Gene Symbol | B4GALT6 |
Entrez ID | 9331 |
Uniprot ID | Q9UBX8 |
Description | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 |
Chromosomal Location | chr18: 31,622,247-31,685,836 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006486 |
protein glycosylation |
A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins. |
IEA |
BP |
GO:0018146 |
keratan sulfate biosynthetic process |
The chemical reactions and pathways resulting in the formation of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues. |
TAS |
CC |
GO:0000139 |
Golgi membrane |
The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
TAS |
CC |
GO:0016021 |
integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IEA |
CC |
GO:0032580 |
Golgi cisterna membrane |
The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex. |
IEA |
MF |
GO:0003831 |
beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity |
Catalysis of the reaction: UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide = UDP + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminylglycopeptide. |
TAS |
MF |
GO:0008378 |
galactosyltransferase activity |
Catalysis of the transfer of a galactosyl group to an acceptor molecule, typically another carbohydrate or a lipid. |
TAS |
MF |
GO:0046872 |
metal ion binding |
Interacting selectively and non-covalently with any metal ion. |
IEA |
Domain ID | Description |
---|---|
IPR003859 |
Beta-1,4-galactosyltransferase |
IPR027791 |
Galactosyltransferase, C-terminal |
IPR027995 |
Galactosyltransferase, N-terminal |
IPR029044 |
Nucleotide-diphospho-sugar transferases |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa00600 |
Sphingolipid metabolism |
KEGG |
hsa01100 |
Metabolic pathways |
KEGG |
WP1422 |
Sphingolipid Metabolism |
WikiPathways |
UMLS CUI | UMLS Term |
---|---|
C0002736 |
Amyotrophic Lateral Sclerosis |
Tissue | Cell Type |
---|---|
cerebral cortex |
glial cells |
duodenum |
glandular cells |
small intestine |
glandular cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
15308691 |
Jansen et al. |
2004 |
Abnormal Gene Expression Profiles in Human Ovaries from Polycystic Ovary Syndrome Patients |