| Gene Symbol | ENTPD6 |
| Entrez ID | 955 |
| Uniprot ID | O75354 |
| Description | ectonucleoside triphosphate diphosphohydrolase 6 (putative) |
| Chromosomal Location | chr20: 25,195,693-25,226,729 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
BP | GO:0032026 | response to magnesium ion |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus. | IEA |
BP | GO:0051592 | response to calcium ion |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus. | IEA |
CC | GO:0000139 | Golgi membrane |
The lipid bilayer surrounding any of the compartments of the Golgi apparatus. | IEA |
CC | GO:0005615 | extracellular space |
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. | IEA |
CC | GO:0005886 | plasma membrane |
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. | IEA |
CC | GO:0009986 | cell surface |
The external part of the cell wall and/or plasma membrane. | IEA |
CC | GO:0016021 | integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. | IEA |
CC | GO:0070062 | extracellular exosome |
A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. | IDA |
MF | GO:0008894 | guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity |
Catalysis of the reaction: guanosine 5'-triphosphate,3'-diphosphate + H2O = guanosine 5'-diphosphate,3'-diphosphate + phosphate. | IEA |
MF | GO:0017111 | nucleoside-triphosphatase activity |
Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate. | IEA |
MF | GO:0045134 | uridine-diphosphatase activity |
Catalysis of the reaction: UDP + H2O = UMP + phosphate. | IEA |
| Domain ID | Description |
|---|---|
IPR000407 | Nucleoside phosphatase GDA1/CD39 |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
hsa00230 | Purine metabolism | KEGG |
hsa00240 | Pyrimidine metabolism | KEGG |
| UMLS CUI | UMLS Term |
|---|---|
C0036631 | Seminoma |
C2607914 | Allergic Rhinitis (Disorder) |
| Tissue | Cell Type |
|---|---|
adrenal gland | glandular cells |
appendix | glandular cells |
appendix | lymphoid tissue |
breast | glandular cells |
bronchus | respiratory epithelial cells |
cerebellum | Purkinje cells |
cervix, uterine | glandular cells |
cervix, uterine | squamous epithelial cells |
colon | glandular cells |
duodenum | glandular cells |
endometrium | glandular cells |
esophagus | squamous epithelial cells |
fallopian tube | glandular cells |
gallbladder | glandular cells |
kidney | cells in tubules |
oral mucosa | squamous epithelial cells |
pancreas | exocrine glandular cells |
pancreas | islets of Langerhans |
parathyroid gland | glandular cells |
rectum | glandular cells |
skin | Langerhans |
skin | epidermal cells |
small intestine | glandular cells |
spleen | cells in red pulp |
spleen | cells in white pulp |
testis | Leydig cells |
thyroid gland | glandular cells |
tonsil | germinal center cells |
tonsil | non-germinal center cells |
urinary bladder | urothelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
22617121 | Ouandaogo et al. | 2012 | Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
22951915 | Haozi et al. | 2012 | Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
ATXN1 | 6310 | P54253 | 0.63 |
GSK3B | 2932 | P49841 | 0.63 |
PON2 | 5445 | Q15165 | 0.63 |
NAAA | 27163 | Q02083 | 0.63 |
SIAE | 54414 | Q9HAT2 | 0.63 |
SUSD4 | 55061 | Q5VX71 | 0.63 |
TMEM25 | 84866 | Q86YD3 | 0.63 |
CANT1 | 124583 | Q8WVQ1 | 0.63 |
HTR3C | 170572 | Q8WXA8 | 0.63 |
RAB5A | 5868 | P20339 | 0.72 |
RACGAP1 | 29127 | Q9H0H5 | 0.72 |