BP

GO:0032012

regulation of ARF protein signal transduction

Any process that modulates the frequency, rate or extent of ARF protein signal transduction.

IEA

BP

GO:0043547

positive regulation of GTPase activity

Any process that activates or increases the activity of a GTPase.

IEA

BP

GO:0045785

positive regulation of cell adhesion

Any process that activates or increases the frequency, rate or extent of cell adhesion.

IEA

BP

GO:0048193

Golgi vesicle transport

The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.

IMP

BP

GO:0090162

establishment of epithelial cell polarity

The specification and formation of anisotropic intracellular organization of an epithelial cell.

IEA

CC

GO:0000139

Golgi membrane

The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

TAS

CC

GO:0001726

ruffle

Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork.

IEA

CC

GO:0005829

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

IDA|TAS

CC

GO:0005886

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

IDA

CC

GO:0031234

extrinsic component of cytoplasmic side of plasma membrane

The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its cytoplasmic surface, but not integrated into the hydrophobic region.

IDA

MF

GO:0005086

ARF guanyl-nucleotide exchange factor activity

Stimulates the exchange of guanyl nucleotides associated with the GTPase ARF. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.

IDA

MF

GO:0005547

phosphatidylinositol-3,4,5-trisphosphate binding

Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.

IDA