Gene Symbol | PEX11B |
Entrez ID | 8799 |
Uniprot ID | O96011 |
Description | peroxisomal biogenesis factor 11 beta |
Chromosomal Location | chr1: 145,911,350-145,918,837 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0007031 |
peroxisome organization |
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules. |
IDA|ISS |
BP |
GO:0007165 |
signal transduction |
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. |
ISS |
BP |
GO:0016559 |
peroxisome fission |
The division of a mature peroxisome within a cell to form two or more separate peroxisome compartments. |
IDA |
BP |
GO:0044375 |
regulation of peroxisome size |
Any process that modulates the volume of a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules. |
IDA |
BP |
GO:0051260 |
protein homooligomerization |
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer. |
IDA |
CC |
GO:0005777 |
peroxisome |
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism. |
IDA |
CC |
GO:0005778 |
peroxisomal membrane |
The lipid bilayer surrounding a peroxisome. |
IDA |
CC |
GO:0005779 |
integral component of peroxisomal membrane |
The component of the peroxisomal membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IDA|ISS |
CC |
GO:0016020 |
membrane |
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
IDA |
CC |
GO:0043234 |
protein complex |
A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical. |
IDA |
CC |
GO:0070062 |
extracellular exosome |
A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. |
IDA |
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
MF |
GO:0042803 |
protein homodimerization activity |
Interacting selectively and non-covalently with an identical protein to form a homodimer. |
IDA |
Domain ID | Description |
---|---|
IPR008733 |
Peroxisomal biogenesis factor 11 |
IPR011990 |
Tetratricopeptide-like helical domain |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa04146 |
Peroxisome |
KEGG |
UMLS CUI | UMLS Term |
---|---|
C0043459 |
Zellweger Syndrome |
C0282525 |
Adrenoleukodystrophy, Neonatal |
C0282527 |
Infantile Refsum Disease (Disorder) |
Tissue | Cell Type |
---|---|
endometrium |
glandular cells |
liver |
hepatocytes |
lung |
pneumocytes |
tonsil |
squamous epithelial cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
PEX11B |
8799 |
O96011 |
0.63 |
FIS1 |
51024 |
Q9Y3D6 |
0.63 |
PEX19 |
5824 |
P40855 |
0.90 |
HTT |
3064 |
P42858 |
0.63 |
PEX11A |
8800 |
O75192 |
0.63 |
FAF2 |
23197 |
Q96CS3 |
0.63 |
HECW2 |
57520 |
Q9P2P5 |
0.63 |
PEX11G |
92960 |
Q96HA9 |
0.63 |