PCOSBase

Protein Description

Gene Symbol	BAG2
Entrez ID	9532
Uniprot ID	O95816
Description	BCL2 associated athanogene 2
Chromosomal Location	chr6: 57,172,326-57,189,833

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Ontology	GO ID	GO Term	Definition	Evidence
BP	GO:0006457	protein folding	The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.	TAS
BP	GO:0019538	protein metabolic process	The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.	IDA
BP	GO:0050790	regulation of catalytic activity	Any process that modulates the activity of an enzyme.	IEA
BP	GO:1900034	regulation of cellular response to heat	Any process that modulates the frequency, rate or extent of cellular response to heat.	TAS
CC	GO:0005829	cytosol	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.	TAS
MF	GO:0000774	adenyl-nucleotide exchange factor activity	Stimulates the hydrolysis and exchange of adenyl nucleotides by other proteins.	TAS
MF	GO:0051087	chaperone binding	Interacting selectively and non-covalently with a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.	IEA

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Domain ID	Description
IPR003103	BAG domain

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Pathway ID	Pathway Term	Pathway Source
hsa04141	Protein processing in endoplasmic reticulum	KEGG

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No diseases found.

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Tissue	Cell Type
appendix	lymphoid tissue
smooth muscle	smooth muscle cells

No databases found.

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Pubmed ID	Author	Year	Title
19141577	Kim et al.	2009	Transcriptional Profiling with a Pathway-Oriented Analysis Identifies Dysregulated Molecular Phenotypes in the Endometrium of Patients with Polycystic Ovary Syndrome
22951915	Haozi et al.	2012	Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol	Entrez ID	Uniprot ID	Score
HSF2	3298	Q03933	0.49
MCM5	4174	P33992	0.49
MLF1	4291	P58340	0.49
MOS	4342	P00540	0.49
PSMD2	5708	Q13200	0.49
RAF1	5894	P04049	0.49
REC8	9985	O95072	0.49
NUDCD3	23386	Q8IVD9	0.49
CACYBP	27101	Q9HB71	0.49
FKBPL	63943	Q9UIM3	0.49
AARSD1	80755	Q9BTE6	0.49
EIF2AK4	440275	Q9P2K8	0.49
UBC	7316	P0CG48	0.55
HSPA4	3308	P34932	0.56
DARS	1615	P14868	0.63
DHX9	1660	Q08211	0.63
EPRS	2058	P07814	0.63
HNRNPA1	3178	P09651	0.63
HNRNPU	3192	Q00839	0.63
IARS	3376	P41252	0.63
ILF3	3609	Q12906	0.63
NCL	4691	P19338	0.63
PCCA	5095	P05165	0.63
QARS	5859	P47897	0.63
RPL10	6134	P27635	0.63
RPS8	6202	P62241	0.63
RPS13	6207	P62277	0.63
RPS16	6217	P62249	0.63
RPS18	6222	P62269	0.63
RPS23	6228	P62266	0.63
UBA52	7311	P62987	0.63
XRCC5	7520	P13010	0.63
TUBA1B	10376	P68363	0.63
SYNCRIP	10492	O60506	0.63
AHNAK	79026	Q09666	0.63
LRRK2	120892	Q5S007	0.63
TUBB	203068	P07437	0.63
HNRNPM	4670	P52272	0.67
DNAJB1	3337	P25685	0.72
STXBP2	6813	Q15833	0.72
DNAJB6	10049	O75190	0.72
TAB1	10454	Q15750	0.72
PINK1	65018	Q9BXM7	0.78
DNAJC7	7266	Q99615	0.82
HSPA1A	3303	P0DMV8	0.86
HSPA1B	3304	P0DMV9	0.86
BAG2	9532	O95816	0.92
AICDA	57379	Q9GZX7	0.07
CLCN2	1181	P51788	0.49
NPHP1	4867	O15259	0.49
STIL	6491	Q15468	0.49
SIM2	6493	Q14190	0.49
SMARCD2	6603	Q92925	0.49
IKBKE	9641	Q14164	0.49
KIAA0753	9851	Q2KHM9	0.49
NUDC	10726	Q9Y266	0.49
LATS2	26524	Q9NRM7	0.49
MKS1	54903	Q9NXB0	0.49
DET1	55070	Q7L5Y6	0.49
NAT10	55226	Q9H0A0	0.49
AHSA2	130872	Q719I0	0.49
EVC2	132884	Q86UK5	0.49
TET3	200424	O43151	0.49
NPHP4	261734	O75161	0.49
POC1B	282809	Q8TC44	0.49
BTRC	8945	Q9Y297	0.52
MAPKAPK2	9261	P49137	0.55
NOTCH3	4854	Q9UM47	0.56
ADRBK1	156	P25098	0.63
BCL3	602	P20749	0.63
CDK2	1017	P24941	0.63
CDK4	1019	P11802	0.63
CDK5	1020	Q00535	0.63
CDK9	1025	P50750	0.63
CFTR	1080	P13569	0.63
CRY2	1408	Q49AN0	0.63
CSK	1445	P41240	0.63
CSNK1A1	1452	P48729	0.63
CSNK1E	1454	P49674	0.63
CSNK2A2	1459	P19784	0.63
EGFR	1956	P00533	0.63
EPAS1	2034	Q99814	0.63
KCNH2	3757	Q12809	0.63
LGALS3BP	3959	Q08380	0.63
MCM2	4171	P49736	0.63
NFKB1	4790	P19838	0.63
NFKBIB	4793	Q15653	0.63
NFKBIE	4794	O00221	0.63
NOS2	4843	P35228	0.63
NPM1	4869	P06748	0.63
PARK2	5071	O60260	0.63
PHKG2	5261	P15735	0.63
PRKAA1	5562	Q13131	0.63
PRKACB	5567	P22694	0.63
PRKY	5616	O43930	0.63
RPA1	6117	P27694	0.63
RPA2	6118	P15927	0.63
RPA3	6119	P35244	0.63
RPS6KA1	6195	Q15418	0.63
RPS6KB2	6199	Q9UBS0	0.63
SOX2	6657	P48431	0.63
STK4	6789	Q13043	0.63
TRAF6	7189	Q9Y4K3	0.63
VCP	7415	P55072	0.63
STK24	8428	Q9Y6E0	0.63
CUL3	8452	Q13618	0.63
BAG3	9531	O95817	0.63
CUL7	9820	Q14999	0.63
DNAJC6	9829	O75061	0.63
PSMD6	9861	Q15008	0.63
PAN2	9924	Q504Q3	0.63
OXSR1	9943	O95747	0.63
HDAC5	10014	Q9UQL6	0.63
PPIH	10465	O43447	0.63
STK25	10494	O00506	0.63
SLU7	10569	O95391	0.63
TUBGCP2	10844	Q9BSJ2	0.63
PTP4A3	11156	O75365	0.63
OBSL1	23363	O75147	0.63
TARDBP	23435	Q13148	0.63
SRRM2	23524	Q9UQ35	0.63
PRAME	23532	P78395	0.63
METTL21B	25895	Q96AZ1	0.63
MED9	55090	Q9NWA0	0.63
MED29	55588	Q9NX70	0.63
OTUB1	55611	Q96FW1	0.63
AMBRA1	55626	Q9C0C7	0.63
RIOK2	55781	Q9BVS4	0.63
PPP2R2D	55844	Q66LE6	0.63
CCAR2	57805	Q8N163	0.63
STK33	65975	Q9BYT3	0.63
WDR77	79084	Q9BQA1	0.63
LRRK1	79705	Q38SD2	0.63
WDR76	79968	Q9H967	0.63
WDR83	84292	Q9BRX9	0.63
TP53RK	112858	Q96S44	0.63
MED19	219541	A0JLT2	0.63
ARAF	369	P10398	0.72
BUB1B	701	O60566	0.72
DAPK1	1612	P53355	0.72
FN1	2335	P02751	0.72
XRCC6	2547	P12956	0.72
HSPA5	3309	P11021	0.72
HSP90AA1	3320	P07900	0.72
IRAK1	3654	P51617	0.72
JAK3	3718	P52333	0.72
LAMB3	3914	Q13751	0.72
LIMK2	3985	P53671	0.72
MAP3K1	4214	Q13233	0.72
MAP3K3	4215	Q99759	0.72
NFKB2	4791	Q00653	0.72
PPP2R2C	5522	Q9Y2T4	0.72
RELA	5970	Q04206	0.72
SGTA	6449	O43765	0.72
STRN	6801	O43815	0.72
TNFRSF1A	7132	P19438	0.72
TNFRSF1B	7133	P20333	0.72
TRAF1	7185	Q13077	0.72
TRAF2	7186	Q12933	0.72
TTC1	7265	Q99614	0.72
TYK2	7297	P29597	0.72
TFEB	7942	P19484	0.72
SHFM1	7979	P60896	0.72
OFD1	8481	O75665	0.72
MAP3K14	9020	Q99558	0.72
TOMM40	10452	O96008	0.72
STIP1	10963	P31948	0.72
TAB2	23118	Q9NYJ8	0.72
SIK2	23235	Q9H0K1	0.72
HDAC11	79885	Q96DB2	0.72
NLRP5	126206	P59047	0.72
WDR62	284403	O43379	0.72
CEP170P1	645455	Q96L14	0.72
PPP2R2B	5521	Q00005	0.75
PSMC4	5704	P43686	0.76
ILK	3611	Q13418	0.82
TUBG1	7283	P23258	0.82
TP53	7157	P04637	0.83
STUB1	10273	Q9UNE7	0.85
MLF2	8079	Q15773	0.88
HSPA8	3312	P11142	0.97