerebral cortex |
neuronal cells |
|
cervix, uterine |
squamous epithelial cells |
|
colon |
glandular cells |
|
endometrium |
glandular cells |
|
esophagus |
squamous epithelial cells |
|
gallbladder |
glandular cells |
|
hippocampus |
neuronal cells |
|
kidney |
cells in tubules |
|
oral mucosa |
squamous epithelial cells |
|
pancreas |
exocrine glandular cells |
|
placenta |
decidual cells |
|
placenta |
trophoblastic cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
skin |
keratinocytes |
|
skin |
Langerhans |
|
skin |
melanocytes |
|
skin |
epidermal cells |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
testis |
Leydig cells |
|
tonsil |
squamous epithelial cells |
|
urinary bladder |
urothelial cells |
|
vagina |
squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
12734205 |
Wood et al. |
2003 |
The Molecular Phenotype of Polycystic Ovary Syndrome (PCOS) Theca Cells and New Candidate PCOS Genes Defined by Microarray Analysis |
|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
ATP5B |
506 |
P06576 |
0.49 |
|
EEF1G |
1937 |
P26641 |
0.49 |
|
TPD52L1 |
7164 |
Q16890 |
0.49 |
|
YWHAE |
7531 |
P62258 |
0.49 |
|
ARGLU1 |
55082 |
Q9NWB6 |
0.49 |
|
NPM2 |
10361 |
Q86SE8 |
0.63 |
|
CEP126 |
57562 |
Q9P2H0 |
0.63 |
|
EWSR1 |
2130 |
Q01844 |
0.49 |
|
HSP90AB1 |
3326 |
P08238 |
0.49 |
|
HIST1H2BC; HIST1H2BE; HIST1H2BF; HIST1H2BG; HIST1H2BI |
8339 |
P62807 |
0.49 |
|
PRPF40A |
55660 |
O75400 |
0.49 |
|
AP1G1 |
164 |
O43747 |
0.63 |
|
ATP5F1 |
515 |
P24539 |
0.63 |
|
BARD1 |
580 |
Q99728 |
0.63 |
|
DNM1 |
1759 |
Q05193 |
0.63 |
|
JUN |
3725 |
P05412 |
0.63 |
|
MCM2 |
4171 |
P49736 |
0.63 |
|
MDM2 |
4193 |
Q00987 |
0.63 |
|
WT1 |
7490 |
P19544 |
0.63 |
|
EED |
8726 |
O75530 |
0.63 |
|
IRF2BPL |
64207 |
Q9H1B7 |
0.63 |
|
HNRNPU |
3192 |
Q00839 |
0.72 |
|
RPL10 |
6134 |
P27635 |
0.72 |
|
SUMO2 |
6613 |
P61956 |
0.73 |
|
NCL |
4691 |
P19338 |
0.74 |
|
NPM1 |
4869 |
P06748 |
0.92 |