Gene Symbol | FAM13A |
Entrez ID | 10144 |
Uniprot ID | O94988 |
Description | family with sequence similarity 13 member A |
Chromosomal Location | chr4: 88,725,955-89,111,398 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0007165 |
signal transduction |
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. |
IEA |
BP |
GO:0043547 |
positive regulation of GTPase activity |
Any process that activates or increases the activity of a GTPase. |
IEA |
BP |
GO:0051056 |
regulation of small GTPase mediated signal transduction |
Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction. |
TAS |
CC |
GO:0005829 |
cytosol |
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
TAS |
MF |
GO:0005096 |
GTPase activator activity |
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP. |
TAS |
Domain ID | Description |
---|---|
IPR000198 |
Rho GTPase-activating protein domain |
IPR008936 |
Rho GTPase activation protein |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
WP3624 |
Lung fibrosis |
WikiPathways |
UMLS CUI | UMLS Term |
---|---|
C0008677 |
Bronchitis, Chronic |
C0024117 |
Chronic Obstructive Airway Disease |
C0206062 |
Lung Diseases, Interstitial |
C1800706 |
Idiopathic Pulmonary Fibrosis |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
RTEL1 |
51750 |
Q9NZ71 |
0.63 |
MPP1 |
4354 |
Q00013 |
0.72 |
PCNA |
5111 |
P12004 |
0.72 |
PPP2R1A |
5518 |
P30153 |
0.72 |
ERP44 |
23071 |
Q9BS26 |
0.72 |