Protein Description

Gene Symbol FCHSD2
Entrez ID 9873
Uniprot ID O94868
Description FCH and double SH3 domains 2
Chromosomal Location chr11: 72,836,745-73,142,261
Ontology GO ID GO Term Definition Evidence

BP

GO:0007274

neuromuscular synaptic transmission

The process of communication from a neuron to a muscle, across a synapse.

IBA

BP

GO:0030833

regulation of actin filament polymerization

Any process that modulates the frequency, rate or extent of the assembly of actin filaments by the addition of actin monomers to a filament.

IBA

CC

GO:0031594

neuromuscular junction

The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.

IBA

CC

GO:0055037

recycling endosome

An organelle consisting of a network of tubules that functions in targeting molecules, such as receptors transporters and lipids, to the plasma membrane.

IBA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

Domain ID Description

IPR001060

FCH domain

IPR001452

SH3 domain

IPR027267

Arfaptin homology (AH) domain/BAR domain

IPR031160

F-BAR domain

No pathways found.

UMLS CUI UMLS Term

C0010346

Crohn Disease

C3495559

Juvenile Arthritis

No tissues found.

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

CHKA

1119

P35790

0.63

WAS

7454

P42768

0.63

WASL

8976

O00401

0.63

CCT2

10576

P78371

0.63

DAPP1

27071

Q9UN19

0.63

ABCF3

55324

Q9NUQ8

0.63

CFAP36

112942

Q96G28

0.63

C2orf73

129852

Q8N5S3

0.63

FAM9B

171483

Q8IZU0

0.63

CCDC158

339965

Q5M9N0

0.63

CCDC85B

11007

Q15834

0.73

MTUS2

23281

Q5JR59

0.73

CASK

8573

O14936

0.75

VCP

7415

P55072

0.76

ELAVL1

1994

Q15717

0.63

HSPA5

3309

P11021

0.63

HSP90AB1

3326

P08238

0.63

KIFC3

3801

Q9BVG8

0.63

HTRA1

5654

Q92743

0.63

SH3BGR

6450

P55822

0.63

ITSN1

6453

Q15811

0.63

SRP72

6731

O76094

0.63

PDE4DIP

9659

Q5VU43

0.63

UBD

10537

O15205

0.63

ITSN2

50618

Q9NZM3

0.63

C9orf78

51759

Q9NZ63

0.63

VCPIP1

80124

Q96JH7

0.63

MSL1

339287

Q68DK7

0.63

MAGI1

9223

Q96QZ7

0.79