| Gene Symbol | SRSF11 |
| Entrez ID | 9295 |
| Uniprot ID | Q05519 |
| Description | serine/arginine-rich splicing factor 11 |
| Chromosomal Location | chr1: 70,205,682-70,253,052 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0000398 |
mRNA splicing, via spliceosome |
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced. |
TAS |
|
BP |
GO:0006369 |
termination of RNA polymerase II transcription |
The process in which the synthesis of an RNA molecule by RNA polymerase II using a DNA template is completed. |
TAS |
|
BP |
GO:0006397 |
mRNA processing |
Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. |
TAS |
|
BP |
GO:0006405 |
RNA export from nucleus |
The directed movement of RNA from the nucleus to the cytoplasm. |
TAS |
|
BP |
GO:0006406 |
mRNA export from nucleus |
The directed movement of mRNA from the nucleus to the cytoplasm. |
TAS |
|
BP |
GO:0008380 |
RNA splicing |
The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. |
TAS |
|
BP |
GO:0031124 |
mRNA 3'-end processing |
Any process involved in forming the mature 3' end of an mRNA molecule. |
TAS |
|
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
TAS |
|
CC |
GO:0005654 |
nucleoplasm |
That part of the nuclear content other than the chromosomes or the nucleolus. |
IDA|TAS |
|
MF |
GO:0000166 |
nucleotide binding |
Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. |
IEA |
|
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
|
MF |
GO:0044822 |
poly(A) RNA binding |
Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases. |
IDA |
| Domain ID | Description |
|---|---|
|
IPR000504 |
RNA recognition motif domain |
|
IPR034447 |
Serine/arginine-rich splicing factor 11 |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
appendix |
glandular cells |
|
appendix |
lymphoid tissue |
|
bone marrow |
hematopoietic cells |
|
breast |
glandular cells |
|
breast |
myoepithelial cells |
|
bronchus |
respiratory epithelial cells |
|
caudate |
glial cells |
|
caudate |
neuronal cells |
|
cerebellum |
cells in granular layer |
|
cerebellum |
cells in molecular layer |
|
cerebellum |
Purkinje cells |
|
cerebral cortex |
endothelial cells |
|
cerebral cortex |
glial cells |
|
cerebral cortex |
neuronal cells |
|
cervix, uterine |
squamous epithelial cells |
|
colon |
endothelial cells |
|
colon |
glandular cells |
|
duodenum |
glandular cells |
|
endometrium |
cells in endometrial stroma |
|
endometrium |
glandular cells |
|
epididymis |
glandular cells |
|
esophagus |
squamous epithelial cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
heart muscle |
myocytes |
|
hippocampus |
glial cells |
|
hippocampus |
neuronal cells |
|
lung |
macrophages |
|
lung |
pneumocytes |
|
lymph node |
germinal center cells |
|
lymph node |
non-germinal center cells |
|
nasopharynx |
respiratory epithelial cells |
|
oral mucosa |
squamous epithelial cells |
|
ovary |
ovarian stroma cells |
|
pancreas |
exocrine glandular cells |
|
pancreas |
islets of Langerhans |
|
parathyroid gland |
glandular cells |
|
placenta |
decidual cells |
|
placenta |
trophoblastic cells |
|
prostate |
glandular cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
seminal vesicle |
glandular cells |
|
skeletal muscle |
myocytes |
|
skin |
keratinocytes |
|
skin |
Langerhans |
|
skin |
melanocytes |
|
skin |
epidermal cells |
|
small intestine |
glandular cells |
|
smooth muscle |
smooth muscle cells |
|
spleen |
cells in red pulp |
|
spleen |
cells in white pulp |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
testis |
Leydig cells |
|
thyroid gland |
glandular cells |
|
tonsil |
germinal center cells |
|
tonsil |
non-germinal center cells |
|
tonsil |
squamous epithelial cells |
|
urinary bladder |
urothelial cells |
|
vagina |
squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
15291743 |
Diao et al. |
2004 |
The molecular characteristics of polycystic ovary syndrome (PCOS) ovary defined by human ovary cDNA microarray |
|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
EEF1A1 |
1915 |
P68104 |
0.49 |
|
SRSF3 |
6428 |
P84103 |
0.49 |
|
SRSF7 |
6432 |
Q16629 |
0.49 |
|
SNRPA |
6626 |
P09012 |
0.49 |
|
SON |
6651 |
P18583 |
0.49 |
|
TFPI |
7035 |
P10646 |
0.49 |
|
TPBG |
7162 |
Q13641 |
0.49 |
|
VTN |
7448 |
P04004 |
0.49 |
|
RUVBL1 |
8607 |
Q9Y265 |
0.49 |
|
SRSF9 |
8683 |
Q13242 |
0.49 |
|
SART1 |
9092 |
O43290 |
0.49 |
|
ZNF592 |
9640 |
Q92610 |
0.49 |
|
TOX4 |
9878 |
O94842 |
0.49 |
|
THRAP3 |
9967 |
Q9Y2W1 |
0.49 |
|
HEXIM1 |
10614 |
O94992 |
0.49 |
|
USP39 |
10713 |
Q53GS9 |
0.49 |
|
UTP14A |
10813 |
Q9BVJ6 |
0.49 |
|
TCERG1 |
10915 |
O14776 |
0.49 |
|
SF3B2 |
10992 |
Q13435 |
0.49 |
|
SRRM2 |
23524 |
Q9UQ35 |
0.49 |
|
PNISR |
25957 |
Q8TF01 |
0.49 |
|
TRMT112 |
51504 |
Q9UI30 |
0.49 |
|
LUC7L2 |
51631 |
Q9Y383 |
0.49 |
|
ARGLU1 |
55082 |
Q9NWB6 |
0.49 |
|
SMU1 |
55234 |
Q2TAY7 |
0.49 |
|
RBM25 |
58517 |
P49756 |
0.49 |
|
SHCBP1 |
79801 |
Q8NEM2 |
0.49 |
|
AGMAT |
79814 |
Q9BSE5 |
0.49 |
|
TRIM55 |
84675 |
Q9BYV6 |
0.49 |
|
VASN |
114990 |
Q6EMK4 |
0.49 |
|
DDOST |
1650 |
P39656 |
0.63 |
|
SRSF1 |
6426 |
Q07955 |
0.63 |
|
SRSF2 |
6427 |
Q01130 |
0.63 |
|
TANK |
10010 |
Q92844 |
0.63 |
|
ARL6IP4 |
51329 |
Q66PJ3 |
0.63 |
|
HYI |
81888 |
Q5T013 |
0.63 |
|
SREK1 |
140890 |
Q8WXA9 |
0.63 |
|
U2AF2 |
11338 |
P26368 |
0.68 |
|
CDK6 |
1021 |
Q00534 |
0.70 |
|
CSNK2A1 |
1457 |
P68400 |
0.70 |
|
ETS1 |
2113 |
P14921 |
0.73 |
|
RBM39 |
9584 |
Q14498 |
0.73 |
|
DHX15 |
1665 |
O43143 |
0.49 |
|
EWSR1 |
2130 |
Q01844 |
0.49 |
|
FLNA |
2316 |
P21333 |
0.49 |
|
HNRNPK |
3190 |
P61978 |
0.49 |
|
HNRNPU |
3192 |
Q00839 |
0.49 |
|
IK |
3550 |
Q13123 |
0.49 |
|
SMAD2 |
4087 |
Q15796 |
0.49 |
|
MSH2 |
4436 |
P43246 |
0.49 |
|
SNU13 |
4809 |
P55769 |
0.49 |
|
PPP1CA |
5499 |
P62136 |
0.49 |
|
S100A9 |
6280 |
P06702 |
0.49 |
|
SNRNP70 |
6625 |
P08621 |
0.49 |
|
TPR |
7175 |
P12270 |
0.49 |
|
SAP18 |
10284 |
O00422 |
0.49 |
|
RBM14 |
10432 |
Q96PK6 |
0.49 |
|
NCSTN |
23385 |
Q92542 |
0.49 |
|
PHGDH |
26227 |
O43175 |
0.49 |
|
PRPF19 |
27339 |
Q9UMS4 |
0.49 |
|
SF3B6 |
51639 |
Q9Y3B4 |
0.49 |
|
SRPK2 |
6733 |
P78362 |
0.52 |
|
DDX46 |
9879 |
Q7L014 |
0.59 |
|
JUN |
3725 |
P05412 |
0.63 |
|
MDM2 |
4193 |
Q00987 |
0.63 |
|
NTRK1 |
4914 |
P04629 |
0.63 |
|
SDCBP |
6386 |
O00560 |
0.63 |
|
TERF2 |
7014 |
Q15554 |
0.63 |
|
VCP |
7415 |
P55072 |
0.63 |
|
YWHAG |
7532 |
P61981 |
0.63 |
|
CUL3 |
8452 |
Q13618 |
0.63 |
|
ZRANB2 |
9406 |
O95218 |
0.63 |
|
KIAA0101 |
9768 |
Q15004 |
0.63 |
|
GABARAPL2 |
11345 |
P60520 |
0.63 |
|
SNW1 |
22938 |
Q13573 |
0.63 |
|
OBSL1 |
23363 |
O75147 |
0.63 |
|
LUC7L |
55692 |
Q9NQ29 |
0.63 |
|
CAND1 |
55832 |
Q86VP6 |
0.63 |
|
THAP11 |
57215 |
Q96EK4 |
0.63 |
|
LNX2 |
222484 |
Q8N448 |
0.63 |
|
PIN1 |
5300 |
Q13526 |
0.68 |
|
MME |
4311 |
P08473 |
0.72 |
|
TOP1 |
7150 |
P11387 |
0.73 |
|
RNPS1 |
10921 |
Q15287 |
0.86 |
|
PUF60 |
22827 |
Q9UHX1 |
0.89 |
|
GATC |
283459 |
O43716 |
0.49 |