Protein Description

Gene Symbol CD83
Entrez ID 9308
Uniprot ID Q01151
Description CD83 molecule
Chromosomal Location chr6: 14,117,256-14,136,918
Ontology GO ID GO Term Definition Evidence

BP

GO:0001817

regulation of cytokine production

Any process that modulates the frequency, rate, or extent of production of a cytokine.

IBA

BP

GO:0006952

defense response

Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

TAS

BP

GO:0006959

humoral immune response

An immune response mediated through a body fluid.

TAS

BP

GO:0007165

signal transduction

The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.

TAS

BP

GO:0014070

response to organic cyclic compound

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.

IEA

BP

GO:0032713

negative regulation of interleukin-4 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-4 production.

IEA

BP

GO:0032733

positive regulation of interleukin-10 production

Any process that activates or increases the frequency, rate, or extent of interleukin-10 production.

IEA

BP

GO:0032743

positive regulation of interleukin-2 production

Any process that activates or increases the frequency, rate, or extent of interleukin-2 production.

IEA

BP

GO:0043372

positive regulation of CD4-positive, alpha-beta T cell differentiation

Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell differentiation.

IEA

CC

GO:0005886

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

TAS

CC

GO:0005887

integral component of plasma membrane

The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

TAS

CC

GO:0009897

external side of plasma membrane

The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.

IEA

Domain ID Description

IPR003599

Immunoglobulin subtype

IPR007110

Immunoglobulin-like domain

IPR013106

Immunoglobulin V-set domain

IPR013783

Immunoglobulin-like fold

Pathway ID Pathway Term Pathway Source

WP69

T-Cell antigen Receptor (TCR) Signaling Pathway

WikiPathways

UMLS CUI UMLS Term

C0003873

Rheumatoid Arthritis

C0037274

Dermatologic Disorders

C0311375

Arsenic Poisoning

C3495559

Juvenile Arthritis

No tissues found.

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

23824412

Piltonen et al.

2013

Mesenchymal Stem/Progenitors and Other Endometrial Cell Types From Women With Polycystic Ovary Syndrome (PCOS) Display Inflammatory and Oncogenic Potential

Gene Symbol Entrez ID Uniprot ID Score

EIF4E

1977

P06730

0.63