Protein Description

Gene Symbol DCAF7
Entrez ID 10238
Uniprot ID P61962
Description DDB1 and CUL4 associated factor 7
Chromosomal Location chr17: 63,550,461-63,594,266
Ontology GO ID GO Term Definition Evidence

BP

GO:0007275

multicellular organism development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

IEA

BP

GO:0016567

protein ubiquitination

The process in which one or more ubiquitin groups are added to a protein.

IC|IEA

CC

GO:0005654

nucleoplasm

That part of the nuclear content other than the chromosomes or the nucleolus.

IDA

CC

GO:0005737

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

IDA|TAS

CC

GO:0016363

nuclear matrix

The dense fibrillar network lying on the inner side of the nuclear membrane.

IDA

CC

GO:0043234

protein complex

A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.

IDA

CC

GO:0080008

Cul4-RING E3 ubiquitin ligase complex

A ubiquitin ligase complex in which a cullin from the Cul4 family and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein.

IDA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

Domain ID Description

IPR001680

WD40 repeat

IPR015943

WD40/YVTN repeat-like-containing domain

IPR017986

WD40-repeat-containing domain

IPR019775

WD40 repeat, conserved site

No pathways found.

UMLS CUI UMLS Term

C0376634

Craniofacial Abnormalities

No tissues found.

No databases found.

Pubmed ID Author Year Title

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

APP

351

P05067

0.56

CCT6A

908

P40227

0.63

DIAPH1

1729

O60610

0.63

TCP1

6950

P17987

0.63

CCT3

7203

P49368

0.63

DYRK2

8445

Q92630

0.63

CCT7

10574

Q99832

0.63

CCT4

10575

P50991

0.63

CCT2

10576

P78371

0.63

CCT8

10694

P50990

0.63

CCT5

22948

P48643

0.63

HIPK2

28996

Q9H2X6

0.78

DYRK1A

1859

Q13627

0.89

DYRK1B

9149

Q9Y463

0.89

NINL

22981

Q9Y2I6

0.49

B9D2

80776

Q9BPU9

0.49

BARD1

580

Q99728

0.63

CDK2

1017

P24941

0.63

CSNK1A1

1452

P48729

0.63

CSNK1E

1454

P49674

0.63

EPAS1

2034

Q99814

0.63

ILK

3611

Q13418

0.63

JUN

3725

P05412

0.63

NEDD8

4738

Q15843

0.63

RNF2

6045

Q99496

0.63

SKI

6497

P12755

0.63

SUMO2

6613

P61956

0.63

AURKA

6790

O14965

0.63

TFAP2A

7020

P05549

0.63

TP53

7157

P04637

0.63

TRAF3

7187

Q13114

0.63

VCP

7415

P55072

0.63

XPO1

7514

O14980

0.63

YWHAE

7531

P62258

0.63

CUL5

8065

Q93034

0.63

CUL4A

8451

Q13619

0.63

MED23

9439

Q9ULK4

0.63

CEP57

9702

Q86XR8

0.63

COPS6

10980

Q7L5N1

0.63

FBXW11

23291

Q9UKB1

0.63

AUTS2

26053

Q8WXX7

0.63

LATS2

26524

Q9NRM7

0.63

AGO2

27161

Q9UKV8

0.63

WWOX

51741

Q9NZC7

0.63

CEP76

79959

Q8TAP6

0.63

DDB1

100290337

Q16531

0.63

BIRC2

329

Q13490

0.72

BIRC3

330

Q13489

0.72

CSNK2A1

1457

P68400

0.72

CSNK2A2

1459

P19784

0.72

SFN

2810

P31947

0.72

SMAD2

4087

Q15796

0.72

SMAD3

4088

P84022

0.72

PRKACA

5566

P17612

0.72

PRKACB

5567

P22694

0.72

YWHAB

7529

P31946

0.72

YWHAG

7532

P61981

0.72

YWHAZ

7534

P63104

0.72

FAF2

23197

Q96CS3

0.72

ATP13A2

23400

Q9NQ11

0.72

CBX7

23492

O95931

0.72

GTSE1

51512

Q9NYZ3

0.72

PARD3

56288

Q8TEW0

0.72

ZNF703

80139

Q9H7S9

0.73

YWHAH

7533

Q04917

0.86

MAP3K1

4214

Q13233

0.89