Protein Description

Gene Symbol B4GALT6
Entrez ID 9331
Uniprot ID Q9UBX8
Description UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
Chromosomal Location chr18: 31,622,247-31,685,836
Ontology GO ID GO Term Definition Evidence

BP

GO:0006486

protein glycosylation

A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.

IEA

BP

GO:0018146

keratan sulfate biosynthetic process

The chemical reactions and pathways resulting in the formation of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.

TAS

CC

GO:0000139

Golgi membrane

The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

TAS

CC

GO:0016021

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

IEA

CC

GO:0032580

Golgi cisterna membrane

The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex.

IEA

MF

GO:0003831

beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity

Catalysis of the reaction: UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide = UDP + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminylglycopeptide.

TAS

MF

GO:0008378

galactosyltransferase activity

Catalysis of the transfer of a galactosyl group to an acceptor molecule, typically another carbohydrate or a lipid.

TAS

MF

GO:0046872

metal ion binding

Interacting selectively and non-covalently with any metal ion.

IEA

Domain ID Description

IPR003859

Beta-1,4-galactosyltransferase

IPR027791

Galactosyltransferase, C-terminal

IPR027995

Galactosyltransferase, N-terminal

IPR029044

Nucleotide-diphospho-sugar transferases

Pathway ID Pathway Term Pathway Source

hsa00600

Sphingolipid metabolism

KEGG

hsa01100

Metabolic pathways

KEGG

WP1422

Sphingolipid Metabolism

WikiPathways

UMLS CUI UMLS Term

C0002736

Amyotrophic Lateral Sclerosis

Tissue Cell Type

cerebral cortex

glial cells

duodenum

glandular cells

small intestine

glandular cells

No databases found.

Pubmed ID Author Year Title

15308691

Jansen et al.

2004

Abnormal Gene Expression Profiles in Human Ovaries from Polycystic Ovary Syndrome Patients

No partners found.