Gene Symbol | SLC33A1 |
Entrez ID | 9197 |
Uniprot ID | O00400 |
Description | solute carrier family 33 (acetyl-CoA transporter), member 1 |
Chromosomal Location | chr3: 155,821,024-155,854,429 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006810 |
transport |
The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein. |
TAS |
BP |
GO:0015876 |
acetyl-CoA transport |
The directed movement of acetyl-CoA into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis. |
IEA |
BP |
GO:0015992 |
proton transport |
The directed movement of protons (hydrogen ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
IEA |
BP |
GO:0030509 |
BMP signaling pathway |
A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. |
IDA |
BP |
GO:0055085 |
transmembrane transport |
The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other |
TAS |
BP |
GO:0060395 |
SMAD protein signal transduction |
The cascade of processes by which a signal interacts with a receptor, causing a change in the activity of a SMAD protein, and ultimately effecting a change in the functioning of the cell. |
IDA |
CC |
GO:0000139 |
Golgi membrane |
The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
TAS |
CC |
GO:0005789 |
endoplasmic reticulum membrane |
The lipid bilayer surrounding the endoplasmic reticulum. |
IEA |
CC |
GO:0005887 |
integral component of plasma membrane |
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
TAS |
CC |
GO:0016020 |
membrane |
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
IDA |
MF |
GO:0008521 |
acetyl-CoA transporter activity |
Enables the directed movement of acetyl-CoA into, out of or within a cell, or between cells. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis. |
TAS |
MF |
GO:0015295 |
solute:proton symporter activity |
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(out) = solute(in) + H+(in). |
IBA |
Domain ID | Description |
---|---|
IPR004752 |
AmpG-like permease/Acetyl-coenzyme A transporter 1 |
IPR020846 |
Major facilitator superfamily domain |
IPR024371 |
Acetyl-coenzyme A transporter 1 |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa00604 |
Glycosphingolipid biosynthesis - ganglio series |
KEGG |
hsa01100 |
Metabolic pathways |
KEGG |
WP1423 |
Ganglio Sphingolipid Metabolism |
WikiPathways |
UMLS CUI | UMLS Term |
---|---|
C0008073 |
Developmental Disabilities |
C0086543 |
Cataract |
C1384666 |
Hearing Impairment |
Tissue | Cell Type |
---|---|
cerebral cortex |
neuronal cells |
duodenum |
glandular cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
ATP5E |
514 |
P56381 |
0.63 |
MT-ATP6 |
4508 |
P00846 |
0.63 |
MT-ATP8 |
4509 |
P03928 |
0.63 |
MCAT |
27349 |
Q8IVS2 |
0.63 |
METTL8 |
79828 |
Q9H825 |
0.63 |
MSL1 |
339287 |
Q68DK7 |
0.63 |
ATP5EP2 |
432369 |
Q5VTU8 |
0.63 |
ATP2A2 |
488 |
P16615 |
0.72 |
ATP5A1 |
498 |
P25705 |
0.72 |
ATP5O |
539 |
P48047 |
0.72 |
CANX |
821 |
P27824 |
0.72 |
CLCN7 |
1186 |
P51798 |
0.72 |
CLIC1 |
1192 |
O00299 |
0.72 |
EEF1D |
1936 |
P29692 |
0.72 |
EEF1G |
1937 |
P26641 |
0.72 |
MAT2A |
4144 |
P31153 |
0.72 |
MKI67 |
4288 |
P46013 |
0.72 |
MST1R |
4486 |
Q04912 |
0.72 |
MYO1E |
4643 |
Q12965 |
0.72 |
NF2 |
4771 |
P35240 |
0.72 |
PFN1 |
5216 |
P07737 |
0.72 |
RAD51 |
5888 |
Q06609 |
0.72 |
SLC7A1 |
6541 |
P30825 |
0.72 |
TAP1 |
6890 |
Q03518 |
0.72 |
TCEB2 |
6923 |
Q15370 |
0.72 |
TPM4 |
7171 |
P67936 |
0.72 |
HSP90B1 |
7184 |
P14625 |
0.72 |
SEMA3B |
7869 |
Q13214 |
0.72 |
TAGLN2 |
8407 |
P37802 |
0.72 |
ARHGEF7 |
8874 |
Q14155 |
0.72 |
ZW10 |
9183 |
O43264 |
0.72 |
SNUPN |
10073 |
O95149 |
0.72 |
RAD50 |
10111 |
Q92878 |
0.72 |
INADL |
10207 |
Q8NI35 |
0.72 |
CEPT1 |
10390 |
Q9Y6K0 |
0.72 |
HAX1 |
10456 |
O00165 |
0.72 |
CKAP4 |
10970 |
Q07065 |
0.72 |
IMMT |
10989 |
Q16891 |
0.72 |
SLC27A2 |
11001 |
O14975 |
0.72 |
USP24 |
23358 |
Q9UPU5 |
0.72 |
ECM29 |
23392 |
Q5VYK3 |
0.72 |
PHGDH |
26227 |
O43175 |
0.72 |
CKAP2 |
26586 |
Q8WWK9 |
0.72 |
GIT1 |
28964 |
Q9Y2X7 |
0.72 |
RAB14 |
51552 |
P61106 |
0.72 |
TMEM57 |
55219 |
Q8N5G2 |
0.72 |
NCLN |
56926 |
Q969V3 |
0.72 |
DOCK6 |
57572 |
Q96HP0 |
0.72 |
|
64146 |
Q9HBH1 |
0.72 |
C19orf43 |
79002 |
Q9BQ61 |
0.72 |
ELMO3 |
79767 |
Q96BJ8 |
0.72 |
NUDT18 |
79873 |
Q6ZVK8 |
0.72 |
ZNF598 |
90850 |
Q86UK7 |
0.72 |
HSP90AB1 |
3326 |
P08238 |
0.79 |
TCTN3 |
26123 |
Q6NUS6 |
0.49 |
TMEM216 |
51259 |
Q9P0N5 |
0.49 |
TCTN2 |
79867 |
Q96GX1 |
0.49 |
EVC2 |
132884 |
Q86UK5 |
0.49 |
TMEM17 |
200728 |
Q86X19 |
0.49 |
JUN |
3725 |
P05412 |
0.63 |
UBD |
10537 |
O15205 |
0.63 |