Protein Description

Gene Symbol FUBP1
Entrez ID 8880
Uniprot ID Q96AE4
Description far upstream element (FUSE) binding protein 1
Chromosomal Location chr1: 77,944,055-77,979,110
Ontology GO ID GO Term Definition Evidence

BP

GO:0006355

regulation of transcription, DNA-templated

Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

IEA

BP

GO:0006366

transcription from RNA polymerase II promoter

The synthesis of RNA from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).

TAS

BP

GO:0010628

positive regulation of gene expression

Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.

IDA

CC

GO:0005634

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

IDA

CC

GO:0005654

nucleoplasm

That part of the nuclear content other than the chromosomes or the nucleolus.

IDA

MF

GO:0003697

single-stranded DNA binding

Interacting selectively and non-covalently with single-stranded DNA.

TAS

MF

GO:0003700

transcription factor activity, sequence-specific DNA binding

Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.

TAS

MF

GO:0044822

poly(A) RNA binding

Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases.

IDA

Domain ID Description

IPR004087

K Homology domain

IPR004088

K Homology domain, type 1

IPR015096

Far upstream element-binding protein, C-terminal

No pathways found.

No diseases found.

Tissue Cell Type

adrenal gland

glandular cells

appendix

glandular cells

appendix

lymphoid tissue

bone marrow

hematopoietic cells

breast

glandular cells

breast

myoepithelial cells

bronchus

respiratory epithelial cells

caudate

glial cells

caudate

neuronal cells

cerebellum

cells in molecular layer

cerebral cortex

glial cells

cerebral cortex

neuronal cells

cervix, uterine

glandular cells

cervix, uterine

squamous epithelial cells

colon

endothelial cells

colon

glandular cells

colon

peripheral nerve/ganglion

duodenum

glandular cells

endometrium

cells in endometrial stroma

endometrium

glandular cells

epididymis

glandular cells

esophagus

squamous epithelial cells

fallopian tube

glandular cells

gallbladder

glandular cells

heart muscle

myocytes

hippocampus

glial cells

hippocampus

neuronal cells

kidney

cells in glomeruli

kidney

cells in tubules

liver

bile duct cells

liver

hepatocytes

lung

macrophages

lung

pneumocytes

lymph node

germinal center cells

lymph node

non-germinal center cells

nasopharynx

respiratory epithelial cells

oral mucosa

squamous epithelial cells

ovary

ovarian stroma cells

pancreas

exocrine glandular cells

pancreas

islets of Langerhans

parathyroid gland

glandular cells

placenta

decidual cells

placenta

trophoblastic cells

prostate

glandular cells

rectum

glandular cells

salivary gland

glandular cells

seminal vesicle

glandular cells

skeletal muscle

myocytes

skin

fibroblasts

skin

keratinocytes

skin

melanocytes

skin

epidermal cells

small intestine

glandular cells

smooth muscle

smooth muscle cells

soft tissue

adipocytes

soft tissue

fibroblasts

soft tissue

peripheral nerve

spleen

cells in red pulp

spleen

cells in white pulp

stomach

glandular cells

testis

cells in seminiferous ducts

thyroid gland

glandular cells

tonsil

germinal center cells

tonsil

non-germinal center cells

tonsil

squamous epithelial cells

urinary bladder

urothelial cells

vagina

squamous epithelial cells

No databases found.

Pubmed ID Author Year Title

17557764

Ma et al.

2007

Proteomic analysis of human ovaries from normal and polycystic ovarian syndrome

Gene Symbol Entrez ID Uniprot ID Score

KAT2A

2648

Q92830

0.14

ANXA2

302

P07355

0.49

ANXA11

311

P50995

0.49

DUT

1854

P33316

0.49

ITGA5

3678

P08648

0.49

NDUFS4

4724

O43181

0.49

NME1

4830

P15531

0.49

PCBP2

5094

Q15366

0.49

PGM1

5236

P36871

0.49

PKM

5315

P14618

0.49

PPIC

5480

P45877

0.49

RAB1A

5861

P62820

0.49

RPS15

6209

P62841

0.49

SRSF3

6428

P84103

0.49

SMARCC1

6599

Q92922

0.49

SMARCC2

6601

Q8TAQ2

0.49

PRDX2

7001

P32119

0.49

FUBP3

8939

Q96I24

0.49

PDCD6

10016

O75340

0.49

PRDX5

25824

P30044

0.49

SIN3A

25942

Q96ST3

0.49

MRPL46

26589

Q9H2W6

0.49

CHORDC1

26973

Q9UHD1

0.49

MRPL42

28977

Q9Y6G3

0.49

CERS2

29956

Q96G23

0.49

MRPL2

51069

Q5T653

0.49

MRPL41

64975

Q8IXM3

0.49

MRPL38

64978

Q96DV4

0.49

MRPL32

64983

Q9BYC8

0.49

CCDC58

131076

Q4VC31

0.49

PCBP1

5093

Q15365

0.59

IMMT

10989

Q16891

0.62

ACO1

48

P21399

0.63

CNN2

1265

Q99439

0.63

LGALS1

3956

P09382

0.63

PARK2

5071

O60260

0.63

PPP5C

5536

P53041

0.63

HIST1H2BO

8348

P23527

0.63

CELF1

10658

Q92879

0.63

PLD3

23646

Q8IV08

0.63

DDX19A

55308

Q9NUU7

0.63

GRPEL1

80273

Q9HAV7

0.63

CCNH

902

P51946

0.73

GTF2H1

2965

P32780

0.74

USP22

23326

Q9UPT9

0.76

SMN1; SMN2

6606

Q16637

0.89

AIMP2

7965

Q13155

0.90

ARF4

378

P18085

0.49

ATP1B1

481

P05026

0.49

CAPG

822

P40121

0.49

CRIP1

1396

P50238

0.49

CRK

1398

P46108

0.49

SMARCA2

6595

P51531

0.49

FSCN1

6624

Q16658

0.49

SPR

6697

P35270

0.49

PIR

8544

O00625

0.49

KYNU

8942

Q16719

0.49

RACK1

10399

P63244

0.49

TOMM40

10452

O96008

0.49

LAP3

51056

P28838

0.49

DHX36

170506

Q9H2U1

0.49

ESR1

2099

P03372

0.56

BAG1

573

Q99933

0.63

CD81

975

P60033

0.63

CDK2

1017

P24941

0.63

CHD3

1107

Q12873

0.63

CRMP1

1400

Q14194

0.63

ELAVL1

1994

Q15717

0.63

FN1

2335

P02751

0.63

ITGA4

3676

P13612

0.63

MCM2

4171

P49736

0.63

MYOC

4653

Q99972

0.63

NTRK1

4914

P04629

0.63

RPA1

6117

P27694

0.63

SH3GL1

6455

Q99961

0.63

TLE1

7088

Q04724

0.63

SUMO1

7341

P63165

0.63

VIM

7431

P08670

0.63

CUL3

8452

Q13618

0.63

EED

8726

O75530

0.63

CUL7

9820

Q14999

0.63

ARPC4

10093

P59998

0.63

ACTR3

10096

P61158

0.63

ACTR2

10097

P61160

0.63

ARPC2

10109

O15144

0.63

SRRM1

10250

Q8IYB3

0.63

COPS5

10987

Q92905

0.63

SNW1

22938

Q13573

0.63

OBSL1

23363

O75147

0.63

NSUN2

54888

Q08J23

0.63

OTUB1

55611

Q96FW1

0.63

RPRD1B

58490

Q9NQG5

0.63

NIF3L1

60491

Q9GZT8

0.63

AARSD1

80755

Q9BTE6

0.63

MAEL

84944

Q96JY0

0.63

PUF60

22827

Q9UHX1

0.65

ATF2

1386

P15336

0.72

RAB32

10981

Q13637

0.72

CEP170P1

645455

Q96L14

0.72

MDM2

4193

Q00987

0.73

SNCG

6623

O76070

0.76

MAPK14

1432

Q16539

0.79

VCAM1

7412

P19320

0.82