Protein Description

Gene Symbol FAM13A
Entrez ID 10144
Uniprot ID O94988
Description family with sequence similarity 13 member A
Chromosomal Location chr4: 88,725,955-89,111,398
Ontology GO ID GO Term Definition Evidence

BP

GO:0007165

signal transduction

The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.

IEA

BP

GO:0043547

positive regulation of GTPase activity

Any process that activates or increases the activity of a GTPase.

IEA

BP

GO:0051056

regulation of small GTPase mediated signal transduction

Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction.

TAS

CC

GO:0005829

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

TAS

MF

GO:0005096

GTPase activator activity

Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.

TAS

Domain ID Description

IPR000198

Rho GTPase-activating protein domain

IPR008936

Rho GTPase activation protein

Pathway ID Pathway Term Pathway Source

WP3624

Lung fibrosis

WikiPathways

UMLS CUI UMLS Term

C0008677

Bronchitis, Chronic

C0024117

Chronic Obstructive Airway Disease

C0206062

Lung Diseases, Interstitial

C1800706

Idiopathic Pulmonary Fibrosis

No tissues found.

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol Entrez ID Uniprot ID Score

RTEL1

51750

Q9NZ71

0.63

MPP1

4354

Q00013

0.72

PCNA

5111

P12004

0.72

PPP2R1A

5518

P30153

0.72

ERP44

23071

Q9BS26

0.72