| Gene Symbol | SRRM1 |
| Entrez ID | 10250 |
| Uniprot ID | Q8IYB3 |
| Description | serine/arginine repetitive matrix 1 |
| Chromosomal Location | chr1: 24,631,716-24,673,267 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0000375 |
RNA splicing, via transesterification reactions |
Splicing of RNA via a series of two transesterification reactions. |
TAS |
|
BP |
GO:0000398 |
mRNA splicing, via spliceosome |
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced. |
IC|TAS |
|
BP |
GO:0006369 |
termination of RNA polymerase II transcription |
The process in which the synthesis of an RNA molecule by RNA polymerase II using a DNA template is completed. |
TAS |
|
BP |
GO:0006405 |
RNA export from nucleus |
The directed movement of RNA from the nucleus to the cytoplasm. |
TAS |
|
BP |
GO:0006406 |
mRNA export from nucleus |
The directed movement of mRNA from the nucleus to the cytoplasm. |
TAS |
|
BP |
GO:0008380 |
RNA splicing |
The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. |
TAS |
|
BP |
GO:0031124 |
mRNA 3'-end processing |
Any process involved in forming the mature 3' end of an mRNA molecule. |
TAS |
|
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
TAS |
|
CC |
GO:0005654 |
nucleoplasm |
That part of the nuclear content other than the chromosomes or the nucleolus. |
IDA|TAS |
|
CC |
GO:0005829 |
cytosol |
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
TAS |
|
CC |
GO:0016363 |
nuclear matrix |
The dense fibrillar network lying on the inner side of the nuclear membrane. |
IEA |
|
CC |
GO:0016607 |
nuclear speck |
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy. |
IEA |
|
CC |
GO:0071013 |
catalytic step 2 spliceosome |
A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs. |
IDA |
|
MF |
GO:0003677 |
DNA binding |
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
IEA |
|
MF |
GO:0044822 |
poly(A) RNA binding |
Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases. |
IDA |
| Domain ID | Description |
|---|---|
|
IPR002483 |
PWI domain |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
|
hsa03013 |
RNA transport |
KEGG |
|
hsa03015 |
mRNA surveillance pathway |
KEGG |
|
WP411 |
mRNA Processing |
WikiPathways |
| Tissue | Cell Type |
|---|---|
|
appendix |
glandular cells |
|
breast |
glandular cells |
|
bronchus |
respiratory epithelial cells |
|
caudate |
neuronal cells |
|
cerebellum |
cells in molecular layer |
|
cerebellum |
Purkinje cells |
|
cerebral cortex |
neuronal cells |
|
cervix, uterine |
glandular cells |
|
colon |
glandular cells |
|
duodenum |
glandular cells |
|
epididymis |
glandular cells |
|
esophagus |
squamous epithelial cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
kidney |
cells in tubules |
|
nasopharynx |
respiratory epithelial cells |
|
oral mucosa |
squamous epithelial cells |
|
pancreas |
exocrine glandular cells |
|
placenta |
decidual cells |
|
placenta |
trophoblastic cells |
|
prostate |
glandular cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
seminal vesicle |
glandular cells |
|
skin |
epidermal cells |
|
small intestine |
glandular cells |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
tonsil |
squamous epithelial cells |
|
urinary bladder |
urothelial cells |
|
vagina |
squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
DHX15 |
1665 |
O43143 |
0.49 |
|
GTF2E1 |
2960 |
P29083 |
0.49 |
|
NUMA1 |
4926 |
Q14980 |
0.49 |
|
RANBP2 |
5903 |
P49792 |
0.49 |
|
NOLC1 |
9221 |
Q14978 |
0.49 |
|
GTF2F1 |
2962 |
P35269 |
0.59 |
|
CHD4 |
1108 |
Q14839 |
0.63 |
|
CNGB1 |
1258 |
Q14028 |
0.63 |
|
CRYBB3 |
1417 |
P26998 |
0.63 |
|
CSNK2B |
1460 |
P67870 |
0.63 |
|
CSTF2 |
1478 |
P33240 |
0.63 |
|
EEF1A1 |
1915 |
P68104 |
0.63 |
|
GTF2I |
2969 |
P78347 |
0.63 |
|
DNAJA1 |
3301 |
P31689 |
0.63 |
|
LMNA |
4000 |
P02545 |
0.63 |
|
HNRNPM |
4670 |
P52272 |
0.63 |
|
NONO |
4841 |
Q15233 |
0.63 |
|
CNOT3 |
4849 |
O75175 |
0.63 |
|
PLRG1 |
5356 |
O43660 |
0.63 |
|
PTBP1 |
5725 |
P26599 |
0.63 |
|
RAD21 |
5885 |
O60216 |
0.63 |
|
UPF1 |
5976 |
Q92900 |
0.63 |
|
RPS5 |
6193 |
P46782 |
0.63 |
|
RPS7 |
6201 |
P62081 |
0.63 |
|
RPS19 |
6223 |
P39019 |
0.63 |
|
SAFB |
6294 |
Q15424 |
0.63 |
|
SFPQ |
6421 |
P23246 |
0.63 |
|
SRSF2 |
6427 |
Q01130 |
0.63 |
|
SRSF5 |
6430 |
Q13243 |
0.63 |
|
SRSF7 |
6432 |
Q16629 |
0.63 |
|
SMARCC2 |
6601 |
Q8TAQ2 |
0.63 |
|
SNRPA1 |
6627 |
P09661 |
0.63 |
|
SNRPB |
6628 |
P14678 |
0.63 |
|
SNRPB2 |
6629 |
P08579 |
0.63 |
|
SNRPC |
6631 |
P09234 |
0.63 |
|
SNRPD2 |
6633 |
P62316 |
0.63 |
|
SNRPD3 |
6634 |
P62318 |
0.63 |
|
SNRPF |
6636 |
P62306 |
0.63 |
|
SOS1 |
6654 |
Q07889 |
0.63 |
|
TOP2B |
7155 |
Q02880 |
0.63 |
|
KMT2D |
8085 |
O14686 |
0.63 |
|
SMC1A |
8243 |
Q14683 |
0.63 |
|
SPOP |
8405 |
O43791 |
0.63 |
|
DHX16 |
8449 |
O60231 |
0.63 |
|
YBX3 |
8531 |
P16989 |
0.63 |
|
EIF3H |
8667 |
O15372 |
0.63 |
|
NRP1 |
8829 |
O14786 |
0.63 |
|
FUBP1 |
8880 |
Q96AE4 |
0.63 |
|
ASH2L |
9070 |
Q9UBL3 |
0.63 |
|
SMC3 |
9126 |
Q9UQE7 |
0.63 |
|
DDX21 |
9188 |
Q9NR30 |
0.63 |
|
EFTUD2 |
9343 |
Q15029 |
0.63 |
|
SNRNP40 |
9410 |
Q96DI7 |
0.63 |
|
BCLAF1 |
9774 |
Q9NYF8 |
0.63 |
|
RBM8A |
9939 |
Q9Y5S9 |
0.63 |
|
OLIG2 |
10215 |
Q13516 |
0.63 |
|
SF3B4 |
10262 |
Q15427 |
0.63 |
|
SAP18 |
10284 |
O00422 |
0.63 |
|
KHDRBS1 |
10657 |
Q07666 |
0.63 |
|
STAG2 |
10735 |
Q8N3U4 |
0.63 |
|
NES |
10763 |
P48681 |
0.63 |
|
SF3B2 |
10992 |
Q13435 |
0.63 |
|
OGFR |
11054 |
Q9NZT2 |
0.63 |
|
CBX3 |
11335 |
Q13185 |
0.63 |
|
DNAJC8 |
22826 |
O75937 |
0.63 |
|
PUF60 |
22827 |
Q9UHX1 |
0.63 |
|
CCT5 |
22948 |
P48643 |
0.63 |
|
PAXIP1 |
22976 |
Q6ZW49 |
0.63 |
|
ACIN1 |
22985 |
Q9UKV3 |
0.63 |
|
SNRNP200 |
23020 |
O75643 |
0.63 |
|
WAPL |
23063 |
Q7Z5K2 |
0.63 |
|
PDS5A |
23244 |
Q29RF7 |
0.63 |
|
SF3B3 |
23450 |
Q15393 |
0.63 |
|
UPF2 |
26019 |
Q9HAU5 |
0.63 |
|
RBMX |
27316 |
P38159 |
0.63 |
|
ZNF638 |
27332 |
Q14966 |
0.63 |
|
PRPF19 |
27339 |
Q9UMS4 |
0.63 |
|
PCF11 |
51585 |
O94913 |
0.63 |
|
PPIL1 |
51645 |
Q9Y3C6 |
0.63 |
|
RBM23 |
55147 |
Q86U06 |
0.63 |
|
PRPF40A |
55660 |
O75400 |
0.63 |
|
ISY1 |
57461 |
Q9ULR0 |
0.63 |
|
NCOA5 |
57727 |
Q9HCD5 |
0.63 |
|
ZC3H14 |
79882 |
Q6PJT7 |
0.63 |
|
DPY30 |
84661 |
Q9C005 |
0.63 |
|
ASB7 |
140460 |
Q9H672 |
0.63 |
|
HIST2H2AA3; HIST2H2AA4 |
723790 |
Q6FI13 |
0.63 |
|
UPF3A |
65110 |
Q9H1J1 |
0.72 |
|
DDX5 |
1655 |
P17844 |
0.73 |
|
PNN |
5411 |
Q9H307 |
0.73 |
|
SRSF3 |
6428 |
P84103 |
0.73 |
|
SRSF4 |
6429 |
Q08170 |
0.73 |
|
SRSF6 |
6431 |
Q13247 |
0.73 |
|
SNRPE |
6635 |
P62304 |
0.73 |
|
DEK |
7913 |
P35659 |
0.73 |
|
PRPF3 |
9129 |
O43395 |
0.73 |
|
RBM39 |
9584 |
Q14498 |
0.73 |
|
NXF1 |
10482 |
Q9UBU9 |
0.73 |
|
PRPF8 |
10594 |
Q6P2Q9 |
0.73 |
|
RBM25 |
58517 |
P49756 |
0.74 |
|
EIF4A3 |
9775 |
P38919 |
0.82 |
|
FUS |
2521 |
P35637 |
0.84 |
|
SRRM2 |
23524 |
Q9UQ35 |
0.84 |
|
YWHAG |
7532 |
P61981 |
0.86 |
|
EWSR1 |
2130 |
Q01844 |
0.49 |
|
EIF3I |
8668 |
Q13347 |
0.49 |
|
RBM14 |
10432 |
Q96PK6 |
0.49 |
|
SUPT16H |
11198 |
Q9Y5B9 |
0.49 |
|
HTATSF1 |
27336 |
O43719 |
0.49 |
|
PAF1 |
54623 |
Q8N7H5 |
0.49 |
|
CLK1 |
1195 |
P49759 |
0.52 |
|
SRPK1 |
6732 |
Q96SB4 |
0.52 |
|
SUMO1 |
7341 |
P63165 |
0.56 |
|
BARD1 |
580 |
Q99728 |
0.63 |
|
CLK2 |
1196 |
P49760 |
0.63 |
|
ELAVL1 |
1994 |
Q15717 |
0.63 |
|
GRK5 |
2869 |
P34947 |
0.63 |
|
IFI16 |
3428 |
Q16666 |
0.63 |
|
ILF2 |
3608 |
Q12905 |
0.63 |
|
NTRK1 |
4914 |
P04629 |
0.63 |
|
SUMO2 |
6613 |
P61956 |
0.63 |
|
SNCA |
6622 |
P37840 |
0.63 |
|
TADA2A |
6871 |
O75478 |
0.63 |
|
ZNF22 |
7570 |
P17026 |
0.63 |
|
SF3A2 |
8175 |
Q15428 |
0.63 |
|
CUL3 |
8452 |
Q13618 |
0.63 |
|
RPL14 |
9045 |
P50914 |
0.63 |
|
MED23 |
9439 |
Q9ULK4 |
0.63 |
|
THRAP3 |
9967 |
Q9Y2W1 |
0.63 |
|
PTBP3 |
9991 |
O95758 |
0.63 |
|
ABI1 |
10006 |
Q8IZP0 |
0.63 |
|
ALYREF |
10189 |
Q86V81 |
0.63 |
|
ZMYND11 |
10771 |
Q15326 |
0.63 |
|
OBSL1 |
23363 |
O75147 |
0.63 |
|
MED4 |
29079 |
Q9NPJ6 |
0.63 |
|
TRA2A |
29896 |
Q13595 |
0.63 |
|
SH3KBP1 |
30011 |
Q96B97 |
0.63 |
|
DDX41 |
51428 |
Q9UJV9 |
0.63 |
|
SIRT7 |
51547 |
Q9NRC8 |
0.63 |
|
LUC7L |
55692 |
Q9NQ29 |
0.63 |
|
CAND1 |
55832 |
Q86VP6 |
0.63 |
|
VPS18 |
57617 |
Q9P253 |
0.63 |
|
MYH7B |
57644 |
A7E2Y1 |
0.63 |
|
LIN28A |
79727 |
Q9H9Z2 |
0.63 |
|
NIFK |
84365 |
Q9BYG3 |
0.63 |
|
ESR1 |
2099 |
P03372 |
0.67 |
|
PIN1 |
5300 |
Q13526 |
0.68 |
|
CSNK2A1 |
1457 |
P68400 |
0.70 |
|
CSNK2A2 |
1459 |
P19784 |
0.72 |
|
MAGOH |
4116 |
P61326 |
0.72 |
|
EPB41L3 |
23136 |
Q9Y2J2 |
0.72 |
|
SRPK3 |
26576 |
Q9UPE1 |
0.72 |
|
SNW1 |
22938 |
Q13573 |
0.82 |
|
RNPS1 |
10921 |
Q15287 |
0.86 |
|
CDC5L |
988 |
Q99459 |
0.88 |
|
SRPK2 |
6733 |
P78362 |
0.88 |