Protein Description

Gene Symbol RANBP9
Entrez ID 10048
Uniprot ID Q96S59
Description RAN binding protein 9
Chromosomal Location chr6: 13,621,498-13,711,564
Ontology GO ID GO Term Definition Evidence

BP

GO:0006461

protein complex assembly

The aggregation, arrangement and bonding together of a set of components to form a protein complex.

TAS

BP

GO:0007020

microtubule nucleation

The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation).

NAS

BP

GO:0007411

axon guidance

The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.

TAS

BP

GO:0070373

negative regulation of ERK1 and ERK2 cascade

Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.

IMP

CC

GO:0005634

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

IDA

CC

GO:0005737

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

IDA

CC

GO:0005829

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

TAS

CC

GO:0005875

microtubule associated complex

Any multimeric complex connected to a microtubule.

TAS

CC

GO:0005886

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

IEA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0008536

Ran GTPase binding

Interacting selectively and non-covalently with Ran, a conserved Ras-like GTP-binding protein, implicated in nucleocytoplasmic transport, cell cycle progression, spindle assembly, nuclear organization and nuclear envelope (NE) assembly.

TAS

MF

GO:0019899

enzyme binding

Interacting selectively and non-covalently with any enzyme.

IPI

Domain ID Description

IPR001870

B30.2/SPRY domain

IPR003877

SPRY domain

IPR006594

LIS1 homology motif

IPR006595

CTLH, C-terminal LisH motif

IPR013144

CRA domain

IPR013320

Concanavalin A-like lectin/glucanase domain

IPR024964

CTLH/CRA C-terminal to LisH motif domain

Pathway ID Pathway Term Pathway Source

WP2380

Brain-Derived Neurotrophic Factor (BDNF) signaling pathway

WikiPathways

No diseases found.

Tissue Cell Type

adrenal gland

glandular cells

cerebellum

Purkinje cells

cerebral cortex

neuronal cells

colon

endothelial cells

esophagus

squamous epithelial cells

gallbladder

glandular cells

heart muscle

myocytes

hippocampus

neuronal cells

kidney

cells in tubules

pancreas

islets of Langerhans

placenta

decidual cells

testis

cells in seminiferous ducts

testis

Leydig cells

tonsil

squamous epithelial cells

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol Entrez ID Uniprot ID Score

ESR1

2099

P03372

0.56

THRA

7067

P10827

0.56

APP

351

P05067

0.63

CCND1

595

P24385

0.63

FLNC

2318

Q14315

0.63

KTN1

3895

Q86UP2

0.63

ABLIM1

3983

O14639

0.63

LRP1

4035

Q07954

0.63

SMAD9

4093

O15198

0.63

MYH10

4628

P35580

0.63

NTRK2

4915

Q16620

0.63

PRKACA

5566

P17612

0.63

SCN1B

6324

Q07699

0.63

SPTB

6710

P11277

0.63

TFAP2A

7020

P05549

0.63

UCHL1

7345

P09936

0.63

YWHAB

7529

P31946

0.63

YWHAE

7531

P62258

0.63

PIAS1

8554

O75925

0.63

FAM127A

8933

O15255

0.63

HDAC6

10013

Q9UBN7

0.63

NCOA6

23054

Q14686

0.63

SYNE2

23224

Q8WXH0

0.63

ARMC8

25852

Q8IUR7

0.63

PTPN23

25930

Q9H3S7

0.63

GIT1

28964

Q9Y2X7

0.63

ATP5SL

55101

Q9NW81

0.63

TSR1

55720

Q2NL82

0.63

EXOC2

55770

Q96KP1

0.63

MIB1

57534

Q86YT6

0.63

ANKRD20A1

84210

Q5TYW2

0.63

TXLNA

200081

P40222

0.63

CCDC88C

440193

Q9P219

0.63

TP73

7161

O15350

0.68

APC

324

P25054

0.70

CDK11B

984

P21127

0.70

COPS5

10987

Q92905

0.72

TFRC

7037

P02786

0.73

MAEA

10296

Q7L5Y9

0.73

RMND5A

64795

Q9H871

0.73

NR3C1

2908

P04150

0.76

ITGAL

3683

P20701

0.76

CALB1

793

P05937

0.78

ITGB2

3689

P05107

0.78

MET

4233

P08581

0.79

S100A7

6278

P31151

0.79

USP11

8237

P51784

0.79

PPP1CC

5501

P36873

0.82

RPS27

6232

P42677

0.82

RAN

5901

P62826

0.84

RANBP9

10048

Q96S59

0.85

MKLN1

4289

Q9UL63

0.87

AR

367

P10275

0.88

GID8

54994

Q9NWU2

0.88

DCTN1

1639

Q14203

0.49

DDX1

1653

Q92499

0.49

DYNC1H1

1778

Q14204

0.49

EEF1A1

1915

P68104

0.49

NGFR

4804

P08138

0.49

PSMC3

5702

P17980

0.49

DCTN2

10540

Q13561

0.49

DDB1

100290337

Q16531

0.49

SOS1

6654

Q07889

0.52

ADAP2

55803

Q9NPF8

0.56

AIRE

326

O43918

0.63

BRCA1

672

P38398

0.63

CBS

875

P35520

0.63

CD4

920

P01730

0.63

CSNK1E

1454

P49674

0.63

CSNK2A2

1459

P19784

0.63

DMD

1756

P11532

0.63

DRD1

1812

P21728

0.63

GDNF

2668

P39905

0.63

GRK5

2869

P34947

0.63

HLA-DPB1

3115

P04440

0.63

HNF4G

3174

Q14541

0.63

ITGB1

3688

P05556

0.63

JUN

3725

P05412

0.63

SMAD2

4087

Q15796

0.63

SMAD3

4088

P84022

0.63

MMP7

4316

P09237

0.63

NEDD8

4738

Q15843

0.63

NOTCH1

4851

P46531

0.63

NTRK1

4914

P04629

0.63

PPARD

5467

Q03181

0.63

PPARG

5468

P37231

0.63

PRG2

5553

P13727

0.63

PRKCD

5580

Q05655

0.63

PRKCG

5582

P05129

0.63

MAPK6

5597

Q16659

0.63

PSMD13

5719

Q9UNM6

0.63

RPS12

6206

P25398

0.63

RPS13

6207

P62277

0.63

SFRP2

6423

Q96HF1

0.63

SKI

6497

P12755

0.63

SOX2

6657

P48431

0.63

SPP1

6696

P10451

0.63

TDGF1

6997

P13385

0.63

SUMO1

7341

P63165

0.63

FXR1

8087

P51114

0.63

CACNA1G

8913

O43497

0.63

NCOR2

9612

Q9Y618

0.63

TUBA1B

10376

P68363

0.63

UBE2C

11065

O00762

0.63

MED4

29079

Q9NPJ6

0.63

RPS27L

51065

Q71UM5

0.63

MRPL4

51073

Q9BYD3

0.63

MPHOSPH8

54737

Q99549

0.63

CLEC7A

64581

Q9BXN2

0.63

WNK1

65125

Q9H4A3

0.63

UBE2Z

65264

Q9H832

0.63

WDR26

80232

Q9H7D7

0.63

SLX4

84464

Q8IY92

0.63

UNK

85451

Q9C0B0

0.63

GLIPR1L2

144321

Q4G1C9

0.63

DDX4

54514

Q9NQI0

0.65

ADAP1

11033

O75689

0.68

ARRB1

408

P49407

0.72

ILK

3611

Q13418

0.72

PMS1

5378

P54277

0.72

EPB41L3

23136

Q9Y2J2

0.72

LTB4R2

56413

Q9NPC1

0.72

NAF1

92345

Q96HR8

0.72

HMBS

3145

P08397

0.73

PPP1CA

5499

P62136

0.73

UBE2I

7329

P63279

0.73

L1CAM

3897

P32004

0.74

LLGL1

3996

Q15334

0.75

TGFBR1

7046

P36897

0.75

THRB

7068

P10828

0.75

SPAG8

26206

Q99932

0.75

FMR1

2332

Q06787

0.76

RNPS1

10921

Q15287

0.76

USP42

84132

Q9H9J4

0.76

HIPK2

28996

Q9H2X6

0.77

ENTPD1

953

P49961

0.78

DISC1

27185

Q9NRI5

0.78

DYRK1B

9149

Q9Y463

0.79

RAF1

5894

P04049

0.82

TP53

7157

P04637

0.82

BACE1

23621

P56817

0.82

AXL

558

P30530

0.84

TRAF6

7189

Q9Y4K3

0.87

OPRM1

4988

P35372

0.88