Protein Description

Gene Symbol SLC33A1
Entrez ID 9197
Uniprot ID O00400
Description solute carrier family 33 (acetyl-CoA transporter), member 1
Chromosomal Location chr3: 155,821,024-155,854,429
Ontology GO ID GO Term Definition Evidence

BP

GO:0006810

transport

The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein.

TAS

BP

GO:0015876

acetyl-CoA transport

The directed movement of acetyl-CoA into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.

IEA

BP

GO:0015992

proton transport

The directed movement of protons (hydrogen ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

IEA

BP

GO:0030509

BMP signaling pathway

A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.

IDA

BP

GO:0055085

transmembrane transport

The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other

TAS

BP

GO:0060395

SMAD protein signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the activity of a SMAD protein, and ultimately effecting a change in the functioning of the cell.

IDA

CC

GO:0000139

Golgi membrane

The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

TAS

CC

GO:0005789

endoplasmic reticulum membrane

The lipid bilayer surrounding the endoplasmic reticulum.

IEA

CC

GO:0005887

integral component of plasma membrane

The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

TAS

CC

GO:0016020

membrane

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

IDA

MF

GO:0008521

acetyl-CoA transporter activity

Enables the directed movement of acetyl-CoA into, out of or within a cell, or between cells. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.

TAS

MF

GO:0015295

solute:proton symporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(out) = solute(in) + H+(in).

IBA

Domain ID Description

IPR004752

AmpG-like permease/Acetyl-coenzyme A transporter 1

IPR020846

Major facilitator superfamily domain

IPR024371

Acetyl-coenzyme A transporter 1

Pathway ID Pathway Term Pathway Source

hsa00604

Glycosphingolipid biosynthesis - ganglio series

KEGG

hsa01100

Metabolic pathways

KEGG

WP1423

Ganglio Sphingolipid Metabolism

WikiPathways

UMLS CUI UMLS Term

C0008073

Developmental Disabilities

C0086543

Cataract

C1384666

Hearing Impairment

Tissue Cell Type

cerebral cortex

neuronal cells

duodenum

glandular cells

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol Entrez ID Uniprot ID Score

ATP5E

514

P56381

0.63

MT-ATP6

4508

P00846

0.63

MT-ATP8

4509

P03928

0.63

MCAT

27349

Q8IVS2

0.63

METTL8

79828

Q9H825

0.63

MSL1

339287

Q68DK7

0.63

ATP5EP2

432369

Q5VTU8

0.63

ATP2A2

488

P16615

0.72

ATP5A1

498

P25705

0.72

ATP5O

539

P48047

0.72

CANX

821

P27824

0.72

CLCN7

1186

P51798

0.72

CLIC1

1192

O00299

0.72

EEF1D

1936

P29692

0.72

EEF1G

1937

P26641

0.72

MAT2A

4144

P31153

0.72

MKI67

4288

P46013

0.72

MST1R

4486

Q04912

0.72

MYO1E

4643

Q12965

0.72

NF2

4771

P35240

0.72

PFN1

5216

P07737

0.72

RAD51

5888

Q06609

0.72

SLC7A1

6541

P30825

0.72

TAP1

6890

Q03518

0.72

TCEB2

6923

Q15370

0.72

TPM4

7171

P67936

0.72

HSP90B1

7184

P14625

0.72

SEMA3B

7869

Q13214

0.72

TAGLN2

8407

P37802

0.72

ARHGEF7

8874

Q14155

0.72

ZW10

9183

O43264

0.72

SNUPN

10073

O95149

0.72

RAD50

10111

Q92878

0.72

INADL

10207

Q8NI35

0.72

CEPT1

10390

Q9Y6K0

0.72

HAX1

10456

O00165

0.72

CKAP4

10970

Q07065

0.72

IMMT

10989

Q16891

0.72

SLC27A2

11001

O14975

0.72

USP24

23358

Q9UPU5

0.72

ECM29

23392

Q5VYK3

0.72

PHGDH

26227

O43175

0.72

CKAP2

26586

Q8WWK9

0.72

GIT1

28964

Q9Y2X7

0.72

RAB14

51552

P61106

0.72

TMEM57

55219

Q8N5G2

0.72

NCLN

56926

Q969V3

0.72

DOCK6

57572

Q96HP0

0.72

PDF

64146

Q9HBH1

0.72

C19orf43

79002

Q9BQ61

0.72

ELMO3

79767

Q96BJ8

0.72

NUDT18

79873

Q6ZVK8

0.72

ZNF598

90850

Q86UK7

0.72

HSP90AB1

3326

P08238

0.79

TCTN3

26123

Q6NUS6

0.49

TMEM216

51259

Q9P0N5

0.49

TCTN2

79867

Q96GX1

0.49

EVC2

132884

Q86UK5

0.49

TMEM17

200728

Q86X19

0.49

JUN

3725

P05412

0.63

UBD

10537

O15205

0.63