PCOSBase

Protein Description

Ontology	GO ID	GO Term	Definition	Evidence
BP	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.	TAS
BP	GO:0007067	mitotic nuclear division	A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.	IEA
BP	GO:0051301	cell division	The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.	IEA
CC	GO:0005654	nucleoplasm	That part of the nuclear content other than the chromosomes or the nucleolus.	TAS
MF	GO:0005515	protein binding	Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).	IPI

Pathway ID	Pathway Term	Pathway Source
hsa04115	p53 signaling pathway	KEGG
hsa05206	MicroRNAs in cancer	KEGG
WP2431	Spinal Cord Injury	WikiPathways
WP1530	miRNA Regulation of DNA Damage Response	WikiPathways

UMLS CUI	UMLS Term
C0024121	Lung Neoplasms

Tissue	Cell Type
adrenal gland	glandular cells
appendix	glandular cells
breast	glandular cells
bronchus	respiratory epithelial cells
caudate	neuronal cells
cerebral cortex	neuronal cells
colon	peripheral nerve/ganglion
duodenum	glandular cells
epididymis	glandular cells
gallbladder	glandular cells
hippocampus	neuronal cells
kidney	cells in tubules
oral mucosa	squamous epithelial cells
pancreas	islets of Langerhans
placenta	decidual cells
placenta	trophoblastic cells
salivary gland	glandular cells
skeletal muscle	myocytes
small intestine	glandular cells
smooth muscle	smooth muscle cells
soft tissue	adipocytes
stomach	glandular cells
testis	cells in seminiferous ducts

Pubmed ID	Author	Year	Title
15820804	Oksjoki et al.	2005	Molecular profiling of polycystic ovaries for markers of cell invasion and matrix turnover

Gene Symbol	Entrez ID	Uniprot ID	Score
MT-CO2	4513	P00403	0.52
PPP2CA	5515	P67775	0.52
APP	351	P05067	0.56
CDK5	1020	Q00535	0.62
CDK2	1017	P24941	0.63
EEF1G	1937	P26641	0.63
GRN	2896	P28799	0.63
PPP2R5C	5527	Q13362	0.63
PPP2R5D	5528	Q14738	0.63
TFAP2C	7022	Q92754	0.63
TP73	7161	O15350	0.63
CUL4B	8450	Q13620	0.63
CUL4A	8451	Q13619	0.63
PNMA1	9240	Q8ND90	0.63
RBPMS	11030	Q93062	0.63
ZZEF1	23140	O43149	0.63
LARP1	23367	Q6PKG0	0.63
TFIP11	24144	Q9UBB9	0.63
PAK7	57144	Q9P286	0.63
HMBOX1	79618	Q6NT76	0.63
HECTD3	79654	Q5T447	0.63
LZTS2	84445	Q9BRK4	0.63
KRT40	125115	Q6A162	0.63
SPERT	220082	Q8NA61	0.63
KRTAP10-7	386675	P60409	0.63
PPP2R5E	5529	Q16537	0.70
CDKN2A	1029	P42771	0.79
LARP1B	55132	Q659C4	0.82
MDM2	4193	Q00987	0.85
PPP2R4	5524	Q15257	0.87
TP53	7157	P04637	0.96
PPP2R1A	5518	P30153	0.56
LTBP3	4054	Q9NS15	0.63
MOV10	4343	Q9HCE1	0.63
NFATC4	4776	Q14934	0.63
NXF1	10482	Q9UBU9	0.63
PLEKHA4	57664	Q9H4M7	0.63
SHKBP1	92799	Q8TBC3	0.63
CPSF4L	642843	A6NMK7	0.63
TNIP1	10318	Q15025	0.85
GAK	2580	O14976	0.88