BP

GO:0002026

regulation of the force of heart contraction

Any process that modulates the extent of heart contraction, changing the force with which blood is propelled.

IEA

BP

GO:0006955

immune response

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

TAS

BP

GO:0007165

signal transduction

The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.

IEA

BP

GO:0007595

lactation

The secretion of milk by the mammary gland.

TAS

BP

GO:0008284

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

IEA

BP

GO:0031652

positive regulation of heat generation

Any process that activates or increases the rate or extent of heat generation.

IEA

BP

GO:0042327

positive regulation of phosphorylation

Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule.

IEA

BP

GO:0042756

drinking behavior

The specific behavior of an organism relating to the intake of liquids, especially water.

IEA

BP

GO:0043576

regulation of respiratory gaseous exchange

Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment.

IEA

BP

GO:0045776

negative regulation of blood pressure

Any process in which the force of blood traveling through the circulatory system is decreased.

IEA

BP

GO:0045906

negative regulation of vasoconstriction

Any process that stops, prevents, or reduces the frequency, rate or extent of vasoconstriction.

IEA

BP

GO:0045909

positive regulation of vasodilation

Any process that activates or increases the frequency, rate or extent of vasodilation.

IEA

BP

GO:0051461

positive regulation of corticotropin secretion

Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin hormone from a cell.

IEA

BP

GO:0051466

positive regulation of corticotropin-releasing hormone secretion

Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell.

IEA

CC

GO:0005576

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

TAS

CC

GO:0005615

extracellular space

That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

IBA

CC

GO:0048471

perinuclear region of cytoplasm

Cytoplasm situated near, or occurring around, the nucleus.

IEA

MF

GO:0001664

G-protein coupled receptor binding

Interacting selectively and non-covalently with a G-protein coupled receptor.

IBA

MF

GO:0005102

receptor binding

Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.

TAS

MF

GO:0005179

hormone activity

The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process.

IEA

MF

GO:0031704

apelin receptor binding

Interacting selectively and non-covalently with an apelin receptor.

IEA