Gene Symbol | GUCA1C |
Entrez ID | 9626 |
Uniprot ID | O95843 |
Description | guanylate cyclase activator 1C |
Chromosomal Location | chr3: 108,907,792-108,953,895 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0007165 |
signal transduction |
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. |
TAS |
BP |
GO:0007601 |
visual perception |
The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image. |
IEA |
BP |
GO:0022400 |
regulation of rhodopsin mediated signaling pathway |
Any process that modulates the frequency, rate or extent of rhodopsin-mediated signaling. |
TAS |
BP |
GO:0031284 |
positive regulation of guanylate cyclase activity |
Any process that activates or increases the frequency, rate or extent of guanylate cyclase activity. |
IEA |
CC |
GO:0097381 |
photoreceptor disc membrane |
Ovally-shaped membranous stack located inside the photoreceptor outer segment, and containing densely packed molecules of the photoreceptor protein rhodopsin that traverse the lipid bilayer. Disc membranes are apparently derived from the plasma membrane in the region of the cilium that connects the photoreceptor outer segment to the inner segment. |
TAS |
MF |
GO:0005509 |
calcium ion binding |
Interacting selectively and non-covalently with calcium ions (Ca2+). |
IEA |
MF |
GO:0008048 |
calcium sensitive guanylate cyclase activator activity |
Binds to and increases the activity of guanylate cyclase in response to a change in calcium ion concentration. |
IEA |
Domain ID | Description |
---|---|
IPR002048 |
EF-hand domain |
IPR011992 |
EF-hand domain pair |
IPR018247 |
EF-Hand 1, calcium-binding site |
IPR032992 |
Guanylyl cyclase-activating protein 3 |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa04744 |
Phototransduction |
KEGG |
Pubmed ID | Author | Year | Title |
---|---|---|---|
15598877 |
Wood et al. |
2005 |
Valproate-induced alterations in human theca cell gene expression: clues to the association between valproate use and metabolic side effects |