Gene Symbol | ENTPD6 |
Entrez ID | 955 |
Uniprot ID | O75354 |
Description | ectonucleoside triphosphate diphosphohydrolase 6 (putative) |
Chromosomal Location | chr20: 25,195,693-25,226,729 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0032026 |
response to magnesium ion |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus. |
IEA |
BP |
GO:0051592 |
response to calcium ion |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus. |
IEA |
CC |
GO:0000139 |
Golgi membrane |
The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
IEA |
CC |
GO:0005615 |
extracellular space |
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. |
IEA |
CC |
GO:0005886 |
plasma membrane |
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
IEA |
CC |
GO:0009986 |
cell surface |
The external part of the cell wall and/or plasma membrane. |
IEA |
CC |
GO:0016021 |
integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IEA |
CC |
GO:0070062 |
extracellular exosome |
A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. |
IDA |
MF |
GO:0008894 |
guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity |
Catalysis of the reaction: guanosine 5'-triphosphate,3'-diphosphate + H2O = guanosine 5'-diphosphate,3'-diphosphate + phosphate. |
IEA |
MF |
GO:0017111 |
nucleoside-triphosphatase activity |
Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate. |
IEA |
MF |
GO:0045134 |
uridine-diphosphatase activity |
Catalysis of the reaction: UDP + H2O = UMP + phosphate. |
IEA |
Domain ID | Description |
---|---|
IPR000407 |
Nucleoside phosphatase GDA1/CD39 |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa00230 |
Purine metabolism |
KEGG |
hsa00240 |
Pyrimidine metabolism |
KEGG |
UMLS CUI | UMLS Term |
---|---|
C0036631 |
Seminoma |
C2607914 |
Allergic Rhinitis (Disorder) |
Tissue | Cell Type |
---|---|
adrenal gland |
glandular cells |
appendix |
glandular cells |
appendix |
lymphoid tissue |
breast |
glandular cells |
bronchus |
respiratory epithelial cells |
cerebellum |
Purkinje cells |
cervix, uterine |
glandular cells |
cervix, uterine |
squamous epithelial cells |
colon |
glandular cells |
duodenum |
glandular cells |
endometrium |
glandular cells |
esophagus |
squamous epithelial cells |
fallopian tube |
glandular cells |
gallbladder |
glandular cells |
kidney |
cells in tubules |
oral mucosa |
squamous epithelial cells |
pancreas |
exocrine glandular cells |
pancreas |
islets of Langerhans |
parathyroid gland |
glandular cells |
rectum |
glandular cells |
skin |
Langerhans |
skin |
epidermal cells |
small intestine |
glandular cells |
spleen |
cells in red pulp |
spleen |
cells in white pulp |
testis |
Leydig cells |
thyroid gland |
glandular cells |
tonsil |
germinal center cells |
tonsil |
non-germinal center cells |
urinary bladder |
urothelial cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
ATXN1 |
6310 |
P54253 |
0.63 |
GSK3B |
2932 |
P49841 |
0.63 |
PON2 |
5445 |
Q15165 |
0.63 |
NAAA |
27163 |
Q02083 |
0.63 |
SIAE |
54414 |
Q9HAT2 |
0.63 |
SUSD4 |
55061 |
Q5VX71 |
0.63 |
TMEM25 |
84866 |
Q86YD3 |
0.63 |
CANT1 |
124583 |
Q8WVQ1 |
0.63 |
HTR3C |
170572 |
Q8WXA8 |
0.63 |
RAB5A |
5868 |
P20339 |
0.72 |
RACGAP1 |
29127 |
Q9H0H5 |
0.72 |