BP

GO:0003085

negative regulation of systemic arterial blood pressure

The process that reduces the force with which blood travels through the systemic arterial circulatory system.

IEA

BP

GO:0006813

potassium ion transport

The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

TAS

BP

GO:0030322

stabilization of membrane potential

The accomplishment of a non-fluctuating membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.

IBA

BP

GO:0034765

regulation of ion transmembrane transport

Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.

IEA

BP

GO:0060075

regulation of resting membrane potential

Any process that modulates the establishment or extent of a resting potential, the electrical charge across the plasma membrane, with the interior of the cell negative with respect to the exterior. The resting potential is the membrane potential of a cell that is not stimulated to be depolarized or hyperpolarized.

IEA

BP

GO:0061337

cardiac conduction

Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles.

TAS

BP

GO:0071805

potassium ion transmembrane transport

A process in which a potassium ion is transported from one side of a membrane to the other.

IEA

CC

GO:0005886

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

TAS

CC

GO:0008076

voltage-gated potassium channel complex

A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.

TAS

MF

GO:0005242

inward rectifier potassium channel activity

Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. The inward-rectification is due to a voltage-dependent block of the channel pore by a specific ligand or ligands, and as a result the macroscopic conductance depends on the difference between membrane voltage and the K+ equilibrium potential rather than on membrane voltage itself.

TAS

MF

GO:0005267

potassium channel activity

Enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

TAS

MF

GO:0022841

potassium ion leak channel activity

Enables the transport of a potassium ion across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state.

IBA