| Gene Symbol | CIAO1 |
| Entrez ID | 9391 |
| Uniprot ID | O76071 |
| Description | cytosolic iron-sulfur assembly component 1 |
| Chromosomal Location | chr2: 96,266,132-96,273,349 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0006357 |
regulation of transcription from RNA polymerase II promoter |
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter. |
TAS |
|
BP |
GO:0007059 |
chromosome segregation |
The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles. |
IEA |
|
BP |
GO:0008284 |
positive regulation of cell proliferation |
Any process that activates or increases the rate or extent of cell proliferation. |
TAS |
|
BP |
GO:0016226 |
iron-sulfur cluster assembly |
The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster. |
IGI |
|
CC |
GO:0071817 |
MMXD complex |
A protein complex that contains the proteins MMS19, MIP18 and XPD, localizes to mitotic spindle during mitosis, and is required for proper chromosome segregation. |
IDA |
|
CC |
GO:0097361 |
CIA complex |
The cytosolic iron-sulfur protein assembly (CIA) complex mediates the incorporation of iron-sulfur clusters into apoproteins involved in DNA metabolism and genomic integrity. |
IDA |
|
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
| Domain ID | Description |
|---|---|
|
IPR001680 |
WD40 repeat |
|
IPR015943 |
WD40/YVTN repeat-like-containing domain |
|
IPR017986 |
WD40-repeat-containing domain |
|
IPR019775 |
WD40 repeat, conserved site |
|
IPR028608 |
Probable cytosolic iron-sulfur protein assembly protein, CIAO1/Cia1 |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
appendix |
glandular cells |
|
appendix |
lymphoid tissue |
|
bone marrow |
hematopoietic cells |
|
breast |
glandular cells |
|
bronchus |
respiratory epithelial cells |
|
caudate |
glial cells |
|
caudate |
neuronal cells |
|
cerebellum |
cells in granular layer |
|
cerebellum |
cells in molecular layer |
|
cerebellum |
Purkinje cells |
|
cerebral cortex |
glial cells |
|
cerebral cortex |
neuronal cells |
|
cervix, uterine |
squamous epithelial cells |
|
colon |
endothelial cells |
|
colon |
glandular cells |
|
colon |
peripheral nerve/ganglion |
|
duodenum |
glandular cells |
|
endometrium |
cells in endometrial stroma |
|
epididymis |
glandular cells |
|
esophagus |
squamous epithelial cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
hippocampus |
glial cells |
|
hippocampus |
neuronal cells |
|
kidney |
cells in tubules |
|
lung |
macrophages |
|
lung |
pneumocytes |
|
lymph node |
germinal center cells |
|
lymph node |
non-germinal center cells |
|
nasopharynx |
respiratory epithelial cells |
|
oral mucosa |
squamous epithelial cells |
|
parathyroid gland |
glandular cells |
|
placenta |
decidual cells |
|
placenta |
trophoblastic cells |
|
prostate |
glandular cells |
|
rectum |
glandular cells |
|
seminal vesicle |
glandular cells |
|
skin |
fibroblasts |
|
skin |
epidermal cells |
|
small intestine |
glandular cells |
|
soft tissue |
adipocytes |
|
soft tissue |
chondrocytes |
|
soft tissue |
fibroblasts |
|
spleen |
cells in red pulp |
|
spleen |
cells in white pulp |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
testis |
Leydig cells |
|
thyroid gland |
glandular cells |
|
tonsil |
germinal center cells |
|
tonsil |
non-germinal center cells |
|
tonsil |
squamous epithelial cells |
|
urinary bladder |
urothelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
APP |
351 |
P05067 |
0.56 |
|
ACACA |
31 |
Q13085 |
0.63 |
|
CNP |
1267 |
P09543 |
0.63 |
|
DCTN1 |
1639 |
Q14203 |
0.63 |
|
DNA2 |
1763 |
P51530 |
0.63 |
|
EIF4G2 |
1982 |
P78344 |
0.63 |
|
ERCC2 |
2068 |
P18074 |
0.63 |
|
FBL |
2091 |
P22087 |
0.63 |
|
GOLGA3 |
2802 |
Q08378 |
0.63 |
|
HDAC2 |
3066 |
Q92769 |
0.63 |
|
HELLS |
3070 |
Q9NRZ9 |
0.63 |
|
HSPB1 |
3315 |
P04792 |
0.63 |
|
IREB2 |
3658 |
P48200 |
0.63 |
|
MCM3 |
4172 |
P25205 |
0.63 |
|
MRE11A |
4361 |
P49959 |
0.63 |
|
MYO1B |
4430 |
O43795 |
0.63 |
|
MYO1D |
4642 |
O94832 |
0.63 |
|
NDUFA9 |
4704 |
Q16795 |
0.63 |
|
POLA1 |
5422 |
P09884 |
0.63 |
|
POLD1 |
5424 |
P28340 |
0.63 |
|
POLE |
5426 |
Q07864 |
0.63 |
|
PPAT |
5471 |
Q06203 |
0.63 |
|
PRIM1 |
5557 |
P49642 |
0.63 |
|
PRIM2 |
5558 |
P49643 |
0.63 |
|
PSMB1 |
5689 |
P20618 |
0.63 |
|
HLTF |
6596 |
Q14527 |
0.63 |
|
TROVE2 |
6738 |
P10155 |
0.63 |
|
TSC1 |
7248 |
Q92574 |
0.63 |
|
TSC2 |
7249 |
P49815 |
0.63 |
|
UGDH |
7358 |
O60701 |
0.63 |
|
BAG6 |
7917 |
P46379 |
0.63 |
|
CDC45 |
8318 |
O75419 |
0.63 |
|
DPM1 |
8813 |
O60762 |
0.63 |
|
COPB2 |
9276 |
P35606 |
0.63 |
|
GTF3C5 |
9328 |
Q9Y5Q8 |
0.63 |
|
GTF3C3 |
9330 |
Q9Y5Q9 |
0.63 |
|
POLR1C |
9533 |
O15160 |
0.63 |
|
CHD1L |
9557 |
Q86WJ1 |
0.63 |
|
CTR9 |
9646 |
Q6PD62 |
0.63 |
|
NUP93 |
9688 |
Q8N1F7 |
0.63 |
|
NUBP2 |
10101 |
Q9Y5Y2 |
0.63 |
|
TRIM28 |
10155 |
Q13263 |
0.63 |
|
GLRX3 |
10539 |
O76003 |
0.63 |
|
CLPX |
10845 |
O76031 |
0.63 |
|
ERP29 |
10961 |
P30040 |
0.63 |
|
WDR5 |
11091 |
P61964 |
0.63 |
|
KATNA1 |
11104 |
O75449 |
0.63 |
|
DDX20 |
11218 |
Q9UHI6 |
0.63 |
|
SNRNP200 |
23020 |
O75643 |
0.63 |
|
WDR43 |
23160 |
Q15061 |
0.63 |
|
ELP5 |
23587 |
Q8TE02 |
0.63 |
|
POLA2 |
23649 |
Q14181 |
0.63 |
|
RPAP1 |
26015 |
Q9BWH6 |
0.63 |
|
GNL3 |
26354 |
Q9BVP2 |
0.63 |
|
ELP4 |
26610 |
Q96EB1 |
0.63 |
|
AKAP8L |
26993 |
Q9ULX6 |
0.63 |
|
TUBG2 |
27175 |
Q9NRH3 |
0.63 |
|
GOLM1 |
51280 |
Q8NBJ4 |
0.63 |
|
RTEL1 |
51750 |
Q9NZ71 |
0.63 |
|
PHAX |
51808 |
Q9H814 |
0.63 |
|
PLEKHA5 |
54477 |
Q9HAU0 |
0.63 |
|
PAF1 |
54623 |
Q8N7H5 |
0.63 |
|
ELP6 |
54859 |
Q0PNE2 |
0.63 |
|
DPP8 |
54878 |
Q6V1X1 |
0.63 |
|
CDKAL1 |
54901 |
Q5VV42 |
0.63 |
|
UCKL1 |
54963 |
Q9NWZ5 |
0.63 |
|
ELP3 |
55140 |
Q9H9T3 |
0.63 |
|
ELP2 |
55250 |
Q6IA86 |
0.63 |
|
TYW1 |
55253 |
Q9NV66 |
0.63 |
|
YAE1D1 |
57002 |
Q9NRH1 |
0.63 |
|
UPF3B |
65109 |
Q9BZI7 |
0.63 |
|
CDC73 |
79577 |
Q6P1J9 |
0.63 |
|
MRPL24 |
79590 |
Q96A35 |
0.63 |
|
IPO4 |
79711 |
Q8TEX9 |
0.63 |
|
WDR61 |
80349 |
Q9GZS3 |
0.63 |
|
EEPD1 |
80820 |
Q7L9B9 |
0.63 |
|
NSRP1 |
84081 |
Q9H0G5 |
0.63 |
|
WDR75 |
84128 |
Q8IWA0 |
0.63 |
|
MAK16 |
84549 |
Q9BXY0 |
0.63 |
|
PPIL4 |
85313 |
Q8WUA2 |
0.63 |
|
CTU1 |
90353 |
Q7Z7A3 |
0.63 |
|
FMNL3 |
91010 |
Q8IVF7 |
0.63 |
|
DPP9 |
91039 |
Q86TI2 |
0.63 |
|
SLFN11 |
91607 |
Q7Z7L1 |
0.63 |
|
TOE1 |
114034 |
Q96GM8 |
0.63 |
|
FMNL2 |
114793 |
Q96PY5 |
0.63 |
|
LEO1 |
123169 |
Q8WVC0 |
0.63 |
|
NUP35 |
129401 |
Q8NFH5 |
0.63 |
|
CTU2 |
348180 |
Q2VPK5 |
0.63 |
|
ABCE1 |
6059 |
P61221 |
0.73 |
|
MCM5 |
4174 |
P33992 |
0.76 |
|
MYO1C |
4641 |
O00159 |
0.76 |
|
WT1 |
7490 |
P19544 |
0.76 |
|
USP11 |
8237 |
P51784 |
0.76 |
|
DNAAF5 |
54919 |
Q86Y56 |
0.76 |
|
CCAR2 |
57805 |
Q8N163 |
0.76 |
|
NARFL |
64428 |
Q9H6Q4 |
0.79 |
|
SF1 |
7536 |
Q15637 |
0.82 |
|
FAM96B |
51647 |
Q9Y3D0 |
0.83 |
|
MMS19 |
64210 |
Q96T76 |
0.94 |
|
CCDC7 |
79741 |
Q96M83 |
0.63 |
|
MPPED1 |
758 |
O15442 |
0.63 |
|
MEOX1 |
4222 |
P50221 |
0.63 |
|
NEDD8 |
4738 |
Q15843 |
0.63 |
|
SLC30A4 |
7782 |
O14863 |
0.63 |
|
CDK2AP1 |
8099 |
O14519 |
0.63 |
|
WBP1 |
23559 |
Q96G27 |
0.63 |
|
RSAD2 |
91543 |
Q8WXG1 |
0.63 |
|
SRPK1 |
6732 |
Q96SB4 |
0.70 |
|
GAS8 |
2622 |
O95995 |
0.76 |
|
MLF2 |
8079 |
Q15773 |
0.76 |
|
FAM96A |
84191 |
Q9H5X1 |
0.83 |